Patents by Inventor Charles E. Sing

Charles E. Sing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for detecting molecular interactions using magnetic beads
    Patent number: 9977015
    Abstract: Systems and methods are provided for detecting or measuring binding affinity between different compositions. The methods include contacting one or more magnetic beads having a surface including a first composition with a substrate having a surface including a second composition; applying a rotating magnetic field to the one or more magnetic beads effective to cause the one or more magnetic beads to move across the surface of the substrate; measuring the movement of the one or more magnetic beads across the substrate surface to determine a translational velocity; and determining a binding affinity between the first and second compositions from the translational velocity.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: May 22, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Charles E. Sing, Joshua P. Steimel, Alfredo Alexander-Katz
  • SYSTEMS AND METHODS FOR DETECTING MOLECULAR INTERACTIONS USING MAGNETIC BEADS
    Publication number: 20150147821
    Abstract: Systems and methods are provided for detecting or measuring binding affinity between different compositions. The methods include contacting one or more magnetic beads having a surface including a first composition with a substrate having a surface including a second composition; applying a rotating magnetic field to the one or more magnetic beads effective to cause the one or more magnetic beads to move across the surface of the substrate; measuring the movement of the one or more magnetic beads across the substrate surface to determine a translational velocity; and determining a binding affinity between the first and second compositions from the translational velocity.
    Type: Application
    Filed: May 15, 2013
    Publication date: May 28, 2015
    Applicant: Massachusetts Instiute of Technology
    Inventors: Charles E. Sing, Joshua P. Steimel, Alfredo Alexander-Katz