Patents by Inventor Chaodi DAI

Chaodi DAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20260116882
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 26, 2025
    Publication date: April 30, 2026
    Inventors: Chaodi Dai, Hongyan Guo, Darryl Kato, Scott E. Lazerwith, Jonathan William Medley, Thomas C.J. Mies, Hyung-Jung Pyun, William J. Watkins, Jennifer R. Zhang
  • KRAS G12D modulating compounds
    Patent number: 12448400
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Grant
    Filed: December 23, 2024
    Date of Patent: October 21, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Chaodi Dai, Juan A. Guerrero, Darryl Kato, Scott E. Lazerwith, Jonathan William Medley, Thomas C. J. Mies, Hyung-Jung Pyun, Hayato Shiotsu, Maoqun Tian, William J. Watkins, Jennifer R. Zhang
  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20250136621
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: December 23, 2024
    Publication date: May 1, 2025
    Inventors: Chaodi Dai, Juan A. Guerrero, Darryl Kato, Scott E. Lazerwith, Jonathan William Medley, Thomas C.J. Mies, Hyung-Jung Pyun, Hayato Shiotsu, Maoqun Tian, William J. Watkins, Jennifer R. Zhang
  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20250109147
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 6, 2024
    Publication date: April 3, 2025
    Inventors: Chaodi Dai, Juan A. Guerrero, Darryl Kato, Scott E. Lazerwith, Jonathan William Medley, Thomas C.J. Mies, Hyung-Jung Pyun, Hayato Shiotsu, Maoqun Tian, William J. Watkins, Jennifer R. Zhang
  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20250101042
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 5, 2024
    Publication date: March 27, 2025
    Inventors: Wilian Augusto Cortopassi Coelho, Chaodi Dai, Juan A. Guerrero, Hongyan Guo, Darryl Kato, Scott E. Lazerwith, Jonathan William Medley, Hyung-Jung Pyun, Maoqun Tian, William J. Watkins, Jennifer R. Zhang
  • KRAS MODULATING COMPOUNDS
    Publication number: 20250042922
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: June 27, 2024
    Publication date: February 6, 2025
    Inventors: Chaodi Dai, Julie Farand, Juan A. Guerrero, Tezcan Guney, Hongyan Guo, Jason R. Hudlicky, Darryl Kato, Irene N. Kiburu, Scott E. Lazerwith, Paulo A. Machicao Tello, James B.C. Mack, Erik P. McAuley, Jessica L. McKinley, Jonathan William Medley, Hyung-Jung Pyun, Thomas P. Stratton, Maoqun Tian, Jeremy R. Tuck, William J. Watkins, Jie Xu, Jennifer R. Zhang
  • KRAS Modulating Compounds
    Publication number: 20240383922
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: April 10, 2024
    Publication date: November 21, 2024
    Inventors: Wilian Augusto Cortopassi Coelho, Chaodi Dai, Katherine De La Fuente, Julie Farand, Juan A. Guerrero, Tezcan Guney, Hongyan Guo, Safaa S. Jamshed, Darryl Kato, Irene N. Kiburu, Scott E. Lazerwith, James B.C. Mack, Joshua L. Martin, Jessica L. McKinley, Jonathan William Medley, Hyung-Jung Pyun, Thomas P. Stratton, Rhiannon Thomas-Tran, Maoqun Tian, Vickie H. Tsui, William J. Watkins, Jie Xu, Adam D. Zajdlik, Jennifer R. Zhang
  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20230374036
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: April 20, 2023
    Publication date: November 23, 2023
    Inventors: Chaodi Dai, Juan A. Guerrero, Tezcan Guney, Hongyan Guo, Darryl Kato, Irene N. Kiburu, Scott E. Lazerwith, Jessica L. McKinley, Jonathan William Medley, Hyung-Jung Pyun, Maoqun Tian, Vickie H. Tsui, William J. Watkins, Adam D. Zajdlik, Jennifer R. Zhang
  • KRAS G12D MODULATING COMPOUNDS
    Publication number: 20230339981
    Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 26, 2023
    Inventors: Chaodi DAI, Juan A. GUERRERO, Tezcan GUNEY, Hongyan GUO, Darryl KATO, Irene N. KIBURU, Scott E. LAZERWITH, Jessica L. MCKINLEY, Jonathan William MEDLEY, Hyung-Jung PYUN, Maoqun TIAN, Vickie H. TSUI, William J. WATKINS, Adam D. ZAJDLIK, Jennifer R. ZHANG