Patents by Inventor Charles A. Harrington
Charles A. Harrington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11926966Abstract: A method of increasing chemical efficiency of chemical additives in a papermaking system includes the steps of providing thick stock pulp comprising soluble lignin, process water, and at least about 2% by weight of cellulosic fiber based on total weight of thick stock pulp, and adding at least one organic polymer to the thick stock pulp to reduce the amount of soluble lignin therein. The organic polymer is chosen from cationic polymers, non-ionic polymers and combinations thereof.Type: GrantFiled: October 30, 2020Date of Patent: March 12, 2024Assignee: SOLENIS TECHNOLOGIES, L.P.Inventors: Davit Edward Sharoyan, John Charles Harrington, IV, Valmir Frauches de Freitas, Flávio Henrique Gazzotti Bueno de Oliveira
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Publication number: 20210047780Abstract: A method of increasing chemical efficiency of chemical additives in a papermaking system includes the steps of providing thick stock pulp comprising soluble lignin, process water, and at least about 2% by weight of cellulosic fiber based on total weight of thick stock pulp, and adding at least one organic polymer to the thick stock pulp to reduce the amount of soluble lignin therein. The organic polymer is chosen from cationic polymers, non-ionic polymers and combinations thereof.Type: ApplicationFiled: October 30, 2020Publication date: February 18, 2021Applicant: SOLENIS TECHNOLOGIES, L.P.Inventors: Davit Edward Sharoyan, John Charles Harrington, IV, Valmir Frauches de Freitas, Flávio Henrique Gazzotti Bueno de Oliveira
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Patent number: 8475808Abstract: Recombinant production of immunogenic West Nile Virus (WNV) proteins is described. These proteins, heterodimers comprising the proteins, fusions thereof, polynucleotides encoding the proteins, and combinations thereof, as well as antibodies produced therefrom, can be used in immunogenic compositions for preventing, treating and diagnosing WNV infection. Also described are highly sensitive ELISA and strip immunoassay methods for detecting the presence of WNV in biological samples.Type: GrantFiled: May 21, 2004Date of Patent: July 2, 2013Assignee: Novartis Vaccines and Diagnostics, Inc.Inventors: William Andrews, David Chien, Qui-Lim Choo, Stephen Coates, Doris Coit, Charles Harrington, Susan Hilt, Michael Houghton, Angelica Medina-Selby, Sergio Pichuantes, Yiu-Lian Fong
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Patent number: 7795037Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.Type: GrantFiled: June 6, 2008Date of Patent: September 14, 2010Assignee: Novartis Vaccines and Diagnostics, Inc.Inventors: Willy Lagwinski, Charles Harrington, Bruce Phelps
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Publication number: 20080248587Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.Type: ApplicationFiled: June 6, 2008Publication date: October 9, 2008Inventors: Willy Lagwinski, Charles A. Harrington, Bruce H. Phelps
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Patent number: 7384795Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.Type: GrantFiled: September 5, 2003Date of Patent: June 10, 2008Assignee: Novartis Vaccines and Diagnostics, Inc.Inventors: Willy Lagwinski, Charles A. Harrington, Bruce H. Phelps
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Publication number: 20070191352Abstract: A composition and use thereof for the prophylaxis or treatment of Alzheimer's disease, motor neurone disease, Lewy body disease, Pick's disease or progressive supranuclear palsy. The composition includes an agent which modulates or inhibits tau-tau association and which does not inhibit tau-tubulin binding. In the method the agent is administered to an individual in order to achieve the desired therapeutic effect. Preferably the agent which is administered is a phenothiazine compound.Type: ApplicationFiled: December 11, 2006Publication date: August 16, 2007Applicant: The University Court of the University of AberdeenInventors: Claude Wischik, Patricia Edwards, Charles Harrington, Martin Roth, Aaron Klug
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Publication number: 20070092538Abstract: Recombinant production of immunogenic West Nile Virus (WNV) proteins is described. These proteins, heterodimers comprising the proteins, fusions thereof, polynucleotides encoding the proteins, and combinations thereof, as well as antibodies produced therefrom, can be used in immunogenic compositions for preventing, treating and diagnosing WNV infection. Also described are highly sensitive ELISA and strip immunoassay methods for detecting the presence of WNV in biological samples.Type: ApplicationFiled: May 21, 2004Publication date: April 26, 2007Inventors: William Andrews, David Chien, Qui-Lim Choo, Stephen Coates, Doris Coit, Charles Harrington, Susan Hilt, Michael Houghton, Angelica Medina-Selby, Sergio Pichuantes
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Publication number: 20070019704Abstract: A system and method for determining a temperature including: a temperature sensor including: a substrate resistance configured to be primarily responsive to a temperature of a substrate; and a membrane resistance configured to be primarily responsive to a temperature of a membrane. The substrate resistance and the membrane resistance are arranged in a series circuit configured to facilitate measurement of a voltage responsive to a temperature change. The system also includes a controller in operable communication with the temperature sensor. The method includes: receiving a temperature signal, the temperature signal indicative of a composite temperature variation including a first varying portion and a second varying portion; configuring the temperature signal to eliminate the second varying portion; and generating a temperature value based on the configuring wherein the temperature value is substantially based on the first varying portion.Type: ApplicationFiled: September 25, 2006Publication date: January 25, 2007Inventors: Michel Sultan, Charles Harrington, Da Wang
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Publication number: 20060287523Abstract: This invention pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain 3,7-diaminophenothiazin-5-ium compounds (referred to herein as “diaminophenothiazinium compounds”) including Methythioninium Chloride (MTC) (also known as Methylene Blue). In one embodiment, the method comprises the steps of, in order: nitrosylation (NOS); nitrosyl reduction (NR); thiosulfonic acid formation (TSAF); oxidative coupling (OC); Cr(VI) reduction (CR); isolation and purification of zwitterionic intermediate (IAPOZI); ring closure (RC); chloride salt formation (CSF); one of: sulphide treatment (ST); dimethyldithiocarbamate treatment (DT); carbonate treatment (CT); ethylenediaminetetraacetic acid treatment (EDTAT); organic extraction (OE); and recrystallisation (RX). The present invention also pertains to the resulting (high purity) compounds, compositions comprising them (e.g.Type: ApplicationFiled: March 29, 2006Publication date: December 21, 2006Inventors: Claude Wischik, Janet Rickard, Charles Harrington, David Horsley, John Storey, Colin Marshall, James Sinclair, Han Tan
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Publication number: 20060272151Abstract: An electrical contact comprises a conductive surface of nickel, tin, or a precious metal having a surface of formed grains and particles of a low friction polymer deposited on a portion of the grains wherein the resistance of the contact is about 1 ohm or less, measured at about 100 mA, and wherein the polymer particles are deposited on the grains from a dispersion of the particles in a liquid.Type: ApplicationFiled: August 15, 2006Publication date: December 7, 2006Inventors: Charles Harrington, George Drew, Neil Aukland
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Publication number: 20060246313Abstract: Described is a method of reducing corrosion of a silver-containing surface comprising electro-depositing a layer of an iodine-containing material on said silver surface at a charge density of about 80 mA*s (milliamps second)/cm2) or less. Also described is an electrical contact also produced by the method.Type: ApplicationFiled: April 28, 2005Publication date: November 2, 2006Inventors: Charles Harrington, Neil Aukland
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Publication number: 20060210824Abstract: Described is an electrical contact comprising a conductive surface of nickel, tin, or a precious metal having a surface of formed grains and particles of a low friction polymer deposited on a portion of the grains wherein the resistance of the contact is about 1 ohm or less, measured at about 100 mA, and wherein the polymer particles are deposited on the grains from a dispersion of the particles in a liquid.Type: ApplicationFiled: April 7, 2005Publication date: September 21, 2006Inventors: Charles Harrington, George Drew, Neil Aukland
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Publication number: 20060014216Abstract: A composition and use thereof for the prophylaxis or treatment of Alzheimer's disease, motor neurone disease, Lewy body disease, Pick's disease or progressive supranuclear palsy. The composition includes an agent which modulates or inhibits tau-tau association and which does not inhibit tau-tubulin binding. In the method the agent is administered to an individual in order to achieve the desired therapeutic effect. Preferably the agent which is administered is a phenothiazine compound.Type: ApplicationFiled: July 7, 2005Publication date: January 19, 2006Applicant: The University Court of the University of AberdeenInventors: Claude Wischik, Patricia Edwards, Charles Harrington, Martin Roth, Aaron Klug
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Publication number: 20050107472Abstract: Provided are napthoquinone-type compounds which can be used to modulate the aggregation of protein (e.g. tau) associated with neurodegenerative disease (e.g. Alzheimer's disease). Structure-function characteristics for oxidised and reduced napthoquinone-type compounds, such as menadione-related compounds, are disclosed. The invention further provides methods of treatment or prophylaxis of neurodegenerative diseases and/or clinical dementias based on the compounds.Type: ApplicationFiled: July 16, 2002Publication date: May 19, 2005Applicant: The University Court of the University of AberdeenInventors: Claude Wischik, David Horsley, Janet Rickard, Charles Harrington
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Publication number: 20050012588Abstract: A system and method for determining a temperature including: a temperature sensor including: a substrate resistance configured to be primarily responsive to a temperature of a substrate; and a membrane resistance configured to be primarily responsive to a temperature of a membrane. The substrate resistance and the membrane resistance are arranged in a series circuit configured to facilitate measurement of a voltage responsive to a temperature change. The system also includes a controller in operable communication with the temperature sensor. The method includes: receiving a temperature signal, the temperature signal indicative of a composite temperature variation including a first varying portion and a second varying portion; configuring the temperature signal to eliminate the second varying portion; and generating a temperature value based on the configuring wherein the temperature value is substantially based on the first varying portion.Type: ApplicationFiled: July 16, 2003Publication date: January 20, 2005Inventors: Michel Sultan, Charles Harrington, Da Wang
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Publication number: 20040197929Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.Type: ApplicationFiled: September 5, 2003Publication date: October 7, 2004Applicant: Chiron CorporationInventors: Willy Lagwinski, Charles A. Harrington, Bruce H. Phelps
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Patent number: 6673628Abstract: An analytical test device is described for the immunochromatographic determination of the presence of one or more analytes in fluid samples. The device is configured such that the sample is allowed to enter the detection zone simultaneously from many different directions, eliminating stagnation of the flow of the sample. By selection of the porous substrate, the device also allows for the separation of red blood cells from plasma, providing a rapid test for one or more analytes in a sample of whole blood. The device of the present invention may measure more than one analyte simultaneously from a single sample, either by having multiple immunochromatographic pathways fed by a single sample, or multiple analytes detected in the same pathway by way of multiple capture antibodies.Type: GrantFiled: February 6, 2001Date of Patent: January 6, 2004Assignee: Spectral Diagnostics, Inc.Inventors: Helmut E. Freitag, Qinwei Shi, Charles A. Harrington
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Patent number: 6410341Abstract: An analytical test device is described for the immunochromatographic determination of the presence of one or more analytes in fluid samples. The device is configured such that the sample is allowed to enter the detection zone simultaneously from many different directions, eliminating stagnation of the flow of the sample. By selection of the porous substrate, the device also allows for the separation of red blood cells from plasma, providing a rapid test for one or more analytes in a sample of whole blood. The device of the present invention may measure more than one analyte simultaneously from a single sample, either by having multiple immunochromatographic pathways fed by a single sample, or multiple analytes detected in the same pathway by way of multiple capture antibodies.Type: GrantFiled: July 14, 1999Date of Patent: June 25, 2002Assignee: Spectral Diagnostics, Inc.Inventors: Helmut E. Freitag, Qinwei Shi, Charles A. Harrington
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Patent number: 6324936Abstract: A cantilevered leaf spring is formed at its proximal end to the housing of a power equipment unit. The distal end of the spring carries a bushing which engages a control cable for operating components of the unit. The proximal end of the spring is adjustably secured to the housing to impart a desired spring force to the cable so as to remove slack therefrom and to properly tension the cable.Type: GrantFiled: April 18, 2000Date of Patent: December 4, 2001Assignee: Murray, Inc.Inventor: Charles Harrington