Patents by Inventor Charbel Diab

Charbel Diab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymeric carrier
    Patent number: 9006193
    Abstract: Provided herein are polymeric carriers suitable for the delivery of polynucleotides (e.g. oligonucleotides) and/or other therapeutic agents into a living cell.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: April 14, 2015
    Assignees: University of Washington, PhaseRx, Inc.
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony J. Convertine, Craig L. Duvall, Danielle Benoit, Robert W. Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E. E. Paschal, Charbel Diab, Priyadarsi De
  • HYDROPHOBIC BLOCK CONJUGATED THERAPEUTIC AGENTS
    Publication number: 20130017167
    Abstract: Provided herein are polymers having a therapeutic agent covalently coupled to a hydrophobic block thereof, as well as micelles and therapeutic compositions thereof.
    Type: Application
    Filed: November 12, 2010
    Publication date: January 17, 2013
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Sean D. Monahan, Paul H. Johnson, Charbel Diab, Priyadarsi De, Patrick S. Stayton, Allan S. Hoffman
  • TARGETING MONOMERS AND POLYMERS HAVING TARGETING BLOCKS
    Publication number: 20130011362
    Abstract: Provided herein are monomers incorporating folate or other targeting agent, polymers prepared therefrom, polymers prepared therefrom having a therapeutic agent covalently coupled thereto, as well as micelles and therapeutic compositions thereof.
    Type: Application
    Filed: November 17, 2010
    Publication date: January 10, 2013
    Applicants: PhaseRx, Inc., University of Washington through its Center for Commercialization
    Inventors: Sean D. Monahan, Paul H. Johnson, Michael S. DeClue, Priyadarsi De, Anna S. Gall, Patrick S. Stayton, Allan S. Hoffman, Charbel Diab
  • HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY
    Publication number: 20120021514
    Abstract: Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent.
    Type: Application
    Filed: May 13, 2009
    Publication date: January 26, 2012
    Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTON
    Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
  • MULTIBLOCK COPOLYMERS
    Publication number: 20110286957
    Abstract: Provided herein are multiblock copolymers, as well as micelles and therapeutic compositions thereof.
    Type: Application
    Filed: November 6, 2009
    Publication date: November 24, 2011
    Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTON
    Inventors: Mary G. Prieve, Paul H. Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert W. Overell, Anna S. Gall, Amber E.E. Paschal, Charbel Diab, Priyadarsi De, Michael S. DeClue, Sean D. Monahan
  • MICELLES OF HYDROPHILICALLY SHIELDED MEMBRANE-DESTABILIZING COPOLYMERS
    Publication number: 20110281934
    Abstract: Provided herein are micelles comprising a plurality of copolymers. In certain instances, micelles provided herein are pH sensitive particles.
    Type: Application
    Filed: May 13, 2009
    Publication date: November 17, 2011
    Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTON
    Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
  • POLYMERIC CARRIER
    Publication number: 20110143435
    Abstract: Provided herein are polymeric carriers suitable for the delivery of polynucleotides (e.g. oligonucleotides) and/or other therapeutic agents into a living cell.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 16, 2011
    Applicants: UNIVERSITY OF WASHINGTON, PHASERX, INC.
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony J. Convertine, Craig L. Duvall, Danielle Benoit, Robert W. Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
  • MICELLES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS
    Publication number: 20110142951
    Abstract: Composition comprising a polymeric micelle and an associated polynucleotide.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 16, 2011
    Applicants: UNIVERSITY OF WASHINGTON, PHASERX, INC.
    Inventors: Paul H. Johnson, Patrick S. Stayton, Allan S. Hoffman, Anthony J. Convertine, Robert W. Overell, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
  • TARGETED POLYMER BIOCONJUGATES
    Publication number: 20110129921
    Abstract: Polymer bioconjugate having a RNAi agent covalently coupled to the alpha or omega end of a pH-dependent membrane-destabilizing polymer.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 2, 2011
    Applicants: UNIVERSITY OF WASHINGTON, PHASERX, INC.
    Inventors: Paul H. Johnson, Patrick S. Stayton, Allan S. Hoffman, Anthony J. Convertine, Craig L. Duvall, Danielle Benoit, Chen-Chang Lee, Robert W. Overell, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De
  • MICELLIC ASSEMBLIES
    Publication number: 20110123636
    Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instances, micellic assemblies provided herein are pH sensitive particles.
    Type: Application
    Filed: May 13, 2009
    Publication date: May 26, 2011
    Applicants: UNIVERSITY OF WASHINGTON, PHASERX, INC.
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert W. Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E.E. Paschal, Charbel Diab, Priyadarsi De