Abstract: In part, the disclosure relates to an imaging system that includes a control system; image sensors in electrical communication with the control system, the one or more image sensors support data collection relative to a first pixel subwindow; and an optical assembly, the optical assembly oriented to receive light from the target and direct the light to the image sensor; wherein the optical assembly has an imaging focal volume within the imaging environment that spans a range of focus. The timing system is in electrical communication with the one or more image sensors, an illumination system and a translation assembly. A translation assembly may move target in imaging environment. The timing systems triggers illumination system to illuminate the target and the one or more sensors to image the target when image sensor pixel values in the first pixel subwindow align with at least a portion of the target.

Abstract: The invention provides a new system and method for imaging a specimen. The system projects a three-dimensional crystalline pattern of light, a tessellation, and records the specimen's emitted light at locations where a portion of the specimen coincides with the pattern.

Abstract: Improved methods and systems for imaging are provided. Specifically, systems and methods for extending the range of a digital zoom are provided in which an imaging system provides continuous magnification over a plurality of interleaved optical pathways and digital zooming imagers. Systems and methods of centering an image as the field of view changes, and for masking out undesirable obstacles from a magnified image are also provided.

Abstract: The invention provides an improved robotic handler for multi-well plates. The handler comprises a vertical elevator with integral mounts for instruments used in cellular experiments. This solution reduces overall mechanical complexity while reducing the working volume of previous collections of devices with similar function.

Abstract: The invention provides an novel imaging system for microscopy including both continuous motion and stationary field image acquisition. More specifically, the invention provides a system that can translate a specimen relative to the field-of-view of an imager while synchronously acquiring image data. Using the same imaging optics and imager, the system can acquire stationary images at any location on the specimen.

Abstract: The invention is a system and method for controllable alignment of any of a plurality of electro-optical components mounted to a circuit board with an optical axis. In one embodiment, the invention provides an improved illumination system for microscopy. The system incorporates a circuit board 31 providing structure and directly mounting a plurality of light emitting sources. The mounted light sources are rotatably alignable with a plurality of optical axes. The system further includes selectable conditioning of the sources.

Abstract: Improved methods and systems for imaging are provided. Specifically, systems and methods for extending the range of a digital zoom are provided in which an imaging system provides continuous magnification over a plurality of interleaved optical pathways and digital zooming imagers. Systems and methods of centering an image as the field of view changes, and for masking out undesirable obstacles from a magnified image are also provided.

Abstract: A downhole tool includes a device to be activated by electrical energy and a micro-switch that includes conductors and an element between the first and second conductors selected from the group consisting of: a dielectric element capable of being modulated to provide a conductive path in response to receipt of electrical energy; and an element moveable in response to application of an electrical energy. The micro-switch may be formed of microelectromechanical system (MEMS) technology or microelectronics technology.

Abstract: A downhole tool includes a device to be activated by electrical energy and a micro-switch that includes conductors and an element between the first and second conductors selected from the group consisting of: a dielectric element capable of being modulated to provide a conductive path in response to receipt of electrical energy; and an element moveable in response to application of an electrical energy. The micro-switch may be formed of microelectromechanical system (MEMS) technology or microelectronics technology.

Abstract: A downhole tool includes a device to be activated by electrical energy and a micro-switch that includes conductors and an element between the first and second conductors selected from the group consisting of: a dielectric element capable of being modulated to provide a conductive path in response to receipt of electrical energy; and an element moveable in response to application of an electrical energy. The micro-switch may be formed of microelectromechanical system (MEMS) technology or microelectronics technology.