Patents by Inventor Charles Edward Wade

Charles Edward Wade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes
    Patent number: 9725420
    Abstract: This invention relates to methods of making a compound of formula (I) and intermediates for same the compounds of formula (I) being useful for treating cardiovascular and inflammatory diseases such as atherosclerosis.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: August 8, 2017
    Assignee: Glaxo Group Limited
    Inventors: Kevin Stuart Cardwell, Claire Frances Crawford, Suzanne Helen Davies, Charles Edward Wade
  • NOVEL PROCESSES
    Publication number: 20160347720
    Abstract: This invention relates to methods of making a compound of formula (I) and intermediates for same the compounds of formula (I) being useful for treating cardiovascular and inflammatory diseases such as atherosclerosis.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 1, 2016
    Inventors: Kevin Stuart CARDWELL, Claire Frances CRAWFORD, Suzanne Helen DAVIES, Charles Edward WADE
  • Processes for preparing pyrimidine compounds
    Patent number: 9447052
    Abstract: This invention relates to methods of making a compound of formula (I) and intermediates for same the compounds of formula (I) being useful for treating cardiovascular and inflammatory diseases such as atherosclerosis.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: September 20, 2016
    Assignee: Glaxo Group Limited
    Inventors: Kevin Stuart Cardwell, Claire Frances Crawford, Suzanne Helen Davies, Charles Edward Wade
  • NOVEL PROCESSES
    Publication number: 20130060028
    Abstract: This invention relates to methods of making a compound of formula (I) and intermediates for same the compounds of formula (I) being useful for treating cardiovascular and inflammatory diseases such as atherosclerosis.
    Type: Application
    Filed: May 17, 2011
    Publication date: March 7, 2013
    Inventors: Kevin Stuart Cardwell, Claire Frances Crawford, Suzanne Helen Davies, Charles Edward Wade
  • Quinoline derivatives and their use as 5-HTligands
    Patent number: 8236947
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 7, 2012
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20110237792
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Johnes, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-HT6 ligands
    Patent number: 7977337
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: July 12, 2011
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20100305107
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Application
    Filed: July 30, 2010
    Publication date: December 2, 2010
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-HTligands
    Patent number: 7799774
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: September 21, 2010
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20090298841
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: August 14, 2009
    Publication date: December 3, 2009
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline Derivatives and Their Use as 5-HT6 Ligands
    Publication number: 20090036682
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: September 5, 2008
    Publication date: February 5, 2009
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-ht6 ligands
    Patent number: 7452888
    Abstract: Disclosed are novel quinoline compounds of formula (I), processes for their preparation, compositions containing them and their use in the treatment of CNS disorders.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: November 18, 2008
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James Macdonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • Novel Chemical Process For the Synthesis of Quinoline Compounds
    Publication number: 20080255359
    Abstract: Disclosed is a novel, simplified and economic process for making 3-phenylsulphonyl quinolines with an amine group at position 8 of the quinoline ring system, including 3-phenylsulfonyl-8-piperazin-1-yl-quinoline in particular, in the absence of a palladium catalyst. Also disclosed is the crystallization of polymorphic forms of 3-phenylsulfonyl-8-piperazin-1-yl-quinoline.
    Type: Application
    Filed: September 26, 2006
    Publication date: October 16, 2008
    Inventor: Charles Edward Wade