Patents by Inventor Charles F. Louis

Charles F. Louis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnosing malignant hyperthermia susceptibility by detection of abnormal proteolytic enzyme digestion fragments of the ryanodine receptor
    Patent number: 5462857
    Abstract: The present invention relates to a method of diagnosing malignant hyperthermia susceptibility by detecting abnormal ryanodine receptor fragments following proteolytic enzyme digestion of ryanodine receptors isolated from the sarcoplasmic reticulum of mammalian skeletal muscle. The detection of abnormal ryanodine receptor fragments is indicative of malignant hyperthermia susceptibility.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: October 31, 1995
    Assignee: University of Iowa Research Foundation
    Inventors: Kevin P. Campbell, C. Michael Knudson, Steven D. Kahl, Charles F. Louis, James R. Mickelson
  • Diagnosing malignant hyperthermia susceptibility by detection of abnormal proteolytic enzyme digestion fragments of the ryanodine receptor
    Patent number: 5242801
    Abstract: The present invention relates to a method of diagnosing malignant hyperthermia susceptibility by detecting abnormal ryanodine receptor fragments following proteolytic enzyme digestion of ryanodine receptors isolated from the sarcoplasmic reticulum of mammalian skeletal muscle. The detection of abnormal ryanodine receptor fragments is indicative of malignant hyperthermia susceptibility.
    Type: Grant
    Filed: August 6, 1990
    Date of Patent: September 7, 1993
    Assignees: University of Iowa Research Foundation, Regents of the University of Minnesota
    Inventors: Kevin P. Campbell, C. Michael Knudson, Steven D. Kahl, Charles F. Louis, James R. Mickelson