Patents by Inventor Charles Cobbs

Charles Cobbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11499972
    Abstract: A method of characterizing a glioblastoma multiforme (GBM) stem cell (GSC), comprising culturing the GSC to provide a culture, contacting a first set of aliquots of the culture with individual compounds selected from a panel of compounds, identifying two or more of the selected compounds that cause more than a threshold level of cell death in the first set of aliquots, and characterizing the GSC as suitable for treatment with one or more combinations comprising the two or more identified compounds. A panel of chemical compounds, the compounds selected by a method comprising surgically resecting the tumor, culturing a GSC derived from GBM tissue derived from a GBM tumor, contacting aliquots thereof with individual compounds selected from a panel of compounds, and identifying two or more of the selected compounds that cause more than a threshold level of cell death in the aliquots, thereby identifying the compounds.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: November 15, 2022
    Assignee: Swedish Health Services
    Inventors: Parvinder Hothi, Charles Cobbs
  • Publication number: 20210389299
    Abstract: A method of characterizing a glioblastoma multiforme (GBM) stem cell (GSC), comprising culturing the GSC to provide a culture, contacting a first set of aliquots of the culture with individual compounds selected from a panel of compounds, identifying two or more of the selected compounds that cause more than a threshold level of cell death in the first set of aliquots, and characterizing the GSC as suitable for treatment with one or more combinations comprising the two or more identified compounds. A panel of anti-GBM chemotherapeutic compounds, the compounds selected by a method comprising surgically resecting the tumor, culturing a GSC derived from GBM tissue derived from a GBM tumor, contacting aliquots thereof with individual compounds selected from a panel of compounds, and identifying two or more of the selected compounds that cause more than a threshold level of cell death in the aliquots, thereby identifying the compounds.
    Type: Application
    Filed: January 20, 2021
    Publication date: December 16, 2021
    Inventors: Parvinder HOTHI, Charles COBBS
  • Publication number: 20180252717
    Abstract: A method of characterizing a glioblastoma multiforme (GBM) stem cell (GSC), comprising culturing the GSC to provide a culture, contacting a first set of aliquots of the culture with individual compounds selected from a panel of compounds, identifying two or more of the selected compounds that cause more than a threshold level of cell death in the first set of aliquots, and characterizing the GSC as suitable for treatment with one or more combinations comprising the two or more identified compounds. A panel of chemical compounds, the compounds selected by a method comprising surgically resecting the tumor, culturing a GSC derived from GBM tissue derived from a GBM tumor, contacting aliquots thereof with individual compounds selected from a panel of compounds, and identifying two or more of the selected compounds that cause more than a threshold level of cell death in the aliquots, thereby identifying the compounds.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 6, 2018
    Applicant: Swedish Health Services
    Inventors: Parvinder HOTHI, Charles COBBS
  • Publication number: 20180209959
    Abstract: A method of characterizing a glioblastoma multiforme (GBM) stem cell (GSC), comprising culturing the GSC to provide a culture, contacting a first set of aliquots of the culture with individual compounds selected from a panel of compounds, identifying two or more of the selected compounds that cause more than a threshold level of cell death in the first set of aliquots, and characterizing the GSC as suitable for treatment with one or more combinations comprising the two or more identified compounds. A panel of anti-GBM chemotherapeutic compounds, the compounds selected by a method comprising surgically resecting the tumor, culturing a GSC derived from GBM tissue derived from a GBM tumor, contacting aliquots thereof with individual compounds selected from a panel of compounds, and identifying two or more of the selected compounds that cause more than a threshold level of cell death in the aliquots, thereby identifying the compounds.
    Type: Application
    Filed: July 31, 2015
    Publication date: July 26, 2018
    Inventors: Parvinder HOTHI, Charles COBB
  • Patent number: 9340788
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: May 17, 2016
    Assignee: Sutter West Bay Hospitals
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Publication number: 20150011478
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
    Type: Application
    Filed: May 5, 2014
    Publication date: January 8, 2015
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Publication number: 20140161811
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
    Type: Application
    Filed: May 3, 2013
    Publication date: June 12, 2014
    Applicant: Sutter West Bay Hospitals
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Patent number: 8716257
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
    Type: Grant
    Filed: April 15, 2012
    Date of Patent: May 6, 2014
    Assignee: Sutter West Bay Hospitals
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Patent number: 8435510
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: May 7, 2013
    Assignee: Sutter West Bay Hospitals
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Publication number: 20120264675
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
    Type: Application
    Filed: April 15, 2012
    Publication date: October 18, 2012
    Applicant: SUTTER WEST BAY HOSPITALS
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Publication number: 20110311523
    Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
    Type: Application
    Filed: August 7, 2008
    Publication date: December 22, 2011
    Applicant: CALIFORNIA PACIFIC MEDICAL CENTER
    Inventors: Charles Cobbs, Liliana Soroceanu
  • Publication number: 20050163823
    Abstract: Exogenous enzyme treatment techniques for ruminant feed are provided that are specially adapted for increasing availability of dietary phosphorus and decreasing phosphorus excretion in ruminants. Preferred embodiments of the present invention include compositions comprising an exogenous phytase enzyme and an exogenous cellulase formulation.
    Type: Application
    Filed: January 28, 2004
    Publication date: July 28, 2005
    Inventor: Charles Cobb
  • Publication number: 20040191378
    Abstract: An improved system and method for producing tortillas from a plurality of dough balls in a substantially continuously moving head press includes collating the dough balls in a feed section in which the product is deposited on a moving conveyor band. The product is then transferred to a reciprocating pressing apparatus where it is pressed to a desired diameter and thickness. The tortilla press operates in conjunction with the conveyor band in a closely controlled fashion to enable improved processing of the food product and resultant tortillas.
    Type: Application
    Filed: March 25, 2003
    Publication date: September 30, 2004
    Inventors: Adrian Barry Golby, William Charles Cobb