Patents by Inventor Charles A. Sherman

Charles A. Sherman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized cefuroxime axetil
    Publication number: 20030017214
    Abstract: Solid pharmaceutical compositions comprising cefuroxime axetil as active ingredient and a zinc salt as stabilizer.
    Type: Application
    Filed: September 12, 2002
    Publication date: January 23, 2003
    Inventor: Bernard Charles Sherman
  • Microfabricated recessed disk microelectrodes: characterization in static and convective solutions
    Publication number: 20030015422
    Abstract: Construction and characterization of microfabricated recessed disk microelectrodes (RDMs) of 14 and 55 &mgr;m diameter are reported. The work reported here makes several new contributions to the current literature on microfabricated RDMs. Hybrid blamers were constructed by fusion of vesicles of dimyristoylphosphatidyl choline (DMPC), which forms the top layer, with ethanol-rinsed SAMs of hexadecanethiol on gold, which form the bottom layer. Gramicidin A was included in the modifying solutions to incorporate it into hybrid blamers.
    Type: Application
    Filed: March 22, 2002
    Publication date: January 23, 2003
    Inventors: Ingrid Fritsch, Charles Sherman Henry, Benjamin P. Bowen, Walter Vandaveer, Nicole Bratcher
  • Benazepril Hydrochloride tablet formulations
    Publication number: 20020183308
    Abstract: Stable tablets comprising benazepril hydrochloride are prepared by employing zinc stearate as the lubricant.
    Type: Application
    Filed: April 12, 2002
    Publication date: December 5, 2002
    Inventor: Bernard Charles Sherman
  • Stabilized cefuroxime axetil
    Patent number: 6485744
    Abstract: Solid pharmaceutical compositions comprising cefuroxime axetil as active ingredient and a zinc salt as stabilizer.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: November 26, 2002
    Inventor: Bernard Charles Sherman
  • Fosinopril sodium tablet formulation
    Publication number: 20020131999
    Abstract: Stable tablets comprising fosinopril sodium are prepared by employing either stearic acid or zinc stearate as the lubricant.
    Type: Application
    Filed: January 11, 2002
    Publication date: September 19, 2002
    Inventor: Bernard Charles Sherman
  • Pharmaceutical composition comprising fenofibrate
    Patent number: 6444225
    Abstract: The bioavailability of fenofibrate is improved by making a solid dispersion of a disentegrant in the fenofibrate. Method of making said solid dispersion comprising melting the fenofibrate, blending the disintegrant into the melt, and resolidifying the mixture.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: September 3, 2002
    Inventor: Bernard Charles Sherman
  • Pharmaceutical compositions comprising moexipril magnesium
    Publication number: 20020037858
    Abstract: Stable solid compositions comprising moxeipril magnesium can be made using moexipril or an acid addition salt thereof, by reacting the moxeipril or acid addition salt with an alkaline magnesium compound in the presence of a solvent, so as to convert most or all of the moexipril or acid addition salt to moexipril magnesium.
    Type: Application
    Filed: March 16, 2001
    Publication date: March 28, 2002
    Inventor: Bernard Charles Sherman
  • Antifungal solutions
    Patent number: 6340698
    Abstract: A solution for oral administration comprising intraconazole or saperconazole, an acid, an alcoholic co-solvent.
    Type: Grant
    Filed: November 24, 2000
    Date of Patent: January 22, 2002
    Inventor: Bernard Charles Sherman
  • Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride
    Publication number: 20010027178
    Abstract: A pharmaceutical composition in the form of an emulsion preconcentrate comprising a cyclosporin dissolved in a solvent system comprising acetylated monoglycerides, a hydrophilic organic solvent and a surfactant.
    Type: Application
    Filed: February 16, 2001
    Publication date: October 4, 2001
    Inventor: Bernard Charles Sherman
  • Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride
    Patent number: 6258783
    Abstract: Pharmaceutical compositions in the form of an emulsion preconcentrate or microemulsion preconcentrate which comprise a cyclosporin as active ingredient, acetylated monoglyceride as lipophilic solvent, a surfactant, and optionally a hydrophilic solvent.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: July 10, 2001
    Inventor: Bernard Charles Sherman
  • Solid pharmaceutical compositions comprising a cyclosporin and an anionic surfactant
    Patent number: 6197335
    Abstract: A solid pharmaceutical composition for oral administration comprising a cyclosporin and an anionic surfactant, preferably sodium lauryl sulfate, wherein the amount of anionic surfactant is at least about forty percent of the minimum amount needed to dissolve the cyclosporin in water.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: March 6, 2001
    Inventor: Bernard Charles Sherman
  • Pharmaceutical composition comprising bupropion hydrochloride and fumaric acid
    Patent number: 6194002
    Abstract: A pharmaceutical composition in solid dosage form comprising bupropion hydrochloride as active drug and fumaric acid as stabilizer.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: February 27, 2001
    Inventor: Bernarad Charles Sherman
  • Emulsion preconcentrate comprising a cyclosporin, propylene carbonate, and glycerides
    Patent number: 6159933
    Abstract: Pharmaceutical compositions in the form of an emulsion preconcentrate or microemulsion preconcentrate which comprise a cyclosporin as active ingredient, propylene carbonate as hydrophilic solvent, glycerides as lipophilic solvent, and a surfactant.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: December 12, 2000
    Inventor: Bernard Charles Sherman
  • Extended-release solid oral dosage forms of drugs having low solubility in water
    Patent number: 6132772
    Abstract: The present invention relates to extended-release solid oral dosage forms of a drug having low solubility in water are obtained by dissolving the drug in polyethylene glycol having a mean molecular weight of at least 1000 and adding thereto a hydrophilic gel-forming polymer.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: October 17, 2000
    Inventor: Bernard Charles Sherman
  • Solid substances comprising valproic acid and sodium valproate
    Patent number: 6077542
    Abstract: Substances that are solid at 25.degree. C. are obtained by dissolving sodium valproate in heated valproic acid and cooling the resultant solution. The resulting solid substances can easily be processed into solid pharmaceutical dosage forms.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: June 20, 2000
    Inventor: Bernard Charles Sherman
  • Microemulsion preconcentrates comprising cyclosporins
    Patent number: 5998365
    Abstract: A pharmaceutical composition in the form of a microemulsion preconcentrate comprising a cyclosporin dissolved in a solvent system further comprising a hydrophobic component, a hydrophilic component, and a surfactant, wherein either the hydrophobic component is selected from tocol, tocopherols, tocotrienols, and derivatives thereof, or the hydrophilic component is selected from propylene carbonate or polyethylene glycol having an average molecular weight of less than 1000.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: December 7, 1999
    Assignee: Bernard C. Sherman
    Inventor: Bernard Charles Sherman
  • Diltiazem hydrochloride formulation
    Patent number: 5968552
    Abstract: The invention relates to a pharmaceutical formulation comprising diltiazem hydrochloride. The formulation is in the form of a mixture of beads blended so as to provide a dissolution profile that renders the formulation suitable for oral administration once daily.
    Type: Grant
    Filed: June 2, 1997
    Date of Patent: October 19, 1999
    Inventor: Bernard Charles Sherman
  • Controlled-release pharmaceutical compositions
    Patent number: 5879714
    Abstract: A controlled-release pharmaceutical composition for oral administration comprising a multitude of granules made by dissolving or dispersing a drug and a water-insoluble polymer in a molten carrier, solidifying the resultant material, and grinding the resultant solid into granules.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: March 9, 1999
    Assignee: Bernard Charles Sherman
    Inventor: Bernard Charles Sherman
  • Slidably adjustable rigid awning
    Patent number: 5873202
    Abstract: The invention is an improved rigid awning structure which permits some regulation of pass-through light and which may be constructed attached to a building or free standing. The invention provides slated louver sets arranged one above the other in banks of at least two sets. At least one of the louver sets in each bank is slidably movable to achieve the regulation of pass through-light. The invention may be constructed utilizing many conventional frame building methods and materials.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: February 23, 1999
    Inventor: Charles Sherman Parks
  • Stable solid formulation of enalapril salt and process for preparation thereof
    Patent number: 5690962
    Abstract: There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of:i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and waterii) drying the wet mass, and;iii) further processing the resultant dried mass into tablets.When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: November 25, 1997
    Assignee: Apotex Corporation
    Inventor: Bernard Charles Sherman