Abstract: An exercise machine for leg strengthening, the exercise machine comprising a stationary frame; and a thigh support member and an ankle support member coupled to the frame and configured to support a user's thigh and ankle, respectively, during a hamstring curl exercise motion. The thigh support member and the ankle support member are each movable with respect to the stationary frame during the hamstring curl exercise motion, thus facilitating contraction and extension of both of a hamstring and glute of the user during the hamstring curl exercise motion.

Abstract: An exercise machine for leg strengthening, the exercise machine comprising a stationary frame; and a thigh support member and an ankle support member coupled to the frame and configured to support a user's thigh and ankle, respectively, during a hamstring curl exercise motion. The thigh support member and the ankle support member are each movable with respect to the stationary frame during the hamstring curl exercise motion, thus facilitating contraction and extension of both of a hamstring and glute of the user during the hamstring curl exercise motion.

Abstract: Methods are provided for treating HIV and cancer in a subject in need thereof by administering to the subject therapeutically effective amounts of an mTOR inhibitor. Other methods are provided for treating subjects infected with HIV by administering to the subject therapeutically effective amounts of the mTOR inhibitor INK128, GSK2126458, AZD2014 or Torin-2.

Abstract: An integrated inventory control and security method for multiple types of articles which are for sale within retail premises accounts for entry of articles into the retail premises and removal of articles from the retail premises, including documenting certain events.

Abstract: An integrated inventory control and security system for multiple types of articles which are for sale within retail premises to account for entry of articles into retail premises and removal (both authorized removal and attempted unauthorized removal) of articles from retail premises, including a method of documenting events which disclose attempted unauthorized removal of articles.

Abstract: An integrated inventory control and security system for multiple types of articles which are for sale within retail premises to account for entry of articles into retail premises and removal (both authorized removal and attempted unauthorized removal) of articles from retail premises, including a method of documenting events which disclose attempted unauthorized removal of articles.

Abstract: A system and method for securing premises by distinguishing between authorized and unauthorized removal of articles from the premises via an approach within the premises to an exit door (38). Each article is secured by a passive security device (50) which in an article-securing state will be detected upon the article entering the approach and in a non-securing state will not be wirelessly detected upon the article entering the approach. A detector (40), having a detection transmitter and a receiver, wirelessly detects attempted unauthorized removal of a secured article. A register (36) registers authorized removal of a secured article. An unsecuring transmitter (52) is controlled by the register to wirelessly transmit to a passive security device of a secured article whose authorized removal has been registered in the register, an unsecuring signal which unsecures the secured article by changing the passive security device from the article-securing state to the non-securing state.

Abstract: Systems and method of processing one or more documents are shown and described. The orientation of a magnetic character is sensed on the document. The orientation is processed and used to control a sort processing device.

Abstract: A system and method for securing premises by distinguishing between authorized and unauthorized removal of articles from the premises via an approach within the premises to an exit (38). Each article is secured by a passive security device (50) which in an article-securing state will be detected upon the article entering the approach and in a non-securing state will not be wirelessly detected upon the article entering the approach. A detector (40), having a detection transmitter and a receiver, wirelessly detects attempted unauthorized removal of a secured article. A register (36) registers authorized removal of a secured article. An unsecuring transmitter (52) is controlled by the register to wirelessly transmit to a passive security device of a secured article whose authorized removal has been registered in the register, an unsecuring signal which unsecures the secured article by changing the passive security device from the article-securing state to the non-securing state.

Abstract: The present invention relates to the downregulation of surface receptor CCR5 expression through manipulation of the cell cycle in activated lymphocytes by administering a composition that arrests the G1 phase of the cell cycle, thereby reducing receptor sites for entry of HIV into T cells, and thus, the effects of HIV. Further, compositions are disclosed that include at least one G1 phase arresting agent and at least one antiviral agent, wherein the combination of agents synergistically enhances the activity of the antiviral agent.

Abstract: Systems and method of processing one or more documents are shown and described. The orientation of a magnetic character is sensed on the document. The orientation is processed and used to control a sort processing device.

Abstract: A comprehensive system and method of rendering the mail safe for handling and for detecting and containing suspect pieces and which can be fitted or retrofitted into mail and package processing facilities with relative ease. The system of the present invention includes a mail tray initial neutralizing sub-system, a subsequent neutralizing sub-system, an analyzing (potentially hazardous material detection) sub-system, a diverting mechanism, and a receiving and holding sub-system (secure out-sort pocket). All components can be controlled or operate in conjunction with a processing/computing sub-system. A feeder sub-system provides the mail from trays, after initial neutralization by the initial neutralizing sub-system, to the mail transport system.

Abstract: A method of detecting a member of the taxa actinomycetos is provided. A method also is provided for detecting mycothiol or precursor thereof. An antibody is provided which binds to mycothiol or a mycothiol precursor. A method is further provided for diagnosis of a subject having or at risk of having an actinomycetes-associated disorder. A method is also provided for identifying a sample with altered production of mycothiol or a precursor thereof. A method is provided for detecting mycothiol or precursor thereof in a bacterial colony. Kits are also disclosed which arc useful for detecting the presence of mycothiol or precursor thereof in a sample.

Abstract: The present invention provides methods and systems for the application of the analysis of radiation interactions to early detection hazardous material. The method, in a mail processing system, includes the steps of: (a) positioning one or more sensors, a sensor including a radiation source, a detector and the analysis instructions in the computing unit, along the path of a transport system for processing the mail, (b) sensing the presence of a hazardous material in a mail piece, and (c) culling the mail piece, if the presence of hazardous material is detected where culling includes, but not limited to, one or more of the following: diverting to a secure pocket and alerting, removing from the processing stream, alerting and interrupting the processing stream in order to remove an item, diverting the item from the processing stream for further inspection.

Abstract: A comprehensive system and method of rendering the mail safe for handling and for detecting and containing suspect pieces and which can be fitted or retrofitted into mail and package processing facilities with relative ease. The system of the present invention includes a mail tray initial neutralizing sub-system, a subsequent neutralizing sub-system, an analyzing (potentially hazardous material detection) sub-system, a diverting mechanism, and a receiving and holding sub-system (secure out-sort pocket). All components can be controlled or operate in conjunction with a processing/computing sub-system. A feeder sub-system provides the mail from trays, after initial neutralization by the initial neutralizing sub-system, to the mail transport system.

Abstract: Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly effective where the subject has resistance to a nucleoside analogue, where the subject has resting cellular reservoirs of such a virus, or to induce a post-treatment period of replication incompetence of such a virus.

Abstract: An assembly for applying hot melt adhesive to the backbone of a book block to attach a cover includes a bath of hot melt glue heated to approximately 350.degree. F. A metal wheel is submerged in the bath. The metal wheel is rotated and scrapers meter the hot melt adhesive on the surface of the metal wheel. The metal wheel transfers the hot melt adhesive to flexible adhesive distribution wheel. The flexible wheel is fabricated of a silicone rubber with iron oxide capable of withstanding the elevated temperatures of the hot melt adhesive while maintaining its flexibility. In addition, the cut and mold of the wheel results in greater flexibility of the wheel, allowing the wheel to flex to engage completely the backbone of each book block to apply the adhesive fully and completely.

Abstract: An electromagnetic propulsion system based on an extremely low frequency (elf) radiating antenna structure driven by a matched high current pulsed power supply is described. The elf antenna structure resembles a modified three dimensional multiple-turn loop antenna whose geometry is optimized for the production of reaction thrust rather than the radiation of electromagnetic energy into space. The antenna structure is current driven rather than voltage drive. Rigid three dimensional geometric asymmetry, made up of flat electrical conductors that form a partially closed volume in the loop antenna structure, trap magnetic flux thereby causing a magnetic field density gradient along a single axis. This magnetic field density gradient then causes an imbalance in the magneto- mechanical forces that normally result from the interactions of the loop antenna's internal magnetic field with the current in the conductors of the loop antenna structure, as described by the Lorentz Force Law.

Abstract: A color grading scale comprises a plurality of individual cast resin chips, each representative of a single color, with the chips attached one to another to form a continuous array of color chips. In a preferred form, the chips are incorporated into a linear slide which fits within a groove formed in a surface of a frame. The frame is formed of a plastic material having a bright white color for maximum white light reflection. Formed in the frame adjacent to and spaced from the groove is at least one shallow pocket having a depth substantially the same as the groove for receiving a gemstone to be color graded by comparison to the color chips of the slide. Plural pockets of different sizes may be provided to accommodate different size stones.

Abstract: A quick change wheel landing gear assembly (10) is provided as a replacement for a skid landing gear system on a vertical take-off and landing aircraft. The wheel landing gear assembly (10) includes a pair of spaced-apart fore and aft longitudinal tubes (16, 18) attached to a pair of short, spaced-apart cross tubes (20, 22) that are adapted to mount on the structural saddles (12, 14) used to mount the skid landing gear on the underside of the aircraft. The longitudinal tubes (16, 18) are connected together at the forward end for mounting a fully swiveling nose gear (26) thereto. Aft main gear wheels (30, 32) are mounted on cantilever landing gear legs (34, 36) that extend laterally from the longitudinal tubes (16, 18) adjacent the aft cross tube (22). Landing loads on the landing gear may be absorbed by resilient springs (25), deflection of the gear legs (34, 36) and the aft cross tube (22), torsion of the fore and aft longitudinal tubes (16, 18), or any combination of these actions.