Patents by Inventor Charles Biddle

Charles Biddle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for assessing liver pathology
    Patent number: 12383191
    Abstract: In some aspects, the described systems and methods provide for a method for training a deep learning model to assess liver pathology, including accessing annotated liver pathology images associated with a group of patients in one or more randomized controlled clinical trials of nonalcoholic steatohepatitis therapy, each of the annotated liver pathology images including at least one annotation describing one or more tissue characteristic categories for a portion of the image, and training the deep learning model based on the annotated liver pathology images to predict the tissue characteristic categories, selected from a group comprising steatosis, lobular inflammation, hepatocyte ballooning, and fibrosis stage.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: August 12, 2025
    Assignee: PathAI, Inc.
    Inventors: Amaro N. Taylor-Weiner, Harsha Vardhan Pokkalla, Hunter L. Elliott, Benjamin P. Glass, Ilan N. Wapinski, Aditya Khosla, Murray Resnick, Michael C. Montalto, Andrew H. Beck, Zahil Shanis, Aryan Pedawi, Quang Huy Le, Jason K. Wang, Maryam Pouryahya, Kenneth Knute Leidal, Oscar M. Carrasco-Zevallos, Dinkar Juyal, Charles Biddle-Snead, Katy Wack
  • Resin transfer molding of centrifuge rotor
    Patent number: 6482342
    Abstract: A method for fabricating fiber-reinforced composite structures, including centrifuge rotors, by resin transfer molding (RTM) is disclosed. The method involves loading reinforcing fibers into a mold and then injecting resin into the mold to coat the fibers to form the composite structure. Two types of reinforcing fibers are used—fabric preforms at the surfaces of the structure and chopped fibers at the interior of the structure. Also disclosed is a fiber-reinforced composite structure comprising a skin layer of reinforcing fabric, chopped fibers distributed throughout the interior of the structure, and epoxy resin that binds the fabric and chopped fibers together into a fiber-reinforced composite structure. The resin transfer molding method is especially useful for fabricating composite centrifuge rotors.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: November 19, 2002
    Assignee: Composite Rotor, Inc.
    Inventors: Mohammad Ghassem Malekmadani, Charles Biddle, Hung Nguyen, Reza Sheikhrezai
  • Resin transfer molding of a centrifuge rotor
    Patent number: 5972264
    Abstract: A method for fabricating fiber-reinforced composite structures, including centrifuge rotors, by resin transfer molding (RTM) is disclosed. The method involves loading reinforcing fibers into a mold and then injecting resin into the mold to coat the fibers to form the composite structure. Two types of reinforcing fibers are used--fabric preforms at the surfaces of the structure and chopped fibers at the interior of the structure. Also disclosed is a fiber-reinforced composite structure comprising a skin layer of reinforcing fabric, chopped fibers distributed throughout the interior of the structure, and epoxy resin that binds the fabric and chopped fibers together into a fiber-reinforced composite structure. The resin transfer molding method is especially useful for fabricating composite centrifuge rotors.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: October 26, 1999
    Assignee: Composite Rotor, Inc.
    Inventors: Mohammad Ghassem Malekmadani, Charles Biddle, Hung Nguyen, Reza Sheikhrezai