Abstract: The present disclosure relates to the field of biomedicine, and in particular, to an improved mutant of a respiratory syncytial virus (RSV) fusion (F) protein and uses thereof. The mutant can form a trimeric structure without introducing a heterologous trimerization domain. Meanwhile, through mutation designs such as releasing internal electrostatic repulsion, deleting the furin cleavage site, truncating the C-terminal domain, and introducing interchain disulfide bonds, the protein is stabilized in the pre-fusion conformation and exhibits enhanced stability. The mutant in the present disclosure is highly immunogenic when used as a vaccine or a vaccine component and can induce the production of a high level of neutralizing antibodies in the immunized animal, which can be used in the preparation of a vaccine for the prevention or treatment of RSV infection, and can also be used as a reagent for the detection of RSV.

Abstract: A terminal correction circuit includes a first terminal replica model, a terminal voltage offset correction circuit, a second terminal replica model and a terminal resistance offset correction circuit. The first terminal replica model sets a resistance ratio of first and second adjustable resistors according to a voltage correction code, thereby adjusting a terminal voltage. The terminal voltage offset correction circuit compares the terminal voltage and a third power supply voltage and provides the voltage correction code according to the comparison result. The second terminal replica model sets a resistance ratio of third and fourth adjustable resistors according to the voltage correction code and reduces an equivalent resistance value between a half-voltage terminal and a ground voltage according to a resistance correction code.

Abstract: A tool head posture adjustment method and apparatus, and a readable storage medium are disclosed. Distances to laser points are measured by laser distance sensors, and the laser points can construct at least one plane, thereby determining each plane corresponding to a site to be checked; and a comprehensive normal vector of each plane is calculated, and posture parameters of a tool head of a robot are calculated by using a posture expression, thereby adjusting the tool head posture.

Abstract: An integrated polymer-derived ceramic (PDC) thin-film sensor produced by laser pyrolysis and additive manufacturing and a fabrication method thereof are provided. Using a metal component or an insulating material as a substrate, a PDC-doped composite insulating film layer with high density, high insulation, and high temperature resistance is formed by a layer-by-layer laser pyrolysis and additive manufacturing on the surface of the metal component, and a strain sensitive layer with excellent electrical conductivity is obtained by Weissenberg direct writing process PDC-doped filler sensitive grid on the composite insulating film layer and laser pyrolysis enhancing graphitization of PDC.

Abstract: A pixel circuit, a display substrate, a display panel, and a display device are provided. The pixel circuit includes: a first driving circuit, a second driving circuit, a first light-emitting control circuit, and a second light-emitting control circuit. The first light-emitting control circuit is configured to control a connection between the first driving circuit and the light-emitting element and a connection between the first driving circuit and the first power line to be turned on or off; the second light-emitting control circuit is configured to control a connection between the second driving circuit and the light-emitting element and a connection between the second driving circuit and the second power line to be turned on or off; the first driving circuit and the second driving circuit are configured to control a driving current for driving the light-emitting element to emit light based on the same data voltage.

Abstract: A display substrate includes a main display area, a secondary display area and a transition area; the secondary display area includes an aperture region, a first peripheral region and a second peripheral region, at least part of the first peripheral region being located between the aperture region and the second peripheral region; the aperture region includes display sub-pixels; the first peripheral region includes display sub-pixels and first virtual sub-pixels; the second peripheral region includes display sub-pixels and second virtual sub-pixels; the density of the display sub-pixels of the aperture region, the density of the display sub-pixels of the first peripheral region and the density of the display sub-pixels of the second peripheral region are the same; at least part of the transition area is located between the main display area and the second peripheral region; the main display area and the transition area both includes display sub-pixels.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes: a base substrate, a display region including a first region, a second region and a transition region; first light-emitting elements at the first region; second light-emitting elements, first pixel circuitries and second pixel circuitries at the transition region, each first pixel circuitry being arranged between adjacent second pixel circuitries, an orthogonal projection of at least one second pixel circuitry onto the base substrate at least partially overlapping an orthogonal projection of at least one second light-emitting element onto the base substrate; first conductive lines each coupled between at least one first pixel circuitry and at least one first light-emitting element; and second conductive lines each coupled to at least one first pixel circuitry and extending along the at least one first pixel circuitry to a side away from the at least one first light-emitting element.

Abstract: The present disclosure relates to the field of biomedicine, and in particular, to an improved mutant of a respiratory syncytial virus (RSV) fusion (F) protein and uses thereof. The mutant can form a trimeric structure without introducing a heterologous trimerization domain. Meanwhile, through mutation designs such as releasing internal electrostatic repulsion, deleting the furin cleavage site, truncating the C-terminal domain, and introducing interchain disulfide bonds, the protein is stabilized in the pre-fusion conformation and exhibits enhanced stability. The mutant in the present disclosure is highly immunogenic when used as a vaccine or a vaccine component and can induce the production of a high level of neutralizing antibodies in the immunized animal, which can be used in the preparation of a vaccine for the prevention or treatment of RSV infection, and can also be used as a reagent for the detection of RSV.

Abstract: According to one embodiment, a data processing apparatus includes an extraction unit that extracts a candidate for a resource used to provide a service and a candidate for a parameter used to control the resource, from a file in which a content of provision of the service is described, and a designation unit that receives a designation of a resource and a parameter to be used to provide the service among resources and parameters extracted by the extraction unit.

Abstract: A method of collecting anhydrous sodium sulfate from fly ash includes heating a purified sodium sulfate solution to 60° C. to 80° C., and adding a precipitation promoter to the purified sodium sulfate solution to precipitate anhydrous sodium sulfate crystal. The method further includes cooling the purified sodium sulfate solution and the anhydrous sodium sulfate crystal to 35° C. to 55° C. for precipitating more anhydrous sodium sulfate crystal, and collecting and drying the anhydrous sodium sulfate crystal.

Abstract: A resource determination device according to one embodiment includes: a model storage device that stores a model indicating a relationship among a processing load arranged in a virtual machine, resource arrangement of the virtual machine, and a predicted value of quality when the processing load is arranged in the virtual machine; a determination unit that determines whether or not a predicted value of the quality when it is assumed that a new processing load is arranged in the virtual machine in the model satisfies an appropriate quality requirement; and a control unit that controls change of resource arrangement of the virtual machine such that the predicted value satisfies the appropriate quality requirement when the determination unit determines that the predicted value does not satisfy the appropriate quality requirement.

Abstract: A display panel and a display device are provided.

Abstract: Provided are a display substrate and a display apparatus. The display substrate includes a first display region and a second display region, and a pixel density of the first display region is higher than a pixel density of the second display region. A first pixel circuit of a first sub-pixel in the first display region includes one pixel circuit unit, and a second pixel circuit of a second sub-pixel in the second display region includes two pixel circuit units. The first pixel circuit is configured to be connected with a first power voltage terminal to receive a first power voltage as a pixel power voltage, and the second pixel circuit is configured to be connected with a second power voltage terminal to receive a second power voltage as a pixel power voltage and the first power voltage is different from the second power voltage.

Abstract: A data processing apparatus according to one embodiment includes: an input unit that receives an input related to a situation when a user who uses a service uses the service; a storage device that stores information indicating a relationship between a situation when the service is used and a requirement related to provision of the service to the user; and a calculation unit that calculates a requirement related to provision of the service to the user on the basis of a result of input by the input unit and the information stored in the storage device.

Abstract: A display substrate, a preparation method therefor, and a display apparatus.

Abstract: A vehicle seating assembly is provided and includes an armrest configured to rotate about an axis and between an up position and a down position. An inertia latch has a ratchet and is configured to move between a disengaged position and an engaged position to inhibit unintended movement of the armrest in the event of a collision. Certain implementations include one or more gears.

Abstract: A multi-directional radiation leaky coaxial cable, including an inner conductor, an insulating layer, an outer conductor and a sheath which are sequentially and coaxially nested from inside to outside. The outer conductor is provided with at least two rows of slotted hole groups, the at least two rows of slotted hole groups are distributed at different angles in a circumferential direction of the outer conductor, and each row of slotted hole group includes a plurality of slotted hole arrays which are periodically arranged along an axial direction of the outer conductor. Each slotted hole array includes a plurality of slotted holes, pitches of the slotted hole groups are the same, and a periodic arrangement difference of two adjacent rows of slotted hole groups in the circumferential direction is half a pitch, such that a phase difference of respective excitation electric fields is 180°.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes: a base substrate, a display region including a first region, a second region and a transition region; first light-emitting elements at the first region; second light-emitting elements, first pixel circuitries and second pixel circuitries at the transition region, each first pixel circuitry being arranged between adjacent second pixel circuitries, an orthogonal projection of at least one second pixel circuitry onto the base substrate at least partially overlapping an orthogonal projection of at least one second light-emitting element onto the base substrate; first conductive lines each coupled between at least one first pixel circuitry and at least one first light-emitting element; and second conductive lines each coupled to at least one first pixel circuitry and extending along the at least one first pixel circuitry to a side away from the at least one first light-emitting element.

Abstract: A client application in a rich execution environment sends a registration instruction of a secure memory to a trusted application in a trusted execution environment, where the registration instruction carries a memory address. Based on the registration instruction, a trusted application calls a registration interface of an operating system in a trusted execution environment, and sends a registration request of the secure memory to a processor trusted framework unit, so that the processor trusted framework unit updates, based on the registration request, an attribute of memory space corresponding to the memory address to a secure attribute.