Patents by Inventor Charles A. McLaughlin
Charles A. McLaughlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7953830Abstract: Generally speaking, systems, methods and media for detection and network reconfiguration upon changes in dynamic host configuration protocol (DHCP) IP addresses are disclosed. Embodiments of a method may include setting a renew time and a rebind time of a DHCP configuration and establishing an IP address with a first DHCP server. Embodiments may also include, after passage of the renew time, transmitting a renew request to the first DHCP server at its IP address and, in response to failure to receive an acknowledgement message from the first DHCP server, determining if the first DHCP server IP address is still valid. Embodiments may also include, in response to determining that the first DHCP server IP address is not still valid, retrieving a second, different DHCP server IP address from a network change event signal and configuring a network adapter based on the second DHCP server IP address.Type: GrantFiled: November 7, 2006Date of Patent: May 31, 2011Assignee: International Business Machines CorporationInventors: Robert K. Foster, Ajay K. Mahajan, Charles A. McLaughlin, Hemlata N. Reddy
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Publication number: 20080109539Abstract: Generally speaking, systems, methods and media for detection and network reconfiguration upon changes in dynamic host configuration protocol (DHCP) IP addresses are disclosed. Embodiments of a method may include setting a renew time and a rebind time of a DHCP configuration and establishing an IP address with a first DHCP server. Embodiments may also include, after passage of the renew time, transmitting a renew request to the first DHCP server at its IP address and, in response to failure to receive an acknowledgement message from the first DHCP server, determining if the first DHCP server IP address is still valid. Embodiments may also include, in response to determining that the first DHCP server IP address is not still valid, retrieving a second, different DHCP server IP address from a network change event signal and configuring a network adapter based on the second DHCP server IP address.Type: ApplicationFiled: November 7, 2006Publication date: May 8, 2008Inventors: Robert K. Foster, Ajay K. Mahajan, Charles A. McLaughlin, Hemlata N. Reddy
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Patent number: 7037304Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.Type: GrantFiled: September 24, 2001Date of Patent: May 2, 2006Assignee: Materials Evolution and Development USA, Inc.Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
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Patent number: 7001371Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.Type: GrantFiled: October 3, 2000Date of Patent: February 21, 2006Assignee: MED USAInventors: Charles A. McLaughlin, Mark B. Lyles, Glenn A. Halff, William A. Mallow
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Publication number: 20020120251Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.Type: ApplicationFiled: September 24, 2001Publication date: August 29, 2002Applicant: MATERIALS EVOLUTION AND DEVELOPMENT USA, INC.Inventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
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Patent number: 6340360Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.Type: GrantFiled: October 13, 1998Date of Patent: January 22, 2002Assignee: MED USAInventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
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Patent number: 5964745Abstract: An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and angiogenesis from adjacent vascular tissue into the implant. Infection shield embodiments stimulate cell growth and angiogenesis from adjacent vascular tissue which effectively blocks passage of pathogenic microorganisms along percutaneously implanted objects. In embodiments for drug delivery, a reservoir of the same biomaterial may contain either (1) a cell culture system enclosed within a porous sealable interior chamber or (2) a biodegradable matrix in which one or more drugs are dispersed. After implantation of a reservoir of the first embodiment in an organism, cultured cells obtain food and oxygen via diffusion in tissue fluid through the porous walls of the interior chamber, while metabolic products, including drugs, diffuse away from the cell culture in an analogous manner.Type: GrantFiled: March 18, 1996Date of Patent: October 12, 1999Assignee: Med USAInventors: Mark B. Lyles, Charles A. McLaughlin, Glenn A. Halff, William A. Mallow
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Patent number: 4891766Abstract: The present invention provides a contextual editor for an expert system. The editor leads the operator through a series of screens which designate classes of information, logical nodes, and the interrelation of the nodes. The screens are so arranged that they prevent the operator from providing classes or nodes with logically insufficient information. At the end of each definition the screen automatically shows a logical tree which graphically illustrates the logical interconnection between the nodes.The editor provided by the present invention provides the knowledge base developer with a guided knowledge entry system that modifies its behavior based on the context of the knowledge structures being entered. This approach not only facilitates the creation of the rules base knowledge, but also frequently prevents the user from entering invalid values or logic structures. Also, the guided editing approach allows the developer to learn and use the system much more quickly, thus becoming productive much sooner.Type: GrantFiled: June 15, 1989Date of Patent: January 2, 1990Assignee: International Business Machines CorporationInventors: Andrew G. Derr, Charles A. McLaughlin
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Patent number: 4683196Abstract: The subject invention provides a means for the immunological detection of an entire class of microorganisms in clinical samples. The detection is accomplished by reaction of the clinical sample iwth a class-specific immunological reagent. This reagent is an antiserum either monoclonal or polyclonal in nature, and the detection is based upon reaction of the antiserum with an antigenic determinant which is shared among all members of the detectable class of microorganisms. The presence of the resulting immunological reaction product (e.g. the antigen-antibody complex) may be detected by well-known immunological detection-systems.Type: GrantFiled: March 16, 1984Date of Patent: July 28, 1987Assignee: Meru, Inc.Inventor: Charles A. McLaughlin