Patents by Inventor Charles A. R. Baxter

Charles A. R. Baxter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-Aminophenylacetamido-.DELTA..sup.3 -cephem antibacterial agents and method of use
    Patent number: 4183925
    Abstract: A series of novel 7-(D-.alpha.-aminophenylacetamido)- and 7-(D-.alpha.-hydroxyphenylacetamido)-.DELTA..sup.3 -cephem derivatives have been prepared wherein a heterocyclic thiomethyl moiety is located at the 3-position of the molecule. These compounds are useful as antibacterial agents for the treatment of diseases caused by Gram-positive and Gram-negative bacteria. Preferred members include 7-(D-.alpha.-hydroxyphenylacetamido)-3-(3-carbamoyl-1,2,4-triazol-5-yl)thi omethylceph-3-em-4-carboxylic acid and 7-(D-.alpha.-hydroxyphenylacetamido)-3-(2-carboxymethoxy-methyl-1,3,4-thia diazol-5-yl)thiomethylceph-3-em-4-carboxylic acid. Alternative methods of preparation are provided for these compounds, including various synthetic routes leading to the required novel heterocyclic thiol intermediates.
    Type: Grant
    Filed: October 21, 1977
    Date of Patent: January 15, 1980
    Assignee: Pfizer Inc.
    Inventors: Charles A. R. Baxter, Braham Shroot
  • Substituted mercaptothiadiazole compounds
    Patent number: 4144240
    Abstract: A series of novel 7-(D-.alpha.-aminophenylacetamido)- and 7-(D-.alpha.-hydroxyphenylacetamido)-.DELTA..sup.3 -cephem derivatives have been prepared wherein a heterocyclic thiomethyl moiety is located at the 3-position of the molecule. These compounds are useful as antibacterial agents for the treatment of diseases caused by Gram-positive and Gram-negative bacteria. Preferred members include 7-(D-.alpha.-hydroxyphenylacetamido)-3-(3-carbamoyl-1,2,4-triazol-5-yl)thi omethylceph-3-em-4-carboxylic acid and 7-(D-.alpha.-hydroxyphenylacetamido)-3-(2-carboxymethoxy-methyl-1,3,4-thia diazol-5-yl)thiomethylceph-3-em-4-carboxylic acid. Alternative methods of preparation are provided for these compounds, including various synthetic routes leading to the required novel heterocyclic thiol intermediates.
    Type: Grant
    Filed: September 16, 1977
    Date of Patent: March 13, 1979
    Assignee: Pfizer Inc.
    Inventors: Charles A. R. Baxter, Braham Shroot
  • Imidazo[2,1-b]thiazole and thiazolo[3,2-a]benzimidazole quaternary salts as hypoglycemic agents and growth promotants
    Patent number: 4080339
    Abstract: 7-Substituted imidazo[2,1-b]thiazolium and 9-substitutedthiazolo[3,2-a]benzimidazolium salts as blood-sugar lowering agents and growth promotants.
    Type: Grant
    Filed: January 12, 1977
    Date of Patent: March 21, 1978
    Assignee: Pfizer Inc.
    Inventors: Richard M. Acheson, John K. Stubbs, Charles A. R. Baxter, Donald E. Kuhla
  • Imidazo[2,1-b]thiazole and thiazolo[3,2-a]-benzimidazole quaternary salts as hypoglycemic agents and growth promotants
    Patent number: 4042583
    Abstract: 7-Substituted imidazo[2,1-b]thiazolium and 9-substitutedthiazolo[3,2-a]benzimidazolium salts as blood-sugar lowering agents and growth promotants.
    Type: Grant
    Filed: June 9, 1976
    Date of Patent: August 16, 1977
    Assignee: Pfizer Inc.
    Inventors: Richard M. Acheson, John K. Stubbs, Charles A. R. Baxter, Donald E. Kuhla
  • Imidazo[2,1-b]thiazole and thiazolo[3,2-a]-benzimidazole quaternary salts as hypoglycemic agents and growth promotants
    Patent number: 4008245
    Abstract: 7-Substituted imidazo[2,1-b]thiazolium and 9-substituted thiazolo-[3,2-a]benzimidazolium salts as blood-sugar lowering agents and growth promotants.
    Type: Grant
    Filed: July 8, 1975
    Date of Patent: February 15, 1977
    Assignee: Pfizer Inc.
    Inventors: Richard M. Acheson, John K. Stubbs, Charles A. R. Baxter, Donald E. Kuhla
  • Imidazo[2,1-b]thiazole and thiazolo[3,2-a]-benzimidazole quaternary salts as hypoglycemic agents and growth promotants
    Patent number: 3954784
    Abstract: 7-Substituted imidazo[2,1-b]thiazolium and 9-substitutedthiazolo-[3,2-a]benzimidazolium salts as blood-sugar lowering agents and growth promotants.
    Type: Grant
    Filed: September 19, 1974
    Date of Patent: May 4, 1976
    Assignee: Pfizer Inc.
    Inventors: Richard M. Acheson, John K. Stubbs, Charles A. R. Baxter, Donald E. Kuhla