Patents by Inventor Charles Chen

Charles Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210147418
    Abstract: Provided are a class of KRAS G12C mutein inhibitors, which relate in particular to a compound represented by formula (I), an isomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 27, 2021
    Publication date: May 20, 2021
    Inventors: Yaxian CAI, Zhaobing XU, Hailong YANG, Shiqi HAN, Guoping HU, Lihong HU, Charles Z. DING, Jian LI, Shuhui CHEN
  • Patent number: 11008331
    Abstract: 10-oxo-6,1-dihydrobenzo[e]pyrido[1,2-c][1,3]oxazine-9-carboxylic acid derivatives of formula (I) as hepatitis B surface antigen inhibitors or pharmaceutically acceptable salts thereof, and uses of a compound of formula (I) or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof in preparation of medicaments for treatment of viral hepatitis B.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: May 18, 2021
    Assignee: FUJIAN COSUNTER PHARMACEUTICAL CO., LTD.
    Inventors: Fei Sun, Jinhua Du, Yanbin Hu, Lili Zhou, Charles Z. Ding, Shuhhui Chen
  • Publication number: 20210132272
    Abstract: An optical device includes: (1) a substrate; and (2) multiple meta-lenses disposed on the substrate, each meta-lens of the meta-lenses including multiple nanofins disposed on a respective region of the substrate, the nanofins together specifying a phase profile of the meta-lens.
    Type: Application
    Filed: December 19, 2017
    Publication date: May 6, 2021
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Alexander Yutong ZHU, Wei Ting CHEN, Mohammadreza KHORASANINEJAD, Jaewon OH, Aun ZAIDI, Robert Charles DEVLIN, Federico CAPASSO
  • Publication number: 20210122608
    Abstract: This disclosure relates to a system and method for monitoring a sheave bearing condition, and in particular relates to passenger conveyer systems, such as elevator systems, employing the system and method. An example passenger conveyer system includes a suspension member, and a sheave configured to rotate on a bearing. The suspension member is wrapped around at least a portion of the sheave. Further, the system includes a sensor mounted adjacent an end of the suspension member, and a controller configured to determine a condition of the bearing based on an output of the sensor.
    Type: Application
    Filed: October 28, 2019
    Publication date: April 29, 2021
    Inventors: Yan Chen, David R. Polak, Paul R. Braunwart, Zaffir A. Chaudhry, Charles C. Coffin
  • Publication number: 20210125222
    Abstract: In general, in one aspect, a method includes compiling user interaction statistics for a set of content items displayed in association with a first target media document having a non-textual portion, at least some of the content items associated with one or more keywords, based on the interaction statistics, associating the first target media document with at least some of the keywords associated with the content items, and based on a common attribute of the first target media document and a second target media document having a non-textual portion, associating the second target media document with at least some of the keywords assigned to the first target media document. Other aspects include corresponding systems, apparatus, and computer programs stored on computer storage devices.
    Type: Application
    Filed: January 4, 2021
    Publication date: April 29, 2021
    Applicant: Google LLC
    Inventors: Kai Chen, Steven G. Dropsho, Charles Johan Larsson TIBELL, Diego Federici
  • Patent number: 10988348
    Abstract: Disclosed is an escalator system that has: an escalator step; and load sensors secured to the escalator step, wherein the load sensors are configured to: sense an escalator loading; and transfer, to an escalator controller, sensor data indicative of the escalator loading.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: April 27, 2021
    Assignee: OTIS ELEVATOR COMPANY
    Inventors: Walter Thomas Schmidt, Charles C. Coffin, Shihemn Chen, Enrico Manes, Paul R. Braunwart, Anais Espinal, Kishore K. Reddy, Soumalya Sarkar
  • Publication number: 20210115035
    Abstract: Disclosed are a class of new monocyclic ?-lactam compounds, an isomer thereof or pharmaceutically acceptable salts thereof, and a pharmaceutical composition comprising the compounds, and the use of same in preparing drugs for treating diseases associated with bacterial infection. Specifically disclosed are the compounds as shown in formula (I?) and formula (II?), isomers thereof or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: January 29, 2019
    Publication date: April 22, 2021
    Inventors: Lianghu GU, Wei LUO, Zhigang HUANG, Charles Z. DING, Cheng LI, Shuhui CHEN
  • Publication number: 20210106285
    Abstract: A method for clip selection includes receiving through an interface to a medical imaging device, a selection of a diagnostic procedure and a target portion of a mammalian body. Thereafter, the device acquires video clip imagery of the target portion and stores the video clip imagery in an image store. Each video clip of the video clip imagery is then image processed to determine a view and a quality of each video clip and a rule is retrieved from a rules base corresponding to the selected diagnostic procedure and target portion. In this regard, the rule specifies a requisite view and quality of the video clip imagery. Finally, the retrieved rule is applied to the video clip imagery as a filter to produce a subset of video clip imagery satisfying the specified requisite view and quality and the subset of video clip imagery is stored in the image store.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 15, 2021
    Inventors: Charles Cadieu, Ha Hong, Kilian Koepsell, Johan Mathe, Nicolas Poilvert, Michael Cannon, Nathanael Romano, Natalia Bilenko, Charles Chen, Nina Miolane
  • Publication number: 20210106284
    Abstract: A method for clip selection includes receiving through an interface to a medical imaging device, a selection of a diagnostic procedure and a target portion of a mammalian body. Thereafter, the device acquires video clip imagery of the target portion and stores the video clip imagery in an image store. Each video clip of the video clip imagery is then image processed to determine a view and a quality of each video clip and a rule is retrieved from a rules base corresponding to the selected diagnostic procedure and target portion. In this regard, the rule specifies a requisite view and quality of the video clip imagery. Finally, the retrieved rule is applied to the video clip imagery as a filter to produce a subset of video clip imagery satisfying the specified requisite view and quality and the subset of video clip imagery is stored in the image store.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 15, 2021
    Inventors: Charles Cadieu, Ha Hong, Kilian Koepsell, Johan Mathe, Nicolas Poilvert, Michael Cannon, Nathanael Romano, Natalia Bilenko, Charles Chen, Nina Miolane
  • Publication number: 20200245976
    Abstract: In a method, system and computer program product for retrospective image clip saving for ultrasound imagery, the method includes first repeatedly acquiring different ultrasound image clips of a single view of a target feature through an ultrasound imaging probe of an ultrasound imaging system. Thereafter, each of the acquired different ultrasound image clips may be stored in a buffer of the ultrasound imaging system and a value assigned to each of the image clips according to a measured characteristic. A save-best-clip mode of the ultrasound imaging system is then activated and, in response to the activation, each of the acquired different ultrasound image clips are compared in the buffer based upon respective measured characteristics, at least one of the clips demonstrating an optimal value for the measured characteristic is identified and the identified clip or clips saved in memory of the ultrasound imaging system in correspondence with the single view.
    Type: Application
    Filed: January 31, 2019
    Publication date: August 6, 2020
    Inventors: Charles Cadieu, Charles Chen, Ha Hong, Ching Hsieh, Kilian Koepsell
  • Patent number: 10631791
    Abstract: A method for clip selection includes receiving through an interface to a medical imaging device, a selection of a diagnostic procedure and a target portion of a mammalian body. Thereafter, the device acquires video clip imagery of the target portion and stores the video clip imagery in an image store. Each video clip of the video clip imagery is then image processed to determine a view and a quality of each video clip and a rule is retrieved from a rules base corresponding to the selected diagnostic procedure and target portion. In this regard, the rule specifies a requisite view and quality of the video clip imagery. Finally, the retrieved rule is applied to the video clip imagery as a filter to produce a subset of video clip imagery satisfying the specified requisite view and quality and the subset of video clip imagery is stored in the image store.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: April 28, 2020
    Assignee: Caption Health, Inc.
    Inventors: Charles Cadieu, Ha Hong, Kilian Koepsell, Johan Mathe, Nicolas Poilvert, Michael Cannon, Nathanael Romano, Natalia Bilenko, Charles Chen, Nina Miolane
  • Patent number: 10623105
    Abstract: In an asynchronous optical modulation system, a drive circuit may generate a plurality of dither tones in accordance with a predetermined dither frequency ratio. Based on the components of the dither frequency ratio, the optical modulation system may be configured to determine a feedback signal magnitude component that is independent of the delay ? and a feedback signal sign component that is also independent of the delay ?. A feedback signal that is independent of the delay ? can then be reconstructed based on the feedback signal magnitude component and the feedback signal sign component.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: April 14, 2020
    Assignee: Infinera Corporation
    Inventors: Rene Marcel Schmogrow, Arseny Vasilyev, Charles Chen
  • Patent number: 10571714
    Abstract: An embodiment includes a snap-fit temple interface of a lens. The snap-fit temple interface includes a first snap-fit feature and a second snap-fit feature. The first snap-fit feature of the lens is configured to be engaged with a first corresponding snap-fit feature of a temple assembly. The first snap-fit feature is configured to be engaged with the first corresponding snap-fit feature by a first movement of the lens in a first direction relative to the temple assembly followed by a second movement of the lens in a second direction relative to the temple assembly. The second snap-fit feature of the lens is configured to be engaged with a second corresponding snap-fit feature of the temple assembly. The second snap-fit feature is configured to be engaged with the second snap-fit feature by the second movement of the lens in the second direction relative to the temple assembly. The first direction is substantially perpendicular to the second direction.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: February 25, 2020
    Assignee: Advanced Eye Protection IP Holding
    Inventors: Stephen Charles Chen, Chen Chang Wang Lee, Zong-Lin Du
  • Patent number: 10559024
    Abstract: Methods are described herein related to enabling users to purchase a product or service by providing a voice request and/or an image. An example method may involve: (a) receiving, by a hybrid response system (“HRS”), a first speech-segment message that comprises a speech segment and is associated with a user-account, (b) the HRS determining that the speech segment indicates a purchase request, (c) the HRS determining a target product/service based on at least the purchase request, (d) the HRS determining a confidence level associated with a purchase of the target product/service, (e) if the confidence level is greater than or equal to a threshold level, then the HRS sending a purchase order, via the associated user-account, for the target product or service, otherwise, the HRS sending the purchase request and the target product/service to at least one guide computing system to facilitate a response to the purchase request.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: February 11, 2020
    Assignee: X Development LLC
    Inventors: Charles Chen, Rakesh Yadav
  • Publication number: 20190392581
    Abstract: A method for clip selection includes receiving through an interface to a medical imaging device, a selection of a diagnostic procedure and a target portion of a mammalian body. Thereafter, the device acquires video clip imagery of the target portion and stores the video clip imagery in an image store. Each video clip of the video clip imagery is then image processed to determine a view and a quality of each video clip and a rule is retrieved from a rules base corresponding to the selected diagnostic procedure and target portion. In this regard, the rule specifies a requisite view and quality of the video clip imagery. Finally, the retrieved rule is applied to the video clip imagery as a filter to produce a subset of video clip imagery satisfying the specified requisite view and quality and the subset of video clip imagery is stored in the image store.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 26, 2019
    Inventors: Charles Cadieu, Ha Hong, Kilian Koepsell, Johan Mathe, Nicolas Poilvert, Michael Cannon, Nathanael Romano, Natalia Bilenko, Charles Chen, Nina Miolane
  • Patent number: 10185158
    Abstract: An aspect includes a temple assembly that is configured to retain one or more lenses relative to a head of a user. The temple assembly may include a temple substrate and an insert. The temple substrate may be comprised of one or more polymers. The insert may be located at least partially within the temple substrate. The insert is configured to impose a spring force against the head of the user and is configured to allow at least a portion of the temple substrate to rotate axially about at least a portion of the insert such that the portion of the temple substrate deforms relative to the insert and at least partially independently of the insert.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: January 22, 2019
    Assignee: ADVANCED EYE PROTECTION IP HOLDING
    Inventor: Stephen Charles Chen
  • Patent number: 10110370
    Abstract: Systems and methods providing wireless synchronization of wave arrays may include an antenna that receives a wireless injection signal and another antenna that radiates a locked wave signal corresponding to the injection signal. In some embodiments, these systems may also provide a low noise amplifier, voltage controlled oscillator (VCO), buffer amplifier(s), phase shifter, and/or multi-stage amplifier. In some embodiments, the injection signal may be provided on an even harmonic, and the intended transmission frequency signal is on an odd harmonic of the locked signal. The substrate thickness may be designed to radiate electromagnetic waves in odd harmonics of the locked signal. In yet another embodiment, polarization of a receiving antenna may be orthogonal to a transmitter antenna.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: October 23, 2018
    Assignee: William Marsh Rice University
    Inventors: Charles Chen, Aydin Babakhani
  • Patent number: 10057387
    Abstract: Communication traffic processing architectures and methods are disclosed. Processing load on main Central Processing Units (CPUs) can be alleviated by offloading data processing tasks to separate hardware. In one implementation, a processing architecture includes a main processor configured to execute a first portion of a driver software to perform protocol control and management task associated with control or management packets in a packet-based protocol according to which packets are received from a device, an offload processor configured to execute a second portion of the driver software to perform data processing task for data packets received according to the packet-based protocol, an interface to enable communication with the device, and an interconnect coupled to the main processor, to the offload subsystem, and to the interface.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: August 21, 2018
    Assignee: REALTEK SINGAPORE PTE LTD
    Inventors: Charles Chen, Ryan Patrick Donohue, Donggun Keung, Xi Chen, Xiaochong Cao, Zeineddine Chair
  • Publication number: 20180231797
    Abstract: An embodiment includes a snap-fit temple interface of a lens. The snap-fit temple interface includes a first snap-fit feature and a second snap-fit feature. The first snap-fit feature of the lens is configured to be engaged with a first corresponding snap-fit feature of a temple assembly. The first snap-fit feature is configured to be engaged with the first corresponding snap-fit feature by a first movement of the lens in a first direction relative to the temple assembly followed by a second movement of the lens in a second direction relative to the temple assembly. The second snap-fit feature of the lens is configured to be engaged with a second corresponding snap-fit feature of the temple assembly. The second snap-fit feature is configured to be engaged with the second snap-fit feature by the second movement of the lens in the second direction relative to the temple assembly. The first direction is substantially perpendicular to the second direction.
    Type: Application
    Filed: February 13, 2018
    Publication date: August 16, 2018
    Inventors: Stephen Charles Chen, Chen Chang Wang Lee, Zong-Lin Du
  • Patent number: 10010891
    Abstract: A high capacity magnetic filter for separating magnetic and non-magnetic contaminants from contaminated liquid streams includes a housing having (i) an interior region between the inlet and outlet for a process stream, (ii) a plurality of vertically oriented, elongated non-magnetic holder sleeves positioned within the interior region (iii) paramagnetic metal packing material that is randomly distributed in the interior region to form a packed compartment that has a void volume which is above 95 percent, and (iv) a device to generate a magnetic field within the interior region. Generation of a uniform magnetic field within the packed compartment magnetizes the holder sleeves and matrix of packing materials. The holder sleeves and matrix create a large surface area for collecting the contaminants.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: July 3, 2018
    Assignee: ALLNEW Chemical Technology Company
    Inventors: Kosky Yen, Peter Wu, Michael Lee, Charles Chen