Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: A method, non-transitory computer readable medium and an application manager computing device that assists with provisioning applications based on user anticipated workloads includes obtaining, a user anticipated resource based on information within a user workload database, prior to receiving a request from a client computing device. The obtained user anticipated resource is provisioned. The provisioned user anticipated resource is provided upon establishing a session with the requesting client computing device.

Abstract: Methods, computer-readable media, and apparatuses for network flow state preservation include migration of at least one application hosted on a first server device to a second server device coupled to a second traffic management device is detected at a first traffic management device. At least a portion of connection state information associated with a network connection between at least one client device and the application is communicated by the first traffic management device to the second traffic management device via a communication channel between the first and second traffic management devices. The application is provided by the first traffic management device to the at least one client device during the migration based upon the connection state information.

Abstract: Each of a plurality of thread boundaries comprises functionality to be performed for a given event by a single thread. A plurality of queues through which events may be routed may be coupled to the thread boundaries. A plurality of tasks may be configured in a defined relationship, each task being associated with a thread boundary and comprising a unit of code for performing a specific function. Resources may be allocated to thread boundaries based on queue depth.

Abstract: A dynamic content routing network routes update messages containing updates to properties of live objects from input sources to clients. The clients receive a web page having live objects, identify the object IDs associated with the objects, and contact an object state storage to obtain update messages specifying the objects' initial properties. The clients register the object IDs with the routing network. The routing network maintains a registry of object IDs and clients. The input source provides an update message to the routing network containing the object ID and data for updating a property of the object. The routing network routes update messages from the input source to the clients registered for the object ID contained in the message. Upon receipt of the message, a client updates the specified property of the live object. The update messages are also provided to, and stored by, the object state storage.

Abstract: A dynamic content routing network routes update messages containing updates to properties of live objects from input sources to clients having the objects. Certain objects served to clients by a server are indicated as “live.” When the clients receive live objects, the clients identify the object IDs associated with the objects and register the object IDs with the routing network. The routing network maintains a registry of object IDs and clients. An input source provides an update message to the routing network containing the object ID and data specifying an update to a property of the object. The routing network routes the message to each client that has registered for the object ID contained in the message. Upon receipt of the message, a client updates the specified property of the live object.

Abstract: Each of a plurality of thread boundaries comprises functionality to be performed for a given event by a single thread. A plurality of queues through which events may be routed may be coupled to the thread boundaries. A plurality of tasks may be configured in a defined relationship, each task being associated with a thread boundary and comprising a unit of code for performing a specific function. Resources may be allocated to thread boundaries based on queue depth.

Abstract: A dynamic content routing network routes update messages containing updates to properties of live objects from input sources to clients having the objects. Certain objects served to clients by a server are indicated as “live.” When the clients receive live objects, the clients identify the object IDs associated with the objects and register the object IDs with the routing network. The routing network maintains a registry of object IDs and clients. An input source provides an update message to the routing network containing the object ID and data specifying an update to a property of the object. The routing network routes the message to each client that has registered for the object ID contained in the message. Upon receipt of the message, a client updates the specified property of the live object.

Abstract: A dynamic content routing network routes update messages containing updates to properties of live objects from input sources to clients. The clients receive a web page having live objects, identify the object IDs associated with the objects, and contact an object state storage to obtain update messages specifying the objects'initial properties. The clients register the object IDs with the routing network. The routing network maintains a registry of object IDs and clients. The input source provides an update message to the routing network containing the object ID and data for updating a property of the object. The routing network routes update messages from the input source to the clients registered for the object ID contained in the message. Upon receipt of the message, a client updates the specified property of the live object. The update messages are also provided to, and stored by, the object state storage.