Patents by Inventor Charles Bishop

Charles Bishop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210353667
    Abstract: The invention relates to products by processes, product compositions, product formulations and product uses that are all related to reduced ultrapure water cluster sizes in an aqueous composition containing a non-H2O substance in the reduced size water clusters in order to improve bioavailability of the aqueous composition. The invention processes use higher flow rate of the blended aqueous composition from a jet openings of a nozzle inside the hollow cylinder to reduce sizes of the ultrapure water clusters in the blended aqueous composition of the non-H2O substance to less than 300 nanometers.
    Type: Application
    Filed: July 27, 2021
    Publication date: November 18, 2021
    Inventors: Patrick Charles BISHOP, Sean Bryan GILL
  • Publication number: 20200121715
    Abstract: The invention relates to products by processes, product compositions, product formulations and product uses that are all related to reduced ultrapure water cluster sizes in an aqueous composition containing a non-H2O substance in the reduced size water clusters in order to improve bioavailability of the aqueous composition. The invention processes use higher flow rate of the blended aqueous composition from a jet openings of a nozzle inside the hollow cylinder to reduce sizes of the ultrapure water clusters in the blended aqueous composition of the non-H2O substance to less than 300 nanometers.
    Type: Application
    Filed: October 20, 2018
    Publication date: April 23, 2020
    Applicants: MC Technology Holdings, LLC, Hydrosome Labs, LLC
    Inventors: Patrick Charles Bishop, Sean Bryan Gill
  • Publication number: 20190383835
    Abstract: Methods and systems directed to monitoring for the presence or progression of amyloid diseases via detection of amyloid fibrils in a sample from an individual are disclosed. An individual, or sample from an individual, is treated with a reagent including a fluorescent protein. The fluorescent protein in the reagent binds to amyloid fibrils present in the sample. Detecting a signal from fluorescent protein bound to the treated sample indicates the presence of amyloid fibrils in the sample and possible diagnosis of an amyloid disease. The presence and progression of an amyloid disease is monitored by quantifying signal intensity from samples taken over time. Treatment with a reagent including a fluorescent protein inhibits amyloid fibril formation by providing the reagent to an environment including amyloid monomers. The fluorescent protein binds to amyloid oligomers during the lag phase and/or elongation phase of amyloid fibril formation, preventing formation of mature amyloid fibrils.
    Type: Application
    Filed: January 23, 2018
    Publication date: December 19, 2019
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: George I. MAKHATADZE, Changmingzi XU-FUERY, Josephine Grace LoRICCO, Nathan JAMES, Anthony Charles BISHOP
  • Publication number: 20190358169
    Abstract: The disclosure provides nanometer sized water clusters comprising or consisting essentially of ultrapure water that encapsulate a solute, wherein the water clusters have a median diameter of between about 2 to about 400 nanometers and uses thereof. Also provided by the disclosure are processes and methods for making nanosized water clusters, including processes and methods for encapsulating hydrated solutes in nanosized water clusters.
    Type: Application
    Filed: May 23, 2019
    Publication date: November 28, 2019
    Inventors: Patrick Charles BISHOP, Sean Bryan Gill
  • Patent number: 10300725
    Abstract: Some embodiments of a tally stamp device described herein provide a stamp and a counter system. The tally stamp may include an elongate body housing the stamp and counter system.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: May 28, 2019
    Inventor: Charles Bishop
  • Publication number: 20180009250
    Abstract: Some embodiments of a tally stamp device described herein provide a stamp and a counter system. The tally stamp may include an elongate body housing the stamp and counter system.
    Type: Application
    Filed: July 5, 2017
    Publication date: January 11, 2018
    Inventor: Charles Bishop
  • Publication number: 20100251961
    Abstract: Shaped metal deposition apparatus comprises a mounting head for mounting a shaped metal deposition device, an inert gas shield for providing an inert atmosphere around shaped metal deposited in use by the shaped metal deposition device, and a rotatable coupling between the mounting head and the inert gas shield to permit relative rotation therebetween.
    Type: Application
    Filed: October 28, 2008
    Publication date: October 7, 2010
    Applicant: Rolls-Royce PLC
    Inventor: Jeffrey Charles Bishop
  • Publication number: 20100077892
    Abstract: A forcing tool is provided in which a lobe aperture incorporates opposed lobe pairs having driving flanks. Distal ends of the driving flanks define a spacing consistent with the width of a dowel or tang to be utilized in a twisted-dowel joint. The aperture incorporates location recesses to allow the dowel or tang to pass through the aperture and then through twisting create a lock condition.
    Type: Application
    Filed: November 19, 2007
    Publication date: April 1, 2010
    Applicant: Rolls-Royce plc
    Inventor: Jeffrey Charles Bishop
  • Patent number: 7316094
    Abstract: The invention provides a fishing apparatus having a pivot arm mounted on a frame with a fishing line paid out on one end of the pivot arm via a flexible fishing rod and a hooking mechanism connected to the opposite end via a trigger line and a pull line. The hooking mechanism may resemble a mouse trap with a trigger connected to the trigger line arm a retaining arm engaging the trigger and retaining a spring-loaded arm in the set position. The spring-loaded arm is connected to the pull line. A fish trying to swim with the hook will cause the pivot arm to tip down, triggering the hooking mechanism. The spring-loaded arm pivots downward rapidly, pulling the pivot arm so that the fishing rod moves upward rapidly and sets the hook in the fish's mouth. The spring bias in the spring-loaded arm then keeps the fishing line under tension so that the fish doesn't release the hook without ripping the hook from the mouth.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: January 8, 2008
    Inventor: Kevin Charles Bishop
  • Publication number: 20070292209
    Abstract: Embodiments of the present invention include a stationary boat lift in which boats can enter and exit quite readily. The boat lift allows a boat to bypass various barriers in a safe and efficient manner by orienting the boat in a direction substantially parallel to the barrier, vertically lifting the boat out of one waterway, laterally translating the boat horizontally over the barrier, and then vertically lowering the boat into a second waterway.
    Type: Application
    Filed: October 11, 2006
    Publication date: December 20, 2007
    Inventors: Richard Bishop, charles Bishop
  • Publication number: 20070189649
    Abstract: Exemplary bearing cartridges are provided. An outer retaining member defines a first curved surface lined with a lubricant. An inner, carburized titanium member is received by the outer retaining member. The inner member defines a second curved surface in sliding contact with the first curved surface. A carburized case extends a predetermined distance from the second curved surface into the inner member. The bearing cartridge may be installed in a housing. The outer retaining member may include a ring defining a concave spherical surface. The inner member may include a ball defining a convex spherical surface. Alternately, the outer retaining member may include a bushing defining a concave cylindrical surface or a spherical ball defining a bore that defines a concave cylindrical surface and the inner member may include a pin defining a convex cylindrical surface. The lubricant may include a polytetrafluroethylene-based lubricant.
    Type: Application
    Filed: February 16, 2006
    Publication date: August 16, 2007
    Inventors: Morri Montazeri, Charles Bishop
  • Publication number: 20070144786
    Abstract: A connector is provided for selectively connecting or disconnecting a stripper rubber to or from drilling head equipment such as a bearing assembly. A generally cylindrical adapter connected to the equipment defines a primary bore accommodate a down hole tubular. One or more cam pin bores, adapted to house one or more cam pins, are positioned radially around the adapter substantially parallel to the primary bore. One or more cam lock bores adapted to house one or more at least partially rotatable cam locks, are offset from the pin cam bores such that each cam pin bore partially intersects a corresponding cam lock bore to form an apertaure through which the cam lock engages the cam pin. One or more cam pins are connected to the stripper rubber; and one or more at least partially rotatable cam locks house in the cam lock bores of the adapter optionally engage or disengage the pin cams to respectively connect or disconnect the stripper rubber to or from the equipment.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 28, 2007
    Inventors: John Williams, Charles Bishop
  • Publication number: 20070122477
    Abstract: A controlled-release pharmaceutical formulation including cholecalciferol and/or ergocalciferol, a method of making the formulation, and a method of administering the formulation to treat 25-hydroxyvitamin D insufficiency or deficiency, are disclosed. The composition and method of administration preferably result in delayed release of the vitamin(s) in the ileum of the small intestine and sustained, substantially constant, release of the vitamin(s) over an extended period, e.g., at least 4 hours or more. Individual and combined dosages of 500 IU to 50,000 IU per dosage form, preferably daily, are disclosed.
    Type: Application
    Filed: October 12, 2006
    Publication date: May 31, 2007
    Applicant: CYTOCHROMA, INC.
    Inventors: Charles Bishop, Keith Crawford, Eric Messner
  • Publication number: 20060211661
    Abstract: The invention provides 24-hydroxyvitamin D compounds and methods for their use in the treatment and prophylaxis of hyperparathyroidism and hyperproliferative diseases, and in the modulation of the immune and inflammatory responses as well as the treatment of bone depletive disorders.
    Type: Application
    Filed: June 2, 2006
    Publication date: September 21, 2006
    Applicant: Genzyme Corporation
    Inventors: Charles Bishop, Joyce Knutson, Stephen Strugnell
  • Publication number: 20060034851
    Abstract: The present invention is directed to a conjugate which includes at least one vitamin D moiety thereof and at least one targeting molecule moiety to pharmaceutical compositions of the conjugate, and to methods for using the conjugate for target-specific delivery of vitamin D or analogs thereof to tissues in need thereof. When a particularly preferred form is administered to a patient, the targeting molecule component of the conjugate of this invention seeks out and binds to a tissue of interest, such as bone or tumor tissue, where the vitamin D has a therapeutic effect.
    Type: Application
    Filed: August 25, 2005
    Publication date: February 16, 2006
    Applicant: Genzyme Corporation
    Inventors: Richard Mazess, Charles Bishop
  • Publication number: 20050239756
    Abstract: The present invention provides a method of increasing or maintaining blood concentrations of 1,25-dihydroxyvitamin D in a patient by administering an amount of 1?-hydroxyvitamin D2. The invention also provides a method of concurrently lowering or maintaining plasma intact parathyroid hormone levels, increasing or maintaining serum calcium levels, maintaining serum phosphorous levels, or increasing or maintaining serum 1,25-dihydroxyvitamin D levels in a human patient by administering to the patient an amount of 1?-hydroxyvitamin D2. The invention also provides a method of reducing the risk of over suppression of plasma intact parathyroid hormone levels in a patient undergoing treatment for elevated levels of plasma intact parathyroid hormone, by administering 1?-hydroxyvitamin D2 in an amount sufficient to decrease elevated intact parathyroid hormone levels while avoiding an abnormally low bone turnover rate.
    Type: Application
    Filed: April 25, 2005
    Publication date: October 27, 2005
    Applicant: Bone Care International, Inc.
    Inventors: Charles Bishop, Eric Messner, Keith Crawford
  • Publication number: 20050173127
    Abstract: A connector is provided for selectively connecting or disconnecting a stripper rubber to or from drilling head equipment such as a bearing assembly. A generally cylindrical adapter connected to the equipment defines a primary bore to accommodate a down hole tubular. One or more cam pin bores, adapted to house one ore more cam pins, are positioned radially around the adapter substantially parallel to the primary bore. One or more cam lock bores adapted to house one or more at least partially rotatable cam locks, are offset from the pin cam bores such that each cam pin bore partially intersects a corresponding cam lock bore to form an aperture through which the cam lock engages the cam pin. One or more cam pins are connected to the stripper rubber; and one or more at least partially rotatable cam locks housed in the cam lock bores of the adapter optionally engage or disengage the pin cams to respectively connect or disconnect the stripper rubber to or from the equipment.
    Type: Application
    Filed: February 11, 2004
    Publication date: August 11, 2005
    Inventors: John Williams, Charles Bishop
  • Publication number: 20050148558
    Abstract: The invention provides a stabilized 1?-hydroxyvitamin D (“SHVD”) which is particularly well suited for pharmaceutical formulations.
    Type: Application
    Filed: February 24, 2005
    Publication date: July 7, 2005
    Applicant: Bone Care International, Inc.
    Inventors: Joyce Knutson, Richard Mazess, Charles Bishop
  • Publication number: 20050133220
    Abstract: A rotating tool combinable with other downhole tools into a tool string, where the rotating tool is capable of imparting a rotational force onto the tool string. The tool string is suspendable from a threaded lead screw. Optionally, a gyroscope can be included to generate azimuthal readings and confirm the azimuthal orientation of the tool string. The rotating tool includes a compression assembly, a hydraulic assembly, and a stationary assembly. Actuation of a valve on the hydraulic assembly provides for the release of fluid therein that allows for movement of a rotating piston. Rotation of the piston is produced as it travels axially along the threaded lead screw, the rotation of the piston is subsequently transferred to the rotating tool.
    Type: Application
    Filed: December 17, 2003
    Publication date: June 23, 2005
    Inventor: Charles Bishop
  • Publication number: 20050082921
    Abstract: An electric machine having a stator, a rotor, a first intermediate portion, an end cap, a second intermediate portion, and a second end cap. The first and second intermediate portions partially cover the stator. The electric machine further includes a fastener that couples the first and second end caps.
    Type: Application
    Filed: October 16, 2003
    Publication date: April 21, 2005
    Applicant: A.O. Smith Corporation
    Inventors: Robert Schurter, Charles Bishop, Alan Lesak