Patents by Inventor Charles Esmon

Charles Esmon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating hemophilia using monoclonal antibodies against activated protein C
    Patent number: 9127072
    Abstract: The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: September 8, 2015
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Jun Xu, Charles Esmon
  • Monoclonal Antibodies Against Activated Protein C
    Publication number: 20120164150
    Abstract: The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.
    Type: Application
    Filed: November 29, 2011
    Publication date: June 28, 2012
    Inventors: Jun XU, Charles ESMON
  • Monoclonal antibodies against activated protein C
    Patent number: 8153766
    Abstract: The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: April 10, 2012
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Jun Xu, Charles Esmon
  • MONOCLONAL ANTIBODIES AGAINST ACTIVATED PROTEIN C
    Publication number: 20090110683
    Abstract: The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.
    Type: Application
    Filed: October 24, 2008
    Publication date: April 30, 2009
    Inventors: Jun Xu, Charles Esmon