Abstract: A method of producing an offset lithographic printing plate including the steps of providing a grained, anodized and passivated aluminum plate of preferred surface roughness; applying a receptive coating to the grained aluminum plate; image-wise applying an inkjet fluid on top of the receptive coating; and heating the oleophilic inkjet fluid allowing an oleophilic resin of the inkjet fluid to bond with the grained aluminum.

Abstract: The present invention relates to methods of metallizing nucleic acid molecules and to methods of attaching nucleic acid molecules to conductive surfaces. Methods of detecting target nucleic acid molecules based on these techniques are also disclosed.

Abstract: A method and apparatus of producing images on a series of master plates that are suitable for use as printing plates for the reproduction of multiple copies of composite images from said plates. The master plates are supported with a predetermined alignment relative to each other before mounting on a printing press. Counterpart raster lines of images on the master plates are recorded simultaneously or substantially simultaneously using preferably an ink jet printer so that the counterpart raster lines are printed in alignment.

Abstract: The present invention relates to methods of metallizing nucleic acid molecules and to methods of attaching nucleic acid molecules to conductive surfaces. Methods of detecting target nucleic acid molecules based on these techniques are also disclosed.

Abstract: A method and apparatus of producing images on a series of master plates that are suitable for use as printing plates for the reproduction of multiple copies of composite images from said plates. The master plates are supported with a predetermined alignment relative to each other before mounting on a printing press. Counterpart raster lines of images on the master plates are recorded simultaneously or substantially simultaneously using preferably an ink jet printer so that the counterpart raster lines are printed in alignment.

Abstract: An apparatus for offset lithographic printing including an offset lithographic printing press including a printing cylinder having a surface including a mixture of cationic colloidal silica, fumed alumina, and a polymeric amine; and an inkjet printhead disposed to print a digital image on the printing cylinder with an ink jet fluid including a pigment and a polymeric dispersing agent, which ink jet fluid dries to produce a surface active to oleophilic lithographic printing inks.

Abstract: A method for preparing lithographic printing plates comprising coating a substrate with a mixture including colloidal silica, fumed alumina, polyethylenimine, a quaternary ammonium polymer and a hardener; utilizing an inkjet printer with pigmented inks to print a digital image on the coated substrate; and drying the image.

Abstract: An apparatus for offset lithographic printing including an offset lithographic printing press including a printing cylinder having a surface including a mixture of cationic colloidal silica, fumed alumina, and a polymeric amine; and an inkjet printhead disposed to print a digital image on the printing cylinder with a fluid that dries to produce a surface attractive to oleophilic lithographic printing inks.

Abstract: A method for preparing lithographic printing plates comprising coating a substrate with a mixture including colloidal silica, fumed alumina, polyethylenimine, a quaternary ammonium polymer and a hardener; utilizing an inkjet printer with pigmented inks to print a digital image on the coated substrate; and drying the image.

Abstract: An ink jet printing apparatus having a cleaning station that cleans the orifice plate with a cleaning liquid. The cleaning liquid includes a hydrophobic additive that has a strong affinity for the orifice plate material and which coats the orifice plate to form a protective coating. If a portion of the protective coating is removed, that portion will be repaired by the additive.

Abstract: A method for preparing lithographic plates including preparing a lithographic printing plate by coating a substrate with a mixture including silica, alumina and a polymeric amine; overcoating the coating with a protective layer; using an inkjet printer with pigmented inks to print a digital image on the coated substrate; and drying the inkjet image.

Abstract: A digital printing method for printing photographic quality images employs a printhead having a plurality of recording elements at least some of which recording elements are arranged in a line. A recording sheet is moved relative to the printhead to form an image on the recording sheet. The recording sheet has parallel spaced side edges. A page of image data to be printed on the recording sheet is provided that represents an image having top, bottom and side edges to establish a substantially rectangular image. The image is formed on the recording sheet through lines or bands of recording sequences that form the image so that the top side edge of the image is formed at an oblique angle to the side edges of the recording sheet wherein the oblique angle is between 15 degrees and 75 degrees. Alternatively, the top side edge of the image is formed perpendicular to the side edges of the recording sheet through formation of the image by swaths of recording sequences that are oblique to the top edge of the image.

Abstract: The present invention relates to a method of attaching nucleic acid molecules to two different electrical conductors, where a first set of oligonucleotide probes is attached to the first electrical conductors with an attachment chemistry which binds the first set of oligonucleotide probes to the first electrical conductors but not to the second electrical conductors. Then, a second set of oligonucleotide probes is attached to the second electrical conductors. The present invention also provides methods for attaching nucleic acid molecules to electrical conductors using a masking agent and methods for attaching nucleic acid molecules to electrical conductors by electrostatic attraction so that the oligonucleotide probes are chemically bound to the electrical conductors. The present invention also discloses methods and devices for detecting a target nucleic acid molecule in a sample.

Abstract: A method for microfluidic printing comprising pumping and mixing colored inks which comprise a mixture of colorants, fluids, and gel-forming or gel-initiating ingredients to form ink pixels and to transfer such ink pixels to a receiver transferring position; and transferring the ink pixels to a reflective receiver which contains gel-forming or gel-initiating ingredients so that the ingredients in the transferred ink pixels and in the receiver react to form a gel and the viscosity of the transferred ink rapidly increases to limit the flow of ink pixels whereby such ink pixels are fixed to the receiver and overprinting of colors is minimized.

Abstract: A method for preparing a lithographic plate which can react with an imaging fluid to form an image, including providing a hydrophilic support; forming a fluid-receiving layer that includes a water-soluble material which is chemically reactive with the imaging fluid; imagewise applying the imaging fluid to the fluid-receiving layer; and drying or curing the applied fluid to form an image in the fluid-receiving layer.

Abstract: A method of forming color proof images of inks on a printing stock prior to a production or press run, comprising the steps of providing a receiver having a peelable substrate, such receiver including a layer having a mordant in a binder formed over the substrate which will form a bond with colorant in the ink and an ink-receiving layer formed over the mordant layer which is permeable to ink, but which restricts spreading of ink as it passes through such layer to the mordant layer; depositing ink having colorants onto the ink-receiving layer to form a color proof image in the mordant layer; and laminating the receiver to a printing stock and removing the peelable substrate from the receiver to form the color proof.

Abstract: A method for preparing a lithographic plate which can react with an imaging fluid to form an image, including providing a hydrophilic support; forming a fluid-receiving layer that includes a water-soluble material which is chemically reactive with the imaging fluid; imagewise applying the imaging fluid to the fluid-receiving layer; and drying or curing the applied fluid to form an image in the fluid-receiving layer.

Abstract: An ink jet print head is provided that includes a nozzle plate having an outer metal layer having nozzles for ejecting ink drops, and a coating of a non-wetting polymer chemically bound over the outer surface of the metal layer of the plate. Preferably, the polymer is a block polymer having a head that includes the chemical group that chemically bonds with the outer metal layer, and a tail that is hydrophobic. The resulting polymer coating prevents inks from pooling, drying, and creating deposits which would otherwise impede or clog the ink jet nozzles. The chemical bonding between the non-wettable polymer and the metal surface creates a highly durable polymeric layer that resists being wiped off during both printing and head cleaning operations.

Abstract: A cleaning fluid for use with an inkjet printer having orifices for ejecting ink, the surface of the orifices at the ejection point being formed by a predetermined material includes a liquid for cleaning the orifice surface; and an additive in the liquid having a strong affinity for the material which forms the orifice surface and coats such surface to form a protective coating of such additive so that if a portion of the protective coating is removed, such portion will be repaired by the additive material.

Abstract: A lithographic imaging member is prepared by applying an ink jetable fluid to a fluid-receiving element that includes a clay-containing fluid-receiving surface layer. This layer also includes a water-soluble binder and a silane hardening agent. The applied fluid is an aqueous solution of a silane having multiple hydroxy, alkoxy or acetoxy groups that is readily absorbed in the clay-containing surface, and dried to provide an oleophilic image.