Abstract: A system and method of magnetic particle imaging (MPI) are disclosed. The system and method use ultrasound to drive magnetic particles (such as nanoparticles) through a magnetic field gradient to generate a signal and map the magnetic particles' distribution or concentration.

Abstract: A workflow has been developed that enables initially mapping of a focused ultrasound (FUS) beam using magnetic resonance (MR) thermometry or MR-acoustic radiation force imaging (MR-ARFI) while working within the MRI device. During this procedure, key measurements will be taken including the precise location of the transducer relative to the skull and the transducer parameters (such as amplitudes and phases) required to place the ultrasound focus at the desired focal size and location in the skull. The anatomical measurements will be used to build a patient-specific, device-specific stereotactic frame to hold the transducer in the position relative to the skull and the aberration corrects will be applied. FUS therapy can then be delivered to the patient outside of the MR environment.

Abstract: A system and method of magnetic particle imaging (MPI) are disclosed. The system and method use ultrasound to drive magnetic particles (such as nanoparticles) through a magnetic field gradient to generate a signal and map the magnetic particles' distribution or concentration.

Abstract: A system and method of magnetic particle imaging (MPI) are disclosed. The system and method use ultrasound to drive magnetic particles (such as nanoparticles) through a magnetic field gradient to generate a signal and map the magnetic particles' distribution or concentration.

Abstract: Applications related to non-invasive magnetic resonance guided focused ultrasound (MRgFUS) in a patient's vasculature are described. For example, the applications can include an ablation procedure, an occlusion procedure, a cauterization procedure, and the like. Accordingly, one aspect of the present disclosure is directed to a method for performing an MRgFUS application that includes selecting a target area within a patient's vasculature, configuring multifocal acoustic waves, and applying the multifocal acoustic waves to the target area to heat sequential locations in the target area simultaneously to facilitate the MRgFUS application.