Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: This disclosure describes embodiments of systems, methods, and non-transitory computer-readable storage media that can solve one or more of the foregoing (or other problems) in the art in addition to providing other benefits by applying customized security limitations to a secure digital account, and removing the security limitations based on efficiently verifying personal identity information associated with the secure digital account. For example, the disclosed system can receive a user interaction associated with a secure digital account and determine a fraud risk score corresponding to the interaction. The system can then assign the secure digital account a security tier and apply appropriate security limitations based on the security tier that corresponds with a determined risk of fraud.

Abstract: Mechanisms are disclosed for securing a catheter in place to facilitate puncturing a hole through a vessel wall. The securing mechanisms include mechanically releasing arms that press against the wall of the vessel. The mechanically releasing arms are advanced out of the catheter. Outside of the catheter, the securing mechanisms angle or curve toward the vessel wall to contact the wall. The more the mechanically releasing arms are advanced, the closer the approach to the wall and the more force placed against the wall to anchor the catheter in place. The mechanically releasing arms include a plurality of wires that angle or curve toward the vessel wall when deployed, one or more wires that coil away from the catheter to contact the vessel wall when deployed, or a stopper arm with a curved endcap that contacts the vessel wall when deployed.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

Abstract: The present invention provides methods of maturing a peptide library and of identifying peptides having increased specific binding to a target molecule and/or differential specific binding to target molecules. The present invention also provide methods of developing diagnostic assays, detection kits and therapeutic agents with the peptides.

Abstract: The present disclosure provides isolated Paenibacillus strains useful for fixing atmospheric nitrogen and enhancing crop yield, as well as inoculant compositions comprising one or more of the isolated strains, seeds that have been treated with one or more of the isolated strains, and methods of using the isolated strains to improve nitrogen content, crop yield, etc.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

Abstract: An example method includes receiving, by a mobile computing device, electrical power via a wireless charging link between the mobile computing device and a wireless charging device; and responsive to an activation state of a camera of the mobile computing device, selectively adjusting, by the mobile computing device, one or more parameters of the wireless charging link, wherein wireless charging via the wireless charging link with the adjusted one or more parameters generates less noise in images captured by the camera while the mobile computing device receives electrical power via the wireless charging link than wireless charging with unadjusted one or more parameters.

Abstract: An example method includes receiving, by a mobile computing device, electrical power via a wireless charging link between the mobile computing device and a wireless charging device; and responsive to an activation state of a camera of the mobile computing device, selectively adjusting, by the mobile computing device, one or more parameters of the wireless charging link, wherein wireless charging via the wireless charging link with the adjusted one or more parameters generates less noise in images captured by the camera while the mobile computing device receives electrical power via the wireless charging link than wireless charging with unadjusted one or more parameters.

Abstract: Infused oil polishing systems and methods reduce or remove chlorophyll from bulk biomass saturated ethanol. A processing vessel includes a valved input port for receiving a biomass mixture and a valved output port for expelling a polished mixture containing the desired extract. The vessel is pressurized or evacuated, causing the chlorophyll-containing carbon to be trapped by the filter assembly as the desired extract mixture is discharged. The equipment operates at relatively low pressures of 40 psi or less, and one operator can run multiple units. The end user can control the degree of polishing by adjusting the amount of media used and resident time. The basic apparatus can also be modified to run in parallel or series combinations to increase throughput. An optional elevating rack provides for ease of cleaning, and no expensive ancillary equipment needs to be purchased.

Abstract: The present disclosure provides isolated Microbacterium trichothecenolyticum strains useful for enhancing crop yield, as well as incoluant compositions comprising one or more of the isolated strains, seeds that have been treated with one or more of the isolated strains, and methods of using the isolated strains to enhance root nodulation, nutrient uptake, chlorophyll content, etc.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.