Abstract: The present disclosure relates to chemical compounds that modulate JAK-2 signaling, which are useful in the treatment of disorders associated with JAK-2 signaling dysfunction such as, for example, disorders of cellular proliferation (e.g., cancer) and autoimmune and inflammatory disorders, pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A system for poisoned data management includes an interface and a processor. The interface is configured to receive an indication of poisoned data in a published event. The processor is configured to mark the poisoned data in a data graph; mark in the data graph a set of downstream nodes as poisoned; and store the data graph.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A system for poisoned data management includes an interface and a processor. The interface is configured to receive an indication of poisoned data in a published event. The processor is configured to mark the poisoned data in a data graph; mark in the data graph a set of downstream nodes as poisoned; and store the data graph.

Abstract: A system for poisoned data management includes an interface and a processor. The interface is configured to receive an indication for remediation of poisoned data. The processor is configured to correct the poisoned data associated with an event in a storage location, wherein the storage location is determined based at least in part on a data graph associated with the poisoned data, and wherein the data graph is determined based at least in part on the data sourcing information of a published event associated with the poisoned data.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A jig for finishing a workpiece with a handheld router or other handheld motor-driven rotational tool assembly is provided. The jig includes a baseplate that is precisely aligned and attached to a router. Guides, including a main guide and a support guide, are provided. The main guide is configured to precisely align with and fasten to the base plate in several different jig configurations. Right-angle adaptors attach to the guides and precisely align with and attach to the guides and the base plate to form several different jig configurations. Side plates secure the workpiece therebetween and provide a surface along which the main guide may slide to facilitate finishing operations on the workpiece.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: An electric vehicle system for transporting human passengers or cargo includes an electric vehicle that includes a body, a plurality of wheels, a cargo area, an electric motor for propelling the electric vehicle, and a primary battery for providing electrical power to the electric motor for propelling the electric vehicle. An auxiliary battery module is attachable to the electric vehicle for providing electrical power to the electric motor via a first electrical connector at the auxiliary battery module and a second electrical connector at the electric vehicle that mates with the first electrical connector. The auxiliary battery module can be positioned in the cargo area while supplying power to the electric motor, and can be removable and reattachable from the electric vehicle. The auxiliary battery module includes an integrated cooling system for cooling itself during operation of the electric vehicle including a conduit therein for circulating coolant.

Abstract: Methods for the ex vivo modification of the surfaces of viable tissue result in tissue modifications that are stable and/or result in the controlled release of active compounds, and are expected to provide effective protection for transplanted tissue subsequent to transplant.

Abstract: A mobile charge/discharge device for being electrically connected to a power source and a first power receiving device is disclosed. The mobile charge/discharge device includes a detection circuit detecting a first working power of the power source and a second working power of the first power receiving device; an input port having a first power supply pin for being electrically connected to the power source; a first output port having a second power supply pin for being electrically connected to the first power receiving device; and a controlling circuit controlling the power source to supply the first power receiving device with a power according to one of the first working power and the second working power and supply the mobile charge/discharge device with a power according to the difference of the first working power and the second working power at the same time.

Abstract: In an aspect of the disclosure, a method, a computer-readable medium, and an apparatus are provided. The apparatus may receive an otw signal that is associated with low-path pass information and transmission data. The apparatus may apply a cost function and an update function to the otw signal prior to sending the otw signal to an oscillator. The apparatus may determine a correction factor for use in estimating a gain of the oscillator based at least in part on an output of the update function.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: In an aspect of the disclosure, a method, a computer-readable medium, and an apparatus are provided. The apparatus may receive an otw signal that is associated with low-path pass information and transmission data. The apparatus may apply a cost function and an update function to the otw signal prior to sending the otw signal to an oscillator. The apparatus may determine a correction factor for use in estimating a gain of the oscillator based at least in part on an output of the update function.

Abstract: A database system is disclosed for accessing databases, updating hands information associated with users. The database system can include a server. The server can retrieve and store data in the database. The server can retrieve a first request from a first computer over a network, the first request including a first set of authentication data. The server can identify the user and retrieve a first set of hands information data associated with the user from the database. The server can generate a first set of game data and transmit the game data to the first computer. It can then receive a first set of hands data from the first computer. It can compute a first game result based on the first set of hands data, the first set of game data and a first set of game rules.

Abstract: A jig for finishing a workpiece with a handheld router or other handheld motor-driven rotational tool assembly is provided. The jig includes a baseplate that is precisely aligned and attached to a router. Guides, including a main guide and a support guide, are provided. The main guide is configured to precisely align with and fasten to the base plate in several different jig configurations. Right-angle adaptors attach to the guides and precisely align with and attach to the guides and the base plate to form several different jig configurations. Side plates secure the workpiece therebetween and provide a surface along which the main guide may slide to facilitate finishing operations on the workpiece.

Abstract: A firearm and a kit for modifying a firearm is provided. The firearm has an upper receiver, a lower receiver, and a releasable magazine that releases when the upper receiver rotates away from the lower receiver. The firearm further has a firing pin with a striking end that has a cylindrical shape and a substantially sharp shoulder. A hammer is also provided with a depression disposed in a front surface thereof, the front surface configured to strike the striking end of the firing pin when the upper receiver is next to the lower receiver, and the depression configured to align with the striking end of the firing pin when the upper receiver rotates away from the lower receiver.