Patents by Inventor Charles F. Grose

Charles F. Grose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Variant varicella-zoster viruses and methods of use
    Patent number: 6843997
    Abstract: The present invention provides methods directed to detecting antibodies that specifically bind to a varicella zoster polypeptide, detecting the presence of a varicella zoster virus in an animal, diagnosing a disease caused by varicella zoster virus, and detecting a varicella zoster virus having a single nucleotide polymorphism in ORF68. The present invention also provides a vaccine composition, a method for producing a modified attenuated varicella zoster virus, isolated polynucleotides, and isolated polypeptides, and viruses.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: January 18, 2005
    Assignee: University of Iowa Research Foundation
    Inventors: Charles F. Grose, Richard Santos
  • Variant varicella-zoster viruses and methods of use
    Publication number: 20030166168
    Abstract: The present invention provides methods directed to detecting antibodies that specifically bind to a varicella zoster polypeptide, detecting the presence of a varicella zoster virus in an animal, diagnosing a disease caused by varicella zoster virus, and detecting a varicella zoster virus having a single nucleotide polymorphism in ORF68. The present invention also provides a vaccine composition, a method for producing a modified attenuated varicella zoster virus, isolated polynucleotides, and isolated polypeptides, and viruses.
    Type: Application
    Filed: November 6, 2002
    Publication date: September 4, 2003
    Applicant: University of Iowa Research Foundation
    Inventors: Charles F. Grose, Richard Santos
  • Variant varicella-zoster viruses and methods of use
    Patent number: 6528066
    Abstract: The present invention provides methods directed to detecting antibodies that specifically bind to a varicella zoster polypeptide, detecting the presence of a varicella zoster virus in an animal, diagnosing a disease caused by varicella zoster virus, and detecting a varicella zoster virus having a single nucleotide polymorphism in ORF68. The present invention also provides a vaccine composition, a method for producing a modified attenuated varicella zoster virus, isolated polynucleotides, and isolated polypeptides, and viruses.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: March 4, 2003
    Assignee: University of Iowa Research Foundation
    Inventors: Charles F. Grose, Richard Santos
  • Peptide tag for immunodetection and immunopurification
    Patent number: 6255462
    Abstract: This invention discloses the incorporation of a peptide QRQYGDVFKGD (SEQ ID NO:1) from glycoprotein gE of Varicella zoster virus into a protein or polypeptide sequence for immunoisolation, immunopurification and immunodetection.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: July 3, 2001
    Assignee: University of Iowa Research Foundation
    Inventor: Charles F. Grose
  • Peptide tag for immunodetection and immunopurification
    Patent number: 5710248
    Abstract: This invention discloses the incorporation of a peptide QRQYGDVFKGD (SEQ ID NO:1) from glycoprotein gE of Varicella zoster virus into a protein or polypeptide sequence for immunoisolation, immunopurification and immunodetection.
    Type: Grant
    Filed: July 29, 1996
    Date of Patent: January 20, 1998
    Assignee: University of Iowa Research Foundation
    Inventor: Charles F. Grose