Patents by Inventor Charles D. Page

Charles D. Page has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human Pluripotent Stem Cell-Based Models for Predictive Developmental Neural Toxicity
    Publication number: 20220017873
    Abstract: The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.
    Type: Application
    Filed: July 12, 2021
    Publication date: January 20, 2022
    Inventors: James A. Thomson, William L. Murphy, Charles D. Page, Michael P. Schwartz, Zhonggang Hou
  • Human pluripotent stem cell-based models for predictive developmental neural toxicity
    Patent number: 11060066
    Abstract: The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: July 13, 2021
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: James A. Thomson, William L. Murphy, Charles D. Page, Michael P. Schwartz, Zhonggang Hou
  • HUMAN PLURIPOTENT STEM CELL-BASED MODELS FOR PREDICTIVE DEVELOPMENTAL NEURAL TOXICITY
    Publication number: 20160186146
    Abstract: The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.
    Type: Application
    Filed: December 31, 2015
    Publication date: June 30, 2016
    Inventors: James A. Thomson, William L. Murphy, Charles D. Page, Michael P. Schwartz, Zhonggang Hou
  • System and Method for Dynamically Adaptable Learning Medical Diagnosis System
    Publication number: 20100063947
    Abstract: A system and method for determining a likelihood of a disease presence in a particular patient includes a patient history database containing records. Each record includes a plurality of data fields related to a particular patient. An analyzing network is provided having access to the patient history database and having features based on the plurality of data fields included in the records to analyze the plurality of data fields and determine a likelihood of disease presence based on the plurality of features. A learning network is provided that has access to the analyzing network to review the likelihood of disease presence determined by the analyzing network and the plurality of data fields included in the records and automatically identify, evaluate, and add new features to the analyzing network that improve determinations of a likelihood of the disease.
    Type: Application
    Filed: May 15, 2009
    Publication date: March 11, 2010
    Inventors: Elizabeth S. Burnside, Charles D. Page, Jesse J. Davis, Vitor Manuel de Morais Santos Costa