Abstract: A compact rope stretcher maintains the tension in an endless rope used for threading a web in a papermaking machine and includes a beam having a flange forming a track which is engaged by guide wheels supporting a pair of separate carriages. The carriages support corresponding rope sheaves for free rotation, and a pair of fluid cylinders are mounted on the beam and enclose pistons connected by corresponding piston rods directly to the corresponding carriages. The beam may be mounted on the papermaking machine with its track-forming flange extending at an angle to the horizontal so that the respective piston rods extend upwardly and downwardly from the cylinders. Pressurized fluid is supplied to the upper end of the one cylinder having the downwardly extending piston rod, and the upper end of the other cylinder is vented to atmosphere. The lower ends of the two cylinders are interconnected by a fluid passage to form a closed circuit which is filled with hydraulic fluid.

Abstract: An endorphin peptide is described that has a molecular weight by amino acid analysis of about 14,000 daltons, an infrared spectrum substantially as shown in FIG. 5, and an amino acid analysis substantially as follows:______________________________________ Amino Acid Nanomoles ______________________________________ Aspartic acid 9.4 Threonine 6.2 Serine 10.1 Glutamic acid 16.0 Proline 6.3 Glycine 18.6 Alanine 12.5 Valine 6.0 Methionine 1.0 Isoleucine 2.6 Leucine 7.1 Tyrosine 1.1 Phenylalanine 4.3 Histidine 3.6 Lysine 7.8 Arginine 2.8 Total 115.4 ______________________________________The peptide is immunoreactive against .beta.-endorfin rabbit antisera and displaces Naloxone from opiate receptors in brain tissue.

Abstract: A peptide endorphin having a molecular weight in the range of about 4500 to 5000 daltons is described. This peptide endorphin has .beta.-endorphin-like activity, reacting immunologically to rabbit antisera prepared against .beta.-endorphin and displacing Naloxone from opiate receptors in brain tissue. Unlike .beta.-endorphin, however, this peptide endorphin does not exhibit respiratory depressor effect when administered to mice. This peptide endorphin can be obtained from placental and pancreatic tissue, preferably by extracting with dilute mineral acid.