Patents by Inventor Chaoji HUANGFU

Chaoji HUANGFU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for separating and purifying ?2-macroglobulin from Cohn Fraction IV precipitation
    Patent number: 11066441
    Abstract: The present invention discloses a method for separating and purifying ?2-macroglobulin from Cohn Fraction IV precipitation, in which Cohn Fraction IV precipitation is treated by ammonium sulfate precipitation, zinc ion affinity chromatography, gel filtration, and ultrafiltration and concentration sequentially and thereby ?2-macroglobulin is obtained finally. With the method provided in the present invention, purified ?2-macroglobulin plasma protein that has a clinical application value is obtained, the Cohn Fraction IV precipitation is changed from a discarded material into a valuable material, and plasma is utilized comprehensively. In addition, the method is easy and simple to use, easy to scale up, and suitable for separation and purification of ?2-macroglobulin at a large scale.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: July 20, 2021
    Assignee: ACADEMY OF MILITARY MEDICAL SCIENCES
    Inventors: Yuyuan Ma, Chaoji Huangfu, Xiong Zhao, Maomin LV, Jingang Zhang, Junting Jia
  • METHOD FOR SEPARATING AND PURIFYING ALPHA2-MACROGLOBULIN FROM COHN FRACTION IV PRECIPITATION
    Publication number: 20180282368
    Abstract: The present invention discloses a method for separating and purifying ?2-macroglobulin from Cohn Fraction IV precipitation, in which Cohn Fraction IV precipitation is treated by ammonium sulfate precipitation, zinc ion affinity chromatography, gel filtration, and ultrafiltration and concentration sequentially and thereby ?2-macroglobulin is obtained finally. With the method provided in the present invention, purified ?2-macroglobulin plasma protein that has a clinical application value is obtained, the Cohn Fraction IV precipitation is changed from a discarded material into a valuable material, and plasma is utilized comprehensively. In addition, the method is easy and simple to use, easy to scale up, and suitable for separation and purification of ?2-macroglobulin at a large scale.
    Type: Application
    Filed: September 14, 2016
    Publication date: October 4, 2018
    Applicant: ACADEMY OF MILITARY MEDICAL SCIENCES
    Inventors: Jingang ZHANG, Chaoji HUANGFU, Xiong ZHAO, Maomin LV, Yuyuan MA, Junting JIA