Abstract: An anti-FGFR2 antibody, an encoding nucleic acid of the antibody, a vector and host cell for the expression and production thereof, an antibody-drug conjugate, and a pharmaceutical composition comprising the antibody. The present invention further relates to the use of the antibody molecule in a drug for diagnosing a cancer caused by FGFR2-pathway-related dysregulation, and the use of the antibody or antibody-drug conjugate in the preparation of a medicament for treating a cancer caused by FGFR2-pathway-related dysregulation, in particular gastric cancer.

Abstract: The present invention discloses a three-dimensional in-situ characterization method for heterogeneity in generating and reserving performances of shale. The method includes the following steps: establishing a logging in-situ interpretation model of generating and reserving parameters based on lithofacies-lithofacies-well coupling, and completing single-well interpretation; establishing a 3D seismic in-situ interpretation model of generating and reserving parameters by using well-seismic coupling; establishing a spatial in-situ framework of a layer group based on lithofacies-well-seismic coupling, and establishing a spatial distribution trend framework of small layers of a shale formation by using 3D visualized comparison of a vertical well; and implementing 3D in-situ accurate characterization of shale generating and reserving performance parameters by using lithofacies-well-seismic coupling based on the establishment of the seismic-lithofacies dual-control parameter field.

Abstract: The present invention discloses a three-dimensional in-situ characterization method for heterogeneity in generating and reserving performances of shale. The method includes the following steps: establishing a logging in-situ interpretation model of generating and reserving parameters based on lithofacies-lithofacies-well coupling, and completing single-well interpretation; establishing a 3D seismic in-situ interpretation model of generating and reserving parameters by using well-seismic coupling; establishing a spatial in-situ framework of a layer group based on lithofacies-well-seismic coupling, and establishing a spatial distribution trend framework of small layers of a shale formation by using 3D visualized comparison of a vertical well; and implementing 3D in-situ accurate characterization of shale generating and reserving performance parameters by using lithofacies-well-seismic coupling based on the establishment of the seismic-lithofacies dual-control parameter field.

Abstract: A multi-functional multi-field coupling seepage experiment device includes a device body, a stress field control system, a temperature field control system, a fluid loading control system and a fluid seepage measurement system. The present invention further discloses seepage experiments performed on tight gas, shale gas, tight oil, shale oil, natural gas hydrate and geothermal heat in a multi-field coupling state of a temperature field, a stress field, a pore pressure field and a seepage field.

Abstract: A shale gas enrichment and accumulation classification method includes the following steps: S1, analyzing a shale gas enrichment and accumulation system to form shale gas enrichment and accumulation modes of different degrees; S2, dividing the shale gas enrichment and accumulation modes into a tectonic main control hydrocarbon generation source rock type shale gas enrichment and accumulation mode, a tectonic main control gas accumulation reservoir-type shale gas enrichment and accumulation mode and a tectonic main control protective stratum type enrichment and accumulation mode according to the differences of the degrees of structure evolution over shale gas hydrocarbon generation source rock, a gas accumulation reservoir and a protective stratum; and S3, dividing the tectonic main control hydrocarbon generation source rock type shale gas enrichment and accumulation mode into an autochthonous continuous biogenic shale gas enrichment and accumulation mode and an autochthonous thermogenic shale gas enrichment a

Abstract: A multi-functional multi-field coupling seepage experiment device includes a device body, a stress field control system, a temperature field control system, a fluid loading control system and a fluid seepage measurement system. The present invention further discloses seepage experiments performed on tight gas, shale gas, tight oil, shale oil, natural gas hydrate and geothermal heat in a multi-field coupling state of a temperature field, a stress field, a pore pressure field and a seepage field.