Abstract: A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods for producing novel cryptophycins from the Nostoc sp. of blue-green algae (cyanobacteria). Pharmaceutical compositions comprising novel cryptophycins are also provided, as are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells. Further provided are methods for using cryptophycins to inhibit the proliferation of hyperproliferative cells with drug resistant phenotypes, and to treat pathological conditions, such as neoplasia.

Abstract: Dendroamide derivatives are disclosed which are useful in cancer therapy, especially in treating multidrug resistant cells.

Abstract: Novel scytophycin compounds and compositions are disclosed, along with methods of making and using the new compounds. Methods for preparing the new scytophycin compounds from new strains of the blue-green algae Scytonema ocellatum, Scytonema burmanicum and purified cultures of the algae are also provided. The scytophycins are useful as anti-cancer agents, antifungal agents and for cell research purposes.

Abstract: A mechanism for positioning a cutting and punching machine relative to a fixed conveyor for feeding material to be processed in a fixed horizontal route into the machine. The positioning mechanism comprises a carriage which supports the machine for back and forth movement laterally of the horizontal feeding route, which carriage is supported in turn on a support providing tracks for lateral movement of the carriage, with the support mounted within a lined pit. A drive unit is mounted on the machine for effecting lateral movement of the carriage, and a second drive unit is mounted within the lined pit below the support for moving the support vertically within the pit.