Abstract: The invention relates to crystalline forms of (6aR,10aR)-1-Hydroxy-6, 6-dimethyl-3-(2-methyl-2-octanyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene-9-carboxylic acid (ajulemic acid), including pharmaceutical compositions comprising a crystalline form of ajulemic acid and methods of making a crystalline form of ajulemic acid. The invention also relates to the use of pharmaceutical compositions comprising a crystalline form of ajulemic acid for the treatment of disease, including inflammatory diseases and fibrotic diseases.

Abstract: The present disclosure relates to salts and crystalline forms of a compound having the formula: Also described are processes for the production of the salts and crystalline forms described herein.

Abstract: The present disclosure relates to salts and crystalline forms of a compound having the formula (I): Also described are processes for the production of the salts and crystalline forms described herein.

Abstract: The invention provides compositions containing a stable crystalline form of brequinar and methods of making such composition. The invention also provides methods of using such compositions to treat a condition in a subject.

Abstract: The invention provides compositions containing a stable crystalline form of brequinar and methods of making such composition. The invention also provides methods of using such compositions to treat a condition in a subject.

Abstract: The invention provides immunochromatographic test strips and methods and systems or kits for detecting and quantifying S-Adenosylmethionine (SAM), S-Adenosylhomocysteine (SAH) and Homocysteine (HCy) in a sample, comprising: (a) making fluorophore conjugated antibodies; (b) immobilizing SAM, SAH and HCy on a solid support; (c) providing a sample, combining said sample with a conjugate selected from the group consisting of lanthanide chelate conjugates and quantum dot conjugates (QD) with anti-SAM, anti-SAH or anti-HCy, wherein said combining is performed under conditions that allow formation of a competitive complex comprising said conjugate, said SAM, SAH or HCy on the solid support and SAM, SAH or HCy in a sample when present; and (d) detecting the presence of the complex, if present, by monitoring a spectral emission mediated by the fluorescent conjugates in the complex, wherein the emission indicates the presence and quantity of SAM, SAH or HCy in the sample.

Abstract: The present disclosure relates to salts and crystalline forms of a compound having the formula (I): Also described are processes for the production of the salts and crystalline forms described herein.

Abstract: A hand-held vacuum cleaner (100) is provides, including a housing (1) and a floor brush (200), the housing (1) is provided with an air inlet (111) and an air blowing vent (121), the air blowing vent (121) is disposed adjacent to the air inlet (111); the floor brush (200) is provided with a floor brush inlet (201), a floor brush outlet (203) and a floor brush opening (202), the floor brush inlet (201) is in communication with the air blowing vent (121), the floor brush outlet (203) is in communication with the air inlet (111), the floor brush opening (202) is located at a side of the floor brush (200) away from the housing (1), and an airflow blowing from the air blowing vent (121) first flows to the floor brush opening (202) through the floor brush inlet (201), and then flows to the air inlet (111) through the floor brush outlet (203).

Abstract: A charging stand (100) for a vacuum cleaner (200) includes: a body (1), a charger (7) and a wire-winding frame (6). The charger (7) is connected with the body (1) via a power cord (71) and provided with a pin (72); the wire-winding frame (6) is disposed to the body (1) and defines an inserting slot (611), in which the pin (72) is configured to be fitted with the inserting slot (611), and the power cord (71) is configured to be wound around the wire-winding frame (6).

Abstract: A rechargeable vacuum cleaner assembly includes: a rechargeable vacuum cleaner provided with a first magnetic member (1011); and a charging stand (100) provided with a second magnetic member (1012), in which the first magnetic member (1011) is configured to cooperate with the second magnetic member (1012) through magnetic attraction so as to position the rechargeable vacuum cleaner to the charging stand (100).

Abstract: A charging stand (100) for a vacuum cleaner (200) includes a body (1), a pedal (2) and a safety protection device (3). The pedal (2) is disposed to the body (1) and is pivotable between a first position and a second position. The safety protection device (3) is disposed to the body (1), normally cooperate with the pedal (2), and separate from cooperation with the pedal (2) to make the pedal (2) move from the first position to the second position when moved.

Abstract: A crystalline form of 2,2-difluoro-N-[(1R,2S)-3-methyl-1-{[1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yl]oxy}-1-phenylbutan-2-yl]propanamide (form C), pharmaceutical compositions containing it and its use in therapy.

Abstract: A charging stand (100) for a vacuum cleaner (200) includes: a body (1); and a pedal (2) disposed on the body (1) and pivotable between a first position and a second position, wherein when the pedal (2) is in the first position, the vacuum cleaner (200) is suitable to be placed on the pedal (2) to be charged.

Abstract: The invention provides immunochromatographic test strips and methods and systems or kits for detecting and quantifying S-Adenosylmethionine (SAM), S-Adenosylhomocysteine (SAH) and Homocysteine (HCy) in a sample, comprising: (a) making fluorophore conjugated antibodies; (b) immobilizing SAM, SAH and HCy on a solid support; (c) providing a sample, combining said sample with a conjugate selected from the group consisting of lanthanide chelate conjugates and quantum dot conjugates (QD) with anti-SAM, anti-SAH or anti-HCy, wherein said combining is performed under conditions that allow formation of a competitive complex comprising said conjugate, said SAM, SAH or HCy on the solid support and SAM, SAH or HCy in a sample when present; and (d) detecting the presence of the complex, if present, by monitoring a spectral emission mediated by the fluorescent conjugates in the complex, wherein the emission indicates the presence and quantity of SAM, SAH or HCy in the sample.

Abstract: A charging stand (100) for a vacuum cleaner (200) includes: a body (1); and a blade (4) vertically disposed on the body (1), in which the blade (4) extends curvedly along a length direction of the blade (4) and is configured to cut off hairs wound around a brushroll (201) of the vacuum cleaner (200).

Abstract: A rechargeable vacuum cleaner assembly includes: a rechargeable vacuum cleaner provided with a first magnetic member (1011); and a charging stand (100) provided with a second magnetic member (1012), in which the first magnetic member (1011) is configured to cooperate with the second magnetic member (1012) through magnetic attraction so as to position the rechargeable vacuum cleaner to the charging stand (100).

Abstract: A charging stand (100) for a vacuum cleaner (200) includes: a body (1), a charger (7) and a wire-winding frame (6). The charger (7) is connected with the body (1) via a power cord (71) and provided with a pin (72); the wire-winding frame (6) is disposed to the body (1) and defines an inserting slot (611), in which the pin (72) is configured to be fitted with the inserting slot (611), and the power cord (71) is configured to be wound around the wire-winding frame (6).

Abstract: The invention provides immunochromatographic test strips and methods for detecting and quantifying S-Adenosylmethionine (SAM), S-Adenosylhomocysteine (SAH) and Homocysteine (HCy) in a sample, comprising: (a) making fluorophore conjugated antibodies; (b) immobilizing SAM, SAH and HCy on a solid support; (c) providing a sample, combining said sample with a conjugate selected from the group consisting of lanthanide chelate conjugates and quantum dot conjugates (QD) with anti-SAM, anti-SAH or anti-HCy, wherein said combining is performed under conditions that allow formation of a competitive complex comprising said conjugate, said SAM, SAH or HCy on the solid support and SAM, SAH or HCy in a sample when present; and (d) detecting the presence of the complex, if present, by monitoring a spectral emission mediated by the fluorescent conjugates in the complex, wherein the emission indicates the presence and quantity of SAM, SAH or HCy in the sample.

Abstract: A hand-held vacuum cleaner (100) is provides, including a housing (1) and a floor brush (200), the housing (1) is provided with an air inlet (111) and an air blowing vent (121), the air blowing vent (121) is disposed adjacent to the air inlet (111); the floor brush (200) is provided with a floor brush inlet (201), a floor brush outlet (203) and a floor brush opening (202), the floor brush inlet (201) is in communication with the air blowing vent (121), the floor brush outlet (203) is in communication with the air inlet (111), the floor brush opening (202) is located at a side of the floor brush (200) away from the housing (1), and an airflow blowing from the air blowing vent (121) first flows to the floor brush opening (202) through the floor brush inlet (201), and then flows to the air inlet (111) through the floor brush outlet (203).