Patents by Inventor Charles Bell

Charles Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260022130
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: February 28, 2025
    Publication date: January 22, 2026
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Marius Daniel Rinaldo LUTZ, Fionn O'HARA, Hans RICHTER, Martin RITTER, Didier ROMBACH, Martin KURATLI
  • Publication number: 20250339862
    Abstract: A mill housing of a pulverizer system. The mill housing may include a cutting chamber, and a plurality of air intake holes configured to introduce airflow into and in a direction tangential to the cutting chamber. The plurality of air intake holes may include two or more single air intake holes, two or more single air intake slots, or one or more groupings of air intake holes, spaced evenly around an exterior surface of the mill housing. Each of the one or more groupings of air intake holes may include two or more vertically aligned air intake holes. The holes, slots, or groupings of holes may be machined into the mill housing exterior at an angle so as to allow the intake of air to enter the mill housing tangentially to the circumference of the cutting chamber, resulting in a more polished particulate having a higher density and increased flowability.
    Type: Application
    Filed: April 30, 2025
    Publication date: November 6, 2025
    Inventors: Alisha Konst, Charles Bell
  • Patent number: 12281124
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Grant
    Filed: September 26, 2023
    Date of Patent: April 22, 2025
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Charles Bell, Joerg Benz, Luca Gobbi, Uwe Grether, Katrin Groebke Zbinden, Benoit Hornsperger, Buelent Kocer, Carsten Kroll, Bernd Kuhn, Marius Daniel Rinaldo Lutz, Fionn O'Hara, Hans Richter, Martin Ritter, Didier Rombach, Martin Kuratli
  • Publication number: 20240150373
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: September 26, 2023
    Publication date: May 9, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Marius Daniel Rinaldo LUTZ, Fionn O'HARA, Hans RICHTER, Martin RITTER, Didier ROMBACH, Martin KURATLI
  • Patent number: 11802133
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: October 31, 2023
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Charles Bell, Joerg Benz, Luca Gobbi, Uwe Grether, Katrin Groebke Zbinden, Benoit Hornsperger, Buelent Kocer, Carsten Kroll, Bernd Kuhn, Marius Daniel Rinaldo Lutz, Fionn O'Hara, Hans Richter, Martin Ritter, Didier Rombach, Martin Kuratli
  • Publication number: 20230271094
    Abstract: The present invention relates to system, vehicle and method for providing an amusement activity. According to one embodiment, it is provided an amusement vehicle adapted for carrying a passenger, the vehicle comprising of a wireless signal receiver, a trigger mechanism and amusement means, a wireless signal transmitter capable of transmitting a signal to said amusement vehicle, the signal defining a trigger mechanism, an amusement scene and a proximity context, wherein the wireless signal transmitter transmits a signal to a vehicle in an amusement path, the vehicle receives the signal comprising a trigger mechanism and amusement scene and determines the amusement means based on received amusement scene, determines the trigger mechanism based on received trigger mechanism and triggers an amusement means to perform an amusement scene.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 31, 2023
    Inventors: Charles Bell, Clifford Black, JR.
  • Publication number: 20230183224
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1, R2 and R3 are as described herein, pharmaceutically acceptable salts thereof, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: November 22, 2022
    Publication date: June 15, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Uwe GRETHER, Benoit HORNSPERGER, Buelent KOCER, Bernd KUHN, Hans RICHTER, Satoshi TSUCHIYA
  • Publication number: 20230117324
    Abstract: The invention provides new heterocyclic compounds having the general formula (Ic) wherein A, L, X, m, n and R20 to R23 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: August 9, 2022
    Publication date: April 20, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Dennis Jul HANSEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Fionn O'HARA, Hans RICHTER, Martin RITTER, Satoshi TSUCHIYA, Rui CHEN
  • Publication number: 20230050901
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: May 20, 2022
    Publication date: February 16, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Marius Daniel Rinaldo LUTZ, Fionn O'HARA, Hans RICHTER, Martin RITTER, Didier ROMBACH, Martin KURATLI
  • Patent number: 11420961
    Abstract: The invention provides new heterocyclic compounds having the general formula (IA) wherein A, L, X, Y, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: August 23, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joerg Benz, Uwe Grether, Benoit Hornsperger, Buelent Kocer, Bernd Kuhn, Hans Richter, Satoshi Tsuchiya, Charles Bell, Xiang Wu, Xiaofei Yan, Luca Gobbi
  • Patent number: 11390610
    Abstract: The invention provides new heterocyclic compounds having the general Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, X, Y1 and Y2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: July 19, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joerg Benz, Uwe Grether, Benoit Hornsperger, Bernd Kuhn, Hans Richter, Buelent Kocer, Fionn O'Hara, Martin Ritter, Satoshi Tsuchiya, Ludovic Collin, Simon E. Johnson, Charles Bell
  • Publication number: 20210107920
    Abstract: The invention provides new heterocyclic compounds having the general formula (Ic) wherein A, L, X, m, n and R20 to R23 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: September 18, 2020
    Publication date: April 15, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Dennis Jul HANSEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Fionn O'HARA, Hans RICHTER, Martin RITTER, Satoshi TSUCHIYA, Rui CHEN
  • Patent number: 10977518
    Abstract: Techniques for generating and utilizing machine learning based adaptive instructions for annotation are described. An annotation service can use models to identify edge case data elements predicted to elicit differing annotations from annotators, “bad” data elements predicted to be difficult to annotate, and/or “good” data elements predicted to elicit matching or otherwise high-quality annotations from annotators. These sets of data elements can be automatically incorporated into annotation job instructions provided to annotators, resulting in improved overall annotation results via having efficiently and effectively “trained” the annotators how to perform the annotation task.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: April 13, 2021
    Assignee: Amazon Technologies, Inc.
    Inventors: Rahul Sharma, Vikram Madan, James Robert Blair, Charles Bell
  • Publication number: 20200392125
    Abstract: The invention provides new heterocyclic compounds having the general formula (IA) wherein A, L, X, Y, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: May 27, 2020
    Publication date: December 17, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg BENZ, Uwe GRETHER, Benoit HORNSPERGER, Buelent KOCER, Bernd KUHN, Hans RICHTER, Satoshi TSUCHIYA, Charles BELL, Xiang WU, Xiaofei YAN, Luca GOBBI
  • Publication number: 20200308190
    Abstract: The invention provides new heterocyclic compounds having the general formula wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: April 9, 2020
    Publication date: October 1, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Luca GOBBI, Uwe GRETHER, Katrin GROEBKE ZBINDEN, Benoit HORNSPERGER, Buelent KOCER, Carsten KROLL, Bernd KUHN, Marius Daniel Rinaldo LUTZ, Fionn O'HARA, Hans RICHTER, Martin RITTER, Didier ROMBACH, Martin KURATLI
  • Publication number: 20200308158
    Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1, R2 and R3 are as described herein, pharmaceutically acceptable salts thereof, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 1, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Charles BELL, Joerg BENZ, Uwe GRETHER, Benoit HORNSPERGER, Buelent KOCER, Bernd KUHN, Hans RICHTER, Satoshi TSUCHIYA
  • Publication number: 20200299277
    Abstract: The invention provides new heterocyclic compounds having the general Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, X, Y1 and Y2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: March 23, 2020
    Publication date: September 24, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg BENZ, Uwe GRETHER, Benoit HORNSPERGER, Bernd KUHN, Hans RICHTER, Buelent KOCER, Fionn O'HARA, Martin RITTER, Satoshi TSUCHIYA, Ludovic COLLIN, Simon E. JOHNSON, Charles BELL
  • Patent number: 9718177
    Abstract: Some embodiments of the present disclosure include a tool set for the installation and removal of a gasket from a hose. The tool set may include a gasket insertion tool configured to install a gasket on a hose, the gasket insertion tool being self-centering and having a plunger foot configured to install the gasket onto the hose. The tool set may also include a gasket removal tool configured to remove a gasket from a hose, the gasket removal tool being self-centering and including at least one blade configured to grab onto the gasket to remove the gasket from the hose.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: August 1, 2017
    Inventor: Charles Bell
  • Patent number: 8464516
    Abstract: An exhaust gas treatment device includes an inlet housing having an inlet opening for receipt of an exhaust flow from an engine aligned along a first axis. A main housing includes a cylindrical body portion defining a treatment zone and an exhaust outlet aligned along a second axis extending parallel to the first axis. The inlet housing is in fluid communication with and fixed to an outer surface of the main housing. The inlet housing includes a contoured wall including an end portion positioned opposite the inlet opening, an aperture extending through the wall transverse to the first axis, divergent side wall portions on opposite sides of the inlet opening, and a necked portion having a reduced cross-section positioned downstream of the inlet opening and upstream of the aperture. A component is coupled to the main housing for treating exhaust flowing through the treatment zone.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: June 18, 2013
    Assignee: Tenneco Automotive Operating Company Inc.
    Inventors: Charles Bell, Megan Wikaryasz, Douglas Otrompke
  • Publication number: 20120124982
    Abstract: An exhaust gas treatment device includes an inlet housing having an inlet opening for receipt of an exhaust flow from an engine aligned along a first axis. A main housing includes a cylindrical body portion defining a treatment zone and an exhaust outlet aligned along a second axis extending parallel to the first axis. The inlet housing is in fluid communication with and fixed to an outer surface of the main housing. The inlet housing includes a contoured wall including an end portion positioned opposite the inlet opening, an aperture extending through the wall transverse to the first axis, divergent side wall portions on opposite sides of the inlet opening, and a necked portion having a reduced cross-section positioned downstream of the inlet opening and upstream of the aperture. A component is coupled to the main housing for treating exhaust flowing through the treatment zone.
    Type: Application
    Filed: November 18, 2010
    Publication date: May 24, 2012
    Inventors: Charles Bell, Megan Wikaryasz, Douglas Otrompke