Patents by Inventor Charina Yap

Charina Yap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, compositions, and automated systems for separating rare cells from fluid samples
    Patent number: 7166443
    Abstract: The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnormalities or a variety of genetic conditions. In addition, the present invention recognizes that the enrichment of rare malignant cells from patient samples, can aid in diagnosis, prognosis, and development of therapeutic modalities for patients. The invention includes microfabricated filters for filtering fluid samples and methods of enriching rare cells of fluid samples using microfabricated filters of the present invention. The invention also includes solutions for the selective sedimentation of red blood cells (RBCs) from a blood sample and methods of using selective RBC sedimentation solutions for enriching rare cells of a fluid sample.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: January 23, 2007
    Assignee: Aviva Biosciences Corporation
    Inventors: George Walker, Junquan Xu, Douglas Yamanishi, Paul Hujsak, Lei Wu, Mingxian Huang, Guoliang Tao, Sara Snyder, Charina Yap
  • Methods, compositions, and automated systems for separating rare cells from fluid samples
    Publication number: 20040142463
    Abstract: The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnormalities or a variety of genetic conditions. In addition, the present invention recognizes that the enrichment of rare malignant cells from patient samples, can aid in diagnosis, prognosis, and development of therapeutic modalities for patients. The invention includes microfabricated filters for filtering fluid samples and methods of enriching rare cells of fluid samples using microfabricated filters of the present invention. The invention also includes solutions for the selective sedimentation of red blood cells (RBCs) from a blood sample and methods of using selective RBC sedimentation solutions for enriching rare cells of a fluid sample.
    Type: Application
    Filed: November 4, 2003
    Publication date: July 22, 2004
    Inventors: George Walker, Junquan Xu, Douglas Yamanishi, Paul Hujsak, Lei Wu, Mingxian Huang, Guoliang Tao, Sara Snyder, Charina Yap