Patents by Inventor Charles Elliott Sigal

Charles Elliott Sigal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted gene expression using preproendothelin-1 promoters
    Patent number: 5747340
    Abstract: This invention provides a vector for expression of a nucleic acid cassette in bronchial epithelial and vascular endothelial cells comprising a segment of the 5'-flanking region of the preproendothelin-1 gene, upstream from the transcription start site, the first exon of the preproendothelin-1 gene, and a nucleic acid cassette, wherein the nucleic acid cassette is located within the first exon, in sequential and positional relationship for expression of the nucleic acid cassette.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: May 5, 1998
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Dror Harats, Hiroki Kurihara, Paula Nanette Belloni, Charles Elliott Sigal