Patents by Inventor Charles D. Warner

Charles D. Warner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cationic lipid acid salt of 3beta?N- (N', N'-dimethylaminoethane) - carbamoyl!cholestrol and halogenated solvent-free preliposomal lyophilate thereof
    Patent number: 5753262
    Abstract: This invention discloses a novel cationic lipid acid salt of 3.beta.?N-(N',N'-dimethylaminoethane)-carbamoyl!cholesterol. This invention further discloses a transmembrane compatible body suitable for transfection of animals and animal cells with nucleotides such as DNA, RNA, and synthetic nucleotides. Such transmembrane compatible bodies arise from hydratable non-liposomal halogenated solvent-free lyophilate comprising 3.beta.?N-(N',N'-dimethylaminoethane)-carbamoyl!cholesterol and DOPE. This invention yet further discloses a halogenated solvent-free aqueous solution, suitable for lyophilization into a preliposomal powder, wherein the solution comprises 3.beta.?N-(N',N'-dimethylaminoethane)-carbamoyl!cholesterol wherein substantially all 3.beta.?N-(N',N'-dimethylaminoethane)-carbamoyl!cholesterol is dissolved.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 19, 1998
    Assignee: Aronex Pharmaceuticals, Inc.
    Inventors: Joseph W. Wyse, Charles D. Warner