Patents by Inventor Charles C. Stutz

Charles C. Stutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN BLOOD-BRAIN BARRIER TARGETING ANTIBODIES
    Publication number: 20230331835
    Abstract: The present invention provides antibodies or antigen-binding fragments thereof including single chain variable fragment (scFv) antibodies that specifically bind to and translocate the blood-brain barrier and methods of use.
    Type: Application
    Filed: January 28, 2021
    Publication date: October 19, 2023
    Inventors: Eric V. SHUSTA, Charles C. STUTZ, Loukas GOULATIS, Julia GEORGIEVA
  • BLOOD BRAIN BARRIER SELECTIVE ANTIBODIES AND METHODS OF USE
    Publication number: 20210277108
    Abstract: The present invention provides antibodies or antigen binding fragments thereof including single chain variable fragment (scFv) antibodies that specifically bind to the blood brain barrier in vivo and methods of use.
    Type: Application
    Filed: July 24, 2019
    Publication date: September 9, 2021
    Inventors: Eric V. SHUSTA, Charles C. STUTZ
  • Blood-brain barrier targeting antibodies
    Patent number: 9629801
    Abstract: This application discloses a BBB-selective antibody. The BBB-selective antibody comprises a protein encoded by a DNA sequence comprising SEQ ID NO:7 (CDRH1 of scFv 15), SEQ ID NO:8 (CDRH2 of scFv 15), SEQ ID NO:9 (CDRH3 of scFv 15), SEQ ID NO:10 (CDRL1 of scFv 15), SEQ ID NO:11 (CDRL2 of scFv 15) and SEQ ID NO:12 (CDRL3 of scFv 15) or a DNA sequence comprising SEQ ID NO:19 (CDRH1 of scFv 38), SEQ ID NO:20 (CDRH2 of scFv 38), SEQ ID NO:21 (CDRH3 of scFv 38), SEQ ID NO:22 (CDRL1 of scFv 38), SEQ ID NO:23 (CDRL2 of scFv 38) and SEQ ID NO:24 (CDRL3 of scFv 38). Preferably, the BBB-selective antibody comprises a protein encoded by SEQ ID NO:1 or 3.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: April 25, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Eric V. Shusta, Angela R Jones, Charles C. Stutz
  • Blood-Brain Barrier Targeting Antibodies
    Publication number: 20150196663
    Abstract: A BBB-selective antibody comprising a protein encoded by SEQ ID NO:1 or 3 or comprising a peptide encoded by CDR H1, CDR H2, CDR H3, CDRL1, CDRL2 or CDRL3 of SEQ ID NO:1 or CDR H1, CDR H2, CDR H3, CDRL1, CDRL2, or CDRL3 of SEQ ID NO: 3 is disclosed.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 16, 2015
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Eric V. Shusta, Angela R Jones, Charles C. Stutz