Patents by Inventor Charles Baroud

Charles Baroud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220252519
    Abstract: A microfluidic device that includes at least one capillary trap and at least one microdrop having a sol-gel matrix. The microdrop is trapped in the capillary trap.
    Type: Application
    Filed: July 3, 2020
    Publication date: August 11, 2022
    Inventors: Laurent MUGHERLI, Charles BAROUD, Raphael TOMASl
  • Publication number: 20220010363
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Application
    Filed: July 19, 2021
    Publication date: January 13, 2022
    Inventors: Charles BAROUD, Rémi DANGLA, Paul ABBYAD, Silvan TURKCAN
  • Patent number: 11179722
    Abstract: Method for handling at least one first microdrop and at least one second microdrop in a microfluidic system including a capillary trap that has a first trapping zone and a second trapping zone, the method including steps consisting of: (i) trapping the first microdrop in the first trapping zone, and (ii) trapping the second microdrop in the second trapping zone, the first and the second trapping zone being arranged such that the first and the second microdrops are in contact with each other, the first and the second trapping zones being adapted such that the trapping forces returned to one of the microdrops are different.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: November 23, 2021
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Raphaël Tomasi
  • Patent number: 11066699
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: July 20, 2021
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RESCHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Patent number: 10710077
    Abstract: A method for handling, in a microfluidic system, microdrops which include samples, including the steps of forming, in an oil, microdrops of an aqueous solution containing a sample, the oil and/or the aqueous solution containing a sample including a gelling agent; trapping the microdrops by means of surface-tension traps pre-arranged in a trapping area; and at least partially gelling the oil in the trapping area and/or at least partially gelling the trapped microdrops.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: July 14, 2020
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Gabriel Amselem, Sébastien Sart, Raphaël Tomasi
  • Publication number: 20200190559
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Application
    Filed: December 9, 2019
    Publication date: June 18, 2020
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Publication number: 20200038867
    Abstract: Method for handling at least one first microdrop and at least one second microdrop in a microfluidic system including a capillary trap that has a first trapping zone and a second trapping zone, the method including steps consisting of: (i) trapping the first microdrop in the first trapping zone, and (ii) trapping the second microdrop in the second trapping zone, the first and the second trapping zone being arranged such that the first and the second microdrops are in contact with each other, the first and the second trapping zones being adapted such that the trapping forces returned to one of the microdrops are different.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 6, 2020
    Applicants: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles BAROUD, Raphaël TOMASI
  • Patent number: 10501789
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: December 10, 2019
    Assignees: École Polytechnique, Centre national de la recherche scientifique
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Patent number: 9943843
    Abstract: The subject of the present invention is a microfluidic circuit in which are defined microchannels able to contain fluids and including at least one device for forming drops of a solution, guiding the drops to a storage zone in which one of the drops can be brought into contact with a drop of another solution, the walls of the microchannel portion forming the first drop-formation device diverging so as to cause drops of the first solution to detach under the effect of the surface tension of the first solution; the first guide include wall portions of the microchannels that diverge so as to cause the drops to move along under the effect of the surface tension of the first solution.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: April 17, 2018
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Paul Abbyad, Etienne Fradet, Rémi Dangla
  • Publication number: 20180037934
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Application
    Filed: October 18, 2017
    Publication date: February 8, 2018
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Patent number: 9816133
    Abstract: Provided herein are microfluidic circuits that include at least one device for forming a quantity of drops of a solution in a carrier fluid and at least one storage zone for storing drops produced by the microfluidic device. Such microfluidic circuits are useful, for example, for the analysis of a solution containing a biological sample.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: November 14, 2017
    Assignees: École Polytechnique, Centre national de la recherche scientifique
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Publication number: 20170252744
    Abstract: A method for handling, in a microfluidic system, microdrops which include samples, including the steps of forming, in an oil, microdrops of an aqueous solution containing a sample, the oil and/or the aqueous solution containing a sample including a gelling agent; trapping the microdrops by means of surface-tension traps pre-arranged in a trapping area; and at least partially gelling the oil in the trapping area and/or at least partially gelling the trapped microdrops.
    Type: Application
    Filed: October 17, 2014
    Publication date: September 7, 2017
    Applicants: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles BAROUD, Gabriel AMSELEM, Sébastien SART, Raphaël TOMASI
  • Patent number: 9452432
    Abstract: The invention relates to a microfluidic circuit including at least one microchannel for the flow of a first fluid conveying drops or bubbles of at least one second fluid, characterized in that the height of the microchannel is sized so as to crush the drops or bubbles during the movement thereof, and in that the microchannel comprises at least one trough, extending at least partially in the direction of flow of the first fluid or an area for trapping drops or bubbles, said area or the trough having a height that is greater than the height of the microchannel, such that at least some of the drops or bubbles of the second fluid in the microchannel are drawn and guided into the trough or into the trapping area.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: September 27, 2016
    Assignees: ECOLE POLYTECHNIQUE, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Rémi Dangla, Francois Gallaire
  • Publication number: 20150267246
    Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zone(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 24, 2015
    Inventors: Charles Baroud, Remi Dangla, Paul Abbyad, Silvan Turkcan
  • Publication number: 20150258543
    Abstract: The subject of the present invention is a microfluidic circuit in which are defined microchannels able to contain fluids and including at least one device for forming drops of a solution, guiding the drops to a storage zone in which one of the drops can be brought into contact with a drop of another solution, the walls of the microchannel portion forming the first drop-formation device diverging so as to cause drops of the first solution to detach under the effect of the surface tension of the first solution; the first guide include wall portions of the microchannels that diverge so as to cause the drops to move along under the effect of the surface tension of the first solution.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 17, 2015
    Inventors: Charles Baroud, Paul Abbyad, Etienne Fradet, Rémi Dangla
  • Patent number: 9133009
    Abstract: The invention relates to a device (1) for forming droplets in a microfluidic circuit, the device comprising a chamber (3) containing a first fluid and defined by two opposite walls (10, 11) that diverge relative to each other in at least one given direction, and a microchannel (8) containing a second fluid and leading into a zone of said chamber (3) that is upstream relative to the given direction, the outlet of the microchannel (8) into the chamber (3) constituting an enlargement in the flow section for the second fluid, and the enlargement giving rise to droplets (14) of the second fluid forming within the first fluid.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: September 15, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE POLYTECHNIQUE
    Inventors: Charles Baroud, Rémi Dangla
  • Publication number: 20130078164
    Abstract: The invention relates to a device (1) for forming droplets in a microfluidic circuit, the device comprising a chamber (3) containing a first fluid and defined by two opposite walls (10, 11) that diverge relative to each other in at least one given direction, and a microchannel (8) containing a second fluid and leading into a zone of said chamber (3) that is upstream relative to the given direction, the outlet of the microchannel (8) into the chamber (3) constituting an enlargement in the flow section for the second fluid, and the enlargement giving rise to droplets (14) of the second fluid forming within the first fluid.
    Type: Application
    Filed: March 28, 2011
    Publication date: March 28, 2013
    Applicant: ECOLE POLYTECHNIQUE
    Inventors: Charles Baroud, Rémi Dangla
  • Publication number: 20120315203
    Abstract: The invention relates to a microfluidic circuit including at least one microchannel for the flow of a first fluid conveying drops or bubbles of at least one second fluid, characterised in that the height of the microchannel is sized so as to crush the drops or bubbles during the movement thereof, and in that the microchannel comprises at least one trough, extending at least partially in the direction of flow of the first fluid or an area for trapping drops or bubbles, said area or the trough having a height that is greater than the height of the microchannel, such that at least some of the drops or bubbles of the second fluid in the microchannel are drawn and guided into the trough or into the trapping area.
    Type: Application
    Filed: September 29, 2010
    Publication date: December 13, 2012
    Inventors: Charles Baroud, Rémi Dangla, Francois Gallaire
  • Patent number: 8136553
    Abstract: A microfluidic circuit comprising microchannels (24, 26) containing different fluids (F1, F2), with a laser beam being focused at (32) on an interface (30) between the fluids so as to form a pump, a valve, or a mixer, for example.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: March 20, 2012
    Assignees: Centre National de la Recherche Scientifique, Ecole Polytechnique
    Inventors: Charles Baroud, Jean-Pierre Delville, Régis Wunenburger, Patrick Huerre
  • Publication number: 20080196778
    Abstract: A microfluidic circuit comprising microchannels (24, 26) containing different fluids (F1, F2), with a laser beam being focused at (32) on an interface (30) between the fluids so as to form a pump, a valve, or a mixer, for example.
    Type: Application
    Filed: July 7, 2005
    Publication date: August 21, 2008
    Inventors: Charles Baroud, Jean-Pierre Delville, Regis Wunenburger, Patrick Huerre