Patents by Inventor Charles A. McLaughlin

Charles A. McLaughlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11418573
    Abstract: This disclosure describes techniques for providing an abstraction layer for one or more file transfer tools that may operate on a public network, or on a network controlled by an organization or enterprise. In some examples, a computing system may serve as a front-end for a managed file transfer system that may hide some details of the operations performed by the file transfer system. The computing system may interact with one or more managed file transfer systems (or similar systems) to provision a data path between computing systems, perform a file transfer between the computing systems, perform sustainment tasks associated with the data path, and/or perform lifecycle management tasks associated with the data path.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: August 16, 2022
    Assignee: Wells Fargo Bank, N.A.
    Inventors: Thomas McLaughlin, Charles Eric Almond, James Ian Percival
  • Publication number: 20200291355
    Abstract: The present disclosure provides customizable enucleated erythroid cells or enucleated cells that can be engineered to include, on their surface, a loadable exogenous antigen-presenting polypeptide, wherein the loadable exogenous antigen-presenting polypeptide comprises one or more amino acid substitutions. In some embodiments, the one or more amino acid substitutions stabilize the loadable exogenous antigen-presenting polypeptide on the cell surface. In some embodiments, the loadable exogenous antigen-presenting polypeptide is stabilized on the cell surface in the absence of a polypeptide bound to the loadable exogenous antigen-presenting polypeptide. In some embodiments, the loadable exogenous antigen-presenting polypeptide comprises an exogenous displaceable polypeptide bound to the loadable exogenous antigen-presenting polypeptide. In some embodiments, the loadable exogenous antigen-presenting polypeptide is stabilized on the cell surface upon release of the displaceable polypeptide.
    Type: Application
    Filed: February 20, 2020
    Publication date: September 17, 2020
    Inventors: Tiffany Fen-Yi Chen, Thomas Joseph Wickham, Christopher Lawrence Moore, Shamael Rabia Dastagir, Douglas Charles Mclaughlin, Regina Sophia Salvat, Alex Richard Nanna
  • Publication number: 20140325034
    Abstract: A computer-implemented method for the creation of composite internet videos from streaming video feeds serving as an intermediary between an internet video user and a plurality of separate internet video sources. A user may invoke the service from a web page and fashion a composite video from a plurality of sources without copying or otherwise disturbing the source videos. The user's composite video is defined by an edit decision list (EDL) which specifies the location of the plurality of separate videos, the “cut in” and “cut out” locations within the separate videos where the composite video will transition between the separate videos, and an audio volume value associated with each video.
    Type: Application
    Filed: July 15, 2014
    Publication date: October 30, 2014
    Inventor: John Charles MCLAUGHLIN
  • Patent number: 8819185
    Abstract: A computer-implemented method for the creation of composite internet videos from streaming video feeds serving as an intermediary between an internet video user and a plurality of separate internet video sources. A user may invoke the service from a web page and fashion a composite video from a plurality of sources without copying or otherwise disturbing the source videos. The user's composite video is defined by an edit decision list (EDL) which specifies the location of the plurality of separate videos, the “cut in” and “cut out” locations within the separate videos where the composite video will transition between the separate videos, and an audio volume value associated with each video.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: August 26, 2014
    Inventor: John Charles McLaughlin
  • Publication number: 20130036201
    Abstract: A computer-implemented method for the creation of composite internet videos from streaming video feeds serving as an intermediary between an internet video user and a plurality of separate internet video sources. A user may invoke the service from a web page and fashion a composite video from a plurality of sources without copying or otherwise disturbing the source videos. The user's composite video is defined by an edit decision list (EDL) which specifies the location of the plurality of separate videos, the “cut in” and “cut out” locations within the separate videos where the composite video will transition between the separate videos, and an audio volume value associated with each video.
    Type: Application
    Filed: August 5, 2011
    Publication date: February 7, 2013
    Inventor: John Charles McLaughlin
  • Patent number: 7953830
    Abstract: Generally speaking, systems, methods and media for detection and network reconfiguration upon changes in dynamic host configuration protocol (DHCP) IP addresses are disclosed. Embodiments of a method may include setting a renew time and a rebind time of a DHCP configuration and establishing an IP address with a first DHCP server. Embodiments may also include, after passage of the renew time, transmitting a renew request to the first DHCP server at its IP address and, in response to failure to receive an acknowledgement message from the first DHCP server, determining if the first DHCP server IP address is still valid. Embodiments may also include, in response to determining that the first DHCP server IP address is not still valid, retrieving a second, different DHCP server IP address from a network change event signal and configuring a network adapter based on the second DHCP server IP address.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: May 31, 2011
    Assignee: International Business Machines Corporation
    Inventors: Robert K. Foster, Ajay K. Mahajan, Charles A. McLaughlin, Hemlata N. Reddy
  • Publication number: 20080109539
    Abstract: Generally speaking, systems, methods and media for detection and network reconfiguration upon changes in dynamic host configuration protocol (DHCP) IP addresses are disclosed. Embodiments of a method may include setting a renew time and a rebind time of a DHCP configuration and establishing an IP address with a first DHCP server. Embodiments may also include, after passage of the renew time, transmitting a renew request to the first DHCP server at its IP address and, in response to failure to receive an acknowledgement message from the first DHCP server, determining if the first DHCP server IP address is still valid. Embodiments may also include, in response to determining that the first DHCP server IP address is not still valid, retrieving a second, different DHCP server IP address from a network change event signal and configuring a network adapter based on the second DHCP server IP address.
    Type: Application
    Filed: November 7, 2006
    Publication date: May 8, 2008
    Inventors: Robert K. Foster, Ajay K. Mahajan, Charles A. McLaughlin, Hemlata N. Reddy
  • Publication number: 20060263406
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Application
    Filed: May 1, 2006
    Publication date: November 23, 2006
    Inventors: Mark Lyles, Charles McLaughlin, Glenn Halff, William Mallow
  • Publication number: 20060118514
    Abstract: A wire grid polarizer may be fabricated by forming plurality of substantially-straight metallic lines of predetermined periodicity ? on a thin film substrate A plurality of substantially straight nanometer-scale periodic surface relief structures is created on a surface of the substrate. The periodic surface relief structures cover a region greater than about 4 centimeters in length and greater than about 4 centimeters in width, wherein the periodicity ? is between about 10 nanometers and about 500 nanometers. One or more layers of material are formed on the periodic relief structures. The one or more layers include one or more conductor materials that form the plurality of substantially straight metallic lines over a region of the substrate greater than about 4 centimeters in length and greater than about 4 centimeters in width.
    Type: Application
    Filed: November 28, 2005
    Publication date: June 8, 2006
    Applicant: Agoura Technologies, Inc.
    Inventors: Michael Little, Charles McLaughlin
  • Patent number: 7037304
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: May 2, 2006
    Assignee: Materials Evolution and Development USA, Inc.
    Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
  • Patent number: 7001371
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: February 21, 2006
    Assignee: MED USA
    Inventors: Charles A. McLaughlin, Mark B. Lyles, Glenn A. Halff, William A. Mallow
  • Publication number: 20050027668
    Abstract: A method, system, and computer program product are disclosed for managing an application's persistent data across multiple different release versions of the application. A format for a memory area is defined wherein the persistent data will be stored according to a first release version of the application. The format is organized to permit the application running at different release versions to access the memory area. The memory area is accessed using the application that is running at a second release version. The memory area is divided into individually accessible sections. The format includes a template file for each section for each release version.
    Type: Application
    Filed: July 31, 2003
    Publication date: February 3, 2005
    Applicant: International Business Machines Corporation
    Inventors: Robert Foster, Casey McCreary, Charles McLaughlin, Christine Wang
  • Publication number: 20020120251
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 29, 2002
    Applicant: MATERIALS EVOLUTION AND DEVELOPMENT USA, INC.
    Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
  • Patent number: 6340360
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Grant
    Filed: October 13, 1998
    Date of Patent: January 22, 2002
    Assignee: MED USA
    Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
  • Patent number: 5964745
    Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: October 12, 1999
    Assignee: Med USA
    Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
  • Patent number: 4891766
    Abstract: The present invention provides a contextual editor for an expert system. The editor leads the operator through a series of screens which designate classes of information, logical nodes, and the interrelation of the nodes. The screens are so arranged that they prevent the operator from providing classes or nodes with logically insufficient information. At the end of each definition the screen automatically shows a logical tree which graphically illustrates the logical interconnection between the nodes.The editor provided by the present invention provides the knowledge base developer with a guided knowledge entry system that modifies its behavior based on the context of the knowledge structures being entered. This approach not only facilitates the creation of the rules base knowledge, but also frequently prevents the user from entering invalid values or logic structures. Also, the guided editing approach allows the developer to learn and use the system much more quickly, thus becoming productive much sooner.
    Type: Grant
    Filed: June 15, 1989
    Date of Patent: January 2, 1990
    Assignee: International Business Machines Corporation
    Inventors: Andrew G. Derr, Charles A. McLaughlin
  • Patent number: 4683196
    Abstract: The subject invention provides a means for the immunological detection of an entire class of microorganisms in clinical samples. The detection is accomplished by reaction of the clinical sample iwth a class-specific immunological reagent. This reagent is an antiserum either monoclonal or polyclonal in nature, and the detection is based upon reaction of the antiserum with an antigenic determinant which is shared among all members of the detectable class of microorganisms. The presence of the resulting immunological reaction product (e.g. the antigen-antibody complex) may be detected by well-known immunological detection-systems.
    Type: Grant
    Filed: March 16, 1984
    Date of Patent: July 28, 1987
    Assignee: Meru, Inc.
    Inventor: Charles A. McLaughlin
  • Patent number: 4070865
    Abstract: An improved method and composition for consolidating a porous and permeable subterranean particulated formation into a high strength water resistant mass is provided by a particular combination of vinyl monomers, catalyst system and optional features such as solvent, particulate filler, chelates and binders.
    Type: Grant
    Filed: March 10, 1976
    Date of Patent: January 31, 1978
    Assignee: Halliburton Company
    Inventor: Homer Charles McLaughlin