Abstract: This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting and analyzing blood cells in biological samples. A small measured quantity of a biological sample, such as whole blood, is placed in a mixing bowl on the disposable test cartridge after being inserted into the cell analyzer. The analayzer also deposits a known amount of diluent/stain in the mixing bowl and mixes it with the blood. The analyzer takes a measured amount of the mixture and dispenses in a sample cup on the cartridge in fluid communication with an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping as it is transferred into the imaging chamber by the analyzer. Images of all of the cellular components within the imaging chamber are counted and analyzed to obtain a complete blood count.

Abstract: A magnetic connection can be formed between a magnet set of a first device and magnet set of a second device. The magnetic strength of the magnetic connection can be modified by changing an orientation of a magnet set of a first device from a first orientation to a second orientation. The magnet set or a case in which the magnet set is disposed can be asymmetric, such that alternating between the first and second orientations results in different magnetic connections.

Abstract: An interstitial fluid removal device including a first needle, a second needle, a fluid injector and an interstitial fluid extractor. The first needle is configured for insertion in a tissue of a multicellular organism to provide a fluid inlet channel. The second needle is configured for insertion in a tissue of a multicellular organism to provide an interstitial fluid outlet channel. The fluid injector is arranged in fluid communication with both a fluid source and the first needle and configured to inject a fluid in the tissue of the multicellular organism. The fluid extractor is arranged in fluid communication with the second needle and configured to extract interstitial fluid from the tissue of the multicellular organism. The fluid injector and the fluid extractor are independently and/or simultaneously operable with respect to each other.

Abstract: The present invention concerns a cooling device and method of forming and regenerating same for use in keeping perishable products cool. The cooling device includes a porous substrate that has been soaked in a first composition including at least one anti-freeze agent before being soaked in a second composition including at least one crosslinking agent and be exposed to UV irradiation. The cooling device further includes a substrate cover for sealingly covering the porous substrate after being soaked in the second composition and exposed to the UV irradiation. Prior to use, the cooling device is cooled to a desired temperature and exposed to further UV irradiation.

Abstract: Disclosed in one aspect is a method for performing a complete blood count (CBC) on a sample of whole blood by metering a predetermined amount of the whole blood and mixing it with a predetermined amount of diluent and stain and transferring a portion thereof to an imaging chamber of fixed dimensions and utilizing an automated microscope with digital camera and cell counting and recognition software to count every white blood cell and red blood corpuscle and platelet in the sample diluent/stain mixture to determine the number of red cells, white cells, and platelets per unit volume, and analyzing the white cells with cell recognition software to classify them.

Abstract: This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting blood cells in biological samples. A small unmeasured quantity of a biological sample such as whole blood is placed in the disposable test cartridge which is then inserted into the cell analyzer. The analyzer isolates a precise volume of the biological sample, mixes it with self-contained reagents and transfers the entire volume to an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping, when it is transferred into the imaging chamber. Images of essentially all of the cellular components within the imaging chamber are analyzed to obtain counts per unit volume.

Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.

Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.

Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.

Abstract: A robotic handling apparatus includes a first arm member configured to pivot about a first pivot axis and a first drive unit configured to bring the first arm member into motion about the first pivot axis. A second arm member is configured to pivot about a second pivot axis, the second arm member being connected to the first arm member and having a distal end portion. A second drive unit is configured to bring the second arm member into motion about the second pivot axis. A third arm member is configured to pivot about a third pivot axis. A carrier unit is connected to the distal end portion of the second arm member and the distal end of the third arm member to define a distance.

Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.

Abstract: Disclosed is a method of synchronising an image sensor with a PWM driver operable to drive an arrangement associated with the image sensor, wherein at least one synchronisation signal produced by the image sensor is used to reset the PWM driver and the at least one synchronisation signal is delayed before being used to reset the PWM driver such that the switching on or off of the at least one synchronisation signal occurs at a defined time in relation to a sensitive period of the image sensor's operation.

Abstract: The invention relates to a hydraulic actuator comprising a cylinder (1) in which a piston (2) secured to a rod (4) is mounted so as to slide in a sealed manner in order to delimit in the cylinder a hydraulic extension chamber (5) and a hydraulic retraction chamber (6) that are connected to respective ports, the hydraulic actuator comprising means for slowing the piston when the piston approaches a retracted position. According to the invention, the slowing means comprise first and second hydraulic lines (7, 8) extending between the extension port and the extension chamber, the first hydraulic line comprising a seat (13) while the piston bears a retractable finger (10) having an end (14) that comes to bear against the seat in order to close the first hydraulic line (7) when the piston approaches the retracted position, such that only the second hydraulic line (8) remains open while the piston completes its travel towards the retracted position. Landing gear and aircraft comprising such an actuator.

Abstract: An implantable medical device, including a magnet and a body encompassing the magnet, wherein the implantable medical device includes structural components in the body configured to move away from one another upon initial rotation of the magnet relative to the body when the magnet is subjected to an externally generated magnetic field, thereby limiting rotation of the magnet beyond the initial rotation.

Abstract: A magnetic alignment system that can form part of a cochlear implant system. The magnetic alignment system prevents substantial movement of a magnet of an implanted component during an MRI procedure or allows for easy removal of the magnet to facilitate the MRI procedure.

Abstract: An implantable medical device, including a magnet and a body encompassing the magnet, wherein the implantable medical device includes structural components in the body configured to move away from one another upon initial rotation of the magnet relative to the body when the magnet is subjected to an externally generated magnetic field, thereby limiting rotation of the magnet beyond the initial rotation.

Abstract: A method for absolute protein or peptide quantitation by mass spectroscopy. A sample containing a protein or peptide of interest is prepared for mass spectroscopy analysis. The sample is subjected to mass spectroscopy analysis at low resolution whereby a single additive mass spectroscopy peak is obtained, then is subjected to high resolution mass spectroscopy analysis whereby a plurality of mass spectroscopy peaks are obtained. The intensity of each of the plurality of mass spectroscopy peaks is quantitated either by comparison to an internal standard set, or by using a standard curve generated for each isotopologue set. Quantitation using a standard curve enhances quantitation across a dynamic range of analyte.

Abstract: A magnetic alignment system that can form part of a cochlear implant system. The magnetic alignment system prevents substantial movement of a magnet of an implanted component during an MRI procedure or allows for easy removal of the magnet to facilitate the MRI procedure.

Abstract: Systems and methods are described for managing articles. The systems and methods described herein may comprise an example method for manufacturing an article. The systems and methods described herein may comprise an example method for cutting and registration of an article. The systems and methods provides an end-to-end manufacturing value chain as a closed system and feedback loop.

Abstract: A magnetic alignment system that can form part of a cochlear implant system. The magnetic alignment system prevents substantial movement of a magnet of an implanted component during an MRI procedure or allows for easy removal of the magnet to facilitate the MRI procedure.