Patents by Inventor Chaohui DAI

Chaohui DAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NKG2A ANTIBODY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20220259306
    Abstract: Provided are an antibody targeting NKG2A, a preparation method therefor and use thereof. Specifically, provided is a new mouse or humanized monoclonal antibody targeting NKG2A, and a method for preparing the monoclonal antibody. The monoclonal antibody can bind to an NKG2A antigen with high specificity, and has high affinity and significant activities such as anti-tumor activity.
    Type: Application
    Filed: November 6, 2019
    Publication date: August 18, 2022
    Inventors: Qing DUAN, Lile LIU, Dazhi YANG, Jing GAO, Lili HU, Ruirui SUI, Dongxu WANG, Ye HAN, Rongrong XIE, Yan LU, Xiaohui SHAO, Jie ZHANG, Wenming ZHOU, Cuicui GUO, Guozhen TONG, Lina WANG, Chaohui DAI, Mengying WANG
  • FULLY HUMANIZED ANTI-GITR ANTIBODY AND PREPARATION METHOD THEREFOR
    Publication number: 20220119541
    Abstract: Disclosed are a GITR-targeting antibody, a preparation method therefor and the use thereof. In particular, disclosed is a novel GITR-targeting chimeric antibody or a fully humanized monoclonal antibody. Also disclosed is a method for preparing the monoclonal antibody. The monoclonal antibody of the present invention can bind to a GITR antigen with a high specificity, and has a very high affinity and a significant anti-tumor activity or the like.
    Type: Application
    Filed: November 29, 2019
    Publication date: April 21, 2022
    Applicant: PHARMAEXPLORER LIMITED
    Inventors: Qianqian QI, Qing DUAN, Lile LIU, Tatchi Teddy YANG, Hu LIU, Hui MA, Xinxiu YANG, Dongxu WANG, Chaohui DAI, Mengying WANG
  • ANTI-HUMAN TIM-3 MONOCLONAL ANTIBODY AND APPLICATION THEREOF
    Publication number: 20220033501
    Abstract: Provided are a high-affinity full human monoclonal antibody highly specifically targeting to TIM-3 and a preparation method therefor. The monoclonal antibody has a remarkable antitumor activity, and can be used for preparing a related diagnostic reagent or a pharmaceutical composition preventing or treating diseases related to TIM-3 dysfunction.
    Type: Application
    Filed: December 2, 2019
    Publication date: February 3, 2022
    Inventors: Ningning SONG, Qing DUAN, Lile LIU, Tatchi Teddy YANG, Lina XU, Hu LIU, Peipei WEI, Qian WANG, Yuangdong WANG, Xiaohui SHAO, Shaoping HU, Yu ZHANG, Jian WU, Meilling WANG, Dongxu WANG, Chaohui DAI, Mengying WANG
  • CD47 ANTIBODY, PREPARATION METHOD THEREFOR AND USES THEREOF
    Publication number: 20220017615
    Abstract: An antibody targeting CD47, a preparation method therefor and uses thereof. A novel mouse or human-mouse chimeric antibody targeting CD47. A method for preparing the monoclonal antibody. The monoclonal antibody of the present invention can bind CD47 antigen with high specificity, has high affinity and significant activities, such as anti-tumor activity.
    Type: Application
    Filed: December 3, 2019
    Publication date: January 20, 2022
    Inventors: Lile LIU, Tatchi Teddy YANG, Shireen KHAN, Qing DUAN, Jing GAO, Jingyun YAO, Zhiqiang XU, Yali MENG, Liang WANG, Mingming PAN, Wenming ZHOU, Ke XIA, Cuicui GUO, Guozhen TONG, Lu WANG, Jiaxun ZHAO, Dongxu WANG, Chaohui DAI, Mengying WANG
  • ANTI-HUMAN INTERLEUKIN 5(IL-5) MONOCLONAL ANTIBODY AND USE THEREOF
    Publication number: 20220010008
    Abstract: Disclosed in the present invention are an antibody targeting IL-5, a preparation method therefor and use thereof. In particular, disclosed in the present invention is a novel murine-derived or chimeric monoclonal antibody targeting IL-5. Also disclosed in the present invention is a method for preparing said monoclonal antibody. The monoclonal antibody of the present invention is capable of binding IL-5 antigen with high specificity, has high affinity and can well alleviate a series of asthma symptoms caused by IL-5, thereby achieving the effect of treating asthma.
    Type: Application
    Filed: December 11, 2019
    Publication date: January 13, 2022
    Inventors: Yizhen YANG, Songlin YANG, Jian WU, Xinxiu YANG, Xiaohui SHAO, Qin ZHONG, Shaoping HU, Qing DUAN, Lile LIU, Dongxu WANG, Chaohui DAI, Mengying WANG