Patents by Inventor Charles E. Brown

Charles E. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210052853
    Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a housing; a catheter shaft and an actuator coupled to the catheter shaft and configured to move longitudinally relative to the housing and longitudinally move the catheter shaft in response to force imparted by a user. The apparatuses, systems, and methods may also include a piston assembly arranged within the housing and configured to receive the actuator and allow longitudinal movement of the actuator relative to the housing.
    Type: Application
    Filed: August 20, 2020
    Publication date: February 25, 2021
    Inventors: Charles A. Gibson, Charles E. Brown
  • Publication number: 20210030260
    Abstract: A medical instrument may comprise a first articulatable segment having a first diameter, and a second articulatable segment having a second diameter smaller than the first diameter, wherein the second articulatable segment is coupled to the first articulatable segment and extends in a distal direction past the first articulatable segment. The instrument may also comprise a first force transmission element coupled to the first articulatable segment and extending in a proximal direction from the first articulatable segment to a first connector portion, the first connector portion being configured to be releasably coupled with a first actuator, and a second force transmission element coupled to the second articulatable segment and extending in a proximal direction from the second articulatable segment to a second connector portion, the second connector portion being configured to be releasably coupled with a second actuator.
    Type: Application
    Filed: July 14, 2020
    Publication date: February 4, 2021
    Applicant: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Christopher A. JULIAN, Amir BELSON, Aaron W. BROWN, Mark HARASYM, Marc S. KREIDLER, Robert M. OHLINE, Scott J. REINER, Enrique ROMO, Charles E. SWINEHART, Katherine WHITIN
  • Publication number: 20210025874
    Abstract: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
    Type: Application
    Filed: May 8, 2020
    Publication date: January 28, 2021
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. CRAWFORD, Jillian R. BROWN, Charles A. GLASS, Jim R. BEITEL, Robin M. JACKMAN
  • Publication number: 20210017570
    Abstract: Provided herein are processes for detecting oligosaccharides in a biological sample. In specific instances, the biological sample is provided from an individual suffering from a disorder associated with abnormal glycosaminoglycan accumulation.
    Type: Application
    Filed: May 4, 2020
    Publication date: January 21, 2021
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. CRAWFORD, Jillian R. BROWN, Charles A. GLASS
  • Patent number: 10793894
    Abstract: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: October 6, 2020
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. Crawford, Jillian R. Brown, Charles A. Glass, Jim R. Beitel, Robin M. Jackman
  • Patent number: 10736490
    Abstract: A medical instrument may comprise a first articulatable segment having a first diameter, and a second articulatable segment having a second diameter smaller than the first diameter, wherein the second articulatable segment is coupled to the first articulatable segment and extends in a distal direction past the first articulatable segment. The instrument may also comprise a first force transmission element coupled to the first articulatable segment and extending in a proximal direction from the first articulatable segment to a first connector portion, the first connector portion being configured to be releasably coupled with a first actuator, and a second force transmission element coupled to the second articulatable segment and extending in a proximal direction from the second articulatable segment to a second connector portion, the second connector portion being configured to be releasably coupled with a second actuator.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 11, 2020
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Christopher A. Julian, Amir Belson, Aaron W. Brown, Mark Harasym, Marc S. Kreidler, Robert M. Ohline, Scott J. Reiner, Enrique Romo, Charles E. Swinehart, Katherine Whitin
  • Patent number: 10729116
    Abstract: A pest control and/or detection system generally includes an electrically conductive bait matrix including at least one carrier material that is at least one of palatable, a phagostimulant and/or consumable and/or displaceable by pests, and a plurality of electrically conductive particles. The electrically conductive particles are substantially randomly interspersed throughout the at least one carrier material. The at least one carrier material includes a thermoplastic material and/or a resin.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: August 4, 2020
    Assignee: BASF CORPORATION
    Inventors: James H. Cink, Greggory K. Storey, Kyle K. Jordan, James W. Austin, Charles E. Evanhoe, Bart Ivy, Daniel W. Engels, Daniel Freeman, Kenneth Lauffenburger, Thomas Dills, Kenneth S. Brown, Cheryl Leichter
  • Patent number: 10683530
    Abstract: Provided herein are processes for detecting oligosaccharides in a biological sample. In specific instances, the biological sample is provided from an individual suffering from a disorder associated with abnormal glycosaminoglycan accumulation.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: June 16, 2020
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. Crawford, Jillian R. Brown, Charles A. Glass
  • Patent number: 10677786
    Abstract: Provided herein are methods of diagnosing or monitoring the treatment of mucopolysaccharidosis (MPS) I or a disorder associated with MPS I.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: June 9, 2020
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. Crawford, Jillian R. Brown, Charles A. Glass, Jim R. Beitel, Robin M. Jackman
  • Publication number: 20190249224
    Abstract: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
    Type: Application
    Filed: February 20, 2019
    Publication date: August 15, 2019
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Brett E. CRAWFORD, Jillian R. BROWN, Charles A. GLASS, Jim R. BEITEL, Robin M. JACKMAN
  • Publication number: 20190239499
    Abstract: A pest control and/or detection system generally includes an electrically conductive bait matrix including at least one carrier material that is at least one of palatable, a phagostimulant and/or consumable and/or displaceable by pests, and a plurality of electrically conductive particles. The electrically conductive particles are substantially randomly interspersed throughout the at least one carrier material. The at least one carrier material includes a thermoplastic material and/or a resin.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: James H. CINK, Greggory K. STOREY, Kyle K. JORDAN, James W. AUSTIN, Charles E. EVANHOE, Bart IVY, Daniel W. ENGELS, Daniel FREEMAN, Kenneth LAUFFENBURGER, Thomas DILLS, Kenneth S. BROWN, Cheryl LEICHTER
  • Patent number: 10315135
    Abstract: A conduit assembly of a gravity separation device having specialized joint structure for mating first and second conduits to permit easier removal of the first conduit. The first conduit may include a snout having a tube and a collar positioned at an end of the tube. The collar may include a flange extending outward from a center of the tube. The second conduit may have a main body and a saddle at an end of the main body. The saddle may include a track shaped to receive the flange of the collar of the first conduit. The saddle may also have a resiliently separable gateway comprising two opposing projections configured for receiving therebetween and partially enclosing the tube of the snout.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: June 11, 2019
    Assignee: Schier Products Company
    Inventors: Benjamin F. Brown, Todd E. Uhlenhake, Martin B. Ismert, Charles M. Ismert, Luke J. Ismert
  • Patent number: 7722604
    Abstract: Embodiments of the invention relate to electrophysiology catheters and methods of using the same. According to one embodiment, the catheter includes a braided conductive member at its distal end that can be radially expanded, for example using a mandrel slidably disposed within a shaft of the catheter. According to another embodiment, the catheter comprises a tip portion constructed of an elastomeric material. According to a further embodiment, the catheter includes a braided conductive member wherein a thermocouple is formed using one filament of the braided conductive member and one thermocouple wire. Other embodiments of the invention relate to a handle for use with a catheter and methods of using the same. According to one embodiment, the handle comprises a thumbwheel coupled to a housing, a spring disposed within the housing in contact with the thumbwheel, and means for increasing compression of the spring to increase rotational friction on the thumbwheel.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: May 25, 2010
    Assignee: C.R. Bard, Inc.
    Inventors: Charles E. Brown, III, Amedeo Chiavetta, Peter D. Kozel, Dennis Lamser, Glenn Therriault
  • Publication number: 20040092806
    Abstract: Catheter for mapping and/or ablation, and methods of using the same. According to one embodiment, catheter includes a metallic cap having a plurality of apertures and at least one electrode disposed in each aperture of the plurality of apertures. According to another embodiment, the catheter includes a non-conductive cap having a plurality of apertures and at least one electrode disposed in each aperture of the plurality of apertures. Electrodes may be paired, arranged along the length of the cap, or circumferentially arranged on the cap, according to various embodiments. According to a further embodiment, a method for treating a condition of a heart includes placing a catheter inside the heart, mapping a region of the heart using mapping electrodes on the catheter, and ablating using an ablation electrode disposed about the mapping electrodes of the catheter.
    Type: Application
    Filed: December 12, 2003
    Publication date: May 13, 2004
    Inventors: Stephen W Sagon, Charles E Brown, Charles A Gibson, David MacAdam, Donald F Patterson, Amedeo J Chiavetta
  • Publication number: 20030030211
    Abstract: A game system providing multiple levels of integrated play featuring instant progressive awards and variably compounding award amounts. The game system may be one of many types, including seal cards, jar tickets, instant games and lottery tickets. The game system offers the opportunity for awards at an initial level, and a chance for an instant progressive award offered to players qualifying for an upper level. Players eligible for an instant progressive award do not wait until the end of play at the initial level before participating at the upper level. Any upper level progressive award amounts not awarded may be compounded with an award amount associated with the next round of play to create an increased award amount in the next round. Any compounded award amount is variable and not predetermined. The instant progression scheme and variably compounding award amounts increase player interest over multiple rounds of play.
    Type: Application
    Filed: August 5, 2002
    Publication date: February 13, 2003
    Inventor: Charles E. Brown
  • Patent number: 6390916
    Abstract: A seal card game system providing multiple levels of non-progressive play. The game system awards a master case award to a winning ticket not among the population of individual deal winning tickets. A winning ticket of each deal set does not qualify for the master case award level. The game features segregated deal sets, each set containing break-open tickets. Each deal set is segregated by deal identifier indicia. In one exemplary embodiment, the deal identifier indicia is a selected color which is imprinted on each of the playing tickets comprising a deal set. The play tickets may be serialized by deal or by case for security. A seal card may includes the serialization of each ticket associated with the case. The non-progression scheme benefits the game operator in retaining the interest and participation of a higher population of players throughout the multiple deal play.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: May 21, 2002
    Inventor: Charles E. Brown
  • Patent number: 6032065
    Abstract: A flexible, lightweight, inexpensive, and easy to attach sensor mask (10) for placement on a patient (11) for monitoring physiological signals of the patient is disclosed. The sensor mask includes an elongated flexible substrate (12); a plurality of electrodes (14) spaced along the length of the substrate and configured for placement against the patient for sensing the physiological signals; and at least one electrical connector (16) electrically coupled with the electrodes for delivering the physiological signals sensed by the electrodes to a recording/analyzing device. The electrodes are formed of patches of conductive ink that are deposited on the substrate at spaced locations along the length thereof. The electrical connector includes terminals formed of conductive ink deposited on the substrate and is electrically coupled with the electrodes by a plurality of lines of conductive ink deposited on the substrate.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: February 29, 2000
    Assignee: Nellcor Puritan Bennett
    Inventor: Charles E. Brown
  • Patent number: 5904053
    Abstract: A refrigeration system includes an evaporator coil with a drain pan having alternative drain openings which receive movable primary and secondary drain plugs. A drain pan for use with horizontal A-coils is provided with alternative drain pan openings permitting a variety of configurations whereby the evaporator coil may be oriented in the space conditioning system in the most effective manner depending upon on-site conditions. A combination horizontal coil support and drainage duct with coil baffle provides a channel for effective communication of drainage fluid from the coil to the drain pan.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: May 18, 1999
    Assignee: International Comfort Products
    Inventors: Gregory A. Polk, Andy L. Derryberry, Steve Brady, Cos Caronna, Timothy P. O'Leary, Clarence D. Cash, Louis R. Goodman, Charles E. Brown, Jr.
  • Patent number: 5280661
    Abstract: A digital wipe device is provided for lenses and similar articles which consists of a pair of sheaths in which the first sheath fits on a thumb of a hand and the second sheath fits on a finger of the hand. An interconnecting flexible member is connected to and extends between one side of each of the sheaths. A plurality of wiping sheets are connected in a stacked manner to an underside of the interconnecting flexible member and the sheaths, so that the outermost wiping sheet can be used to clean the lenses and similar articles between the thumb and finger and than torn away when soiled to expose a fresh clean wiping sheet for further use.
    Type: Grant
    Filed: November 2, 1992
    Date of Patent: January 25, 1994
    Inventor: Charles E. Brown
  • Patent number: 4746302
    Abstract: An insulating bolt is disclosed herein for use in supporting signs on walls comprising a hollow threaded shaft having a channel disposed on the shaft to receive a grounding strap which is laid in the channel. The end of the grounding strap conforms to the end of the shaft of the bolt for engaging into the end of an armored cable thus providing grounding means from the sign back to the power source. A slide locking nut having a raised shoulder for sliding in the channel is provided for positioning and holding the bolt in place.
    Type: Grant
    Filed: December 22, 1986
    Date of Patent: May 24, 1988
    Inventor: Charles E. Brown