Patents by Inventor Charlems Alvarez Jimenez

Charlems Alvarez Jimenez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11798179
    Abstract: The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment.
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: October 24, 2023
    Assignee: Case Western Reserve University
    Inventors: Anant Madabhushi, Jacob Antunes, Zhouping Wei, Pallavi Tiwari, Satish E. Viswanath, Charlems Alvarez Jimenez
  • Publication number: 20220012902
    Abstract: The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment.
    Type: Application
    Filed: September 22, 2021
    Publication date: January 13, 2022
    Inventors: Anant Madabhushi, Jacob Antunes, Zhouping Wei, Pallavi Tiwari, Satish E. Viswanath, Charlems Alvarez Jimenez