Patents by Inventor Charles F. Schwender

Charles F. Schwender has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868200
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 9, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868199
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 9, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868195
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868205
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Substituted thiacycloalkeno [3,2-b] pyridines
    Patent number: 4845225
    Abstract: Novel substituted thiacycloalkeno [3,2-b] pyridines are described. These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstrictor activity.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: July 4, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Charles F. Schwender, John H. Dodd
  • Purine derivatives
    Patent number: 4806642
    Abstract: Novel purine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions as well as novel intermediates in the manufacture thereof.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: February 21, 1989
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Charles F. Schwender, Mark J. Suto
  • Pharmaceutically useful substituted thiacycloalkeno [3,2-b]pyridines, compositions and method of use
    Patent number: 4777167
    Abstract: Novel substituted thiacycloalkeno [3,2-b]pyridines are described. These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstrictor activity.
    Type: Grant
    Filed: February 17, 1987
    Date of Patent: October 11, 1988
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Charles F. Schwender, John H. Dodd
  • Enolamides, pharmaceutical compositions and methods for treating inflammation
    Patent number: 4761424
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: October 1, 1985
    Date of Patent: August 2, 1988
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Guanine derivatives
    Patent number: 4748177
    Abstract: Novel guanine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: May 31, 1988
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Catherine R. Brungardt, Charles F. Schwender
  • Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
    Patent number: 4711883
    Abstract: Novel substituted-3-(4-phenyl-1-piperazinyl)alkyl quinazolin-2,4-(1H,3H)diones are described. These compounds are useful as antihypertensive agents.
    Type: Grant
    Filed: September 30, 1985
    Date of Patent: December 8, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Charles F. Schwender, Robert Falotico, Alfonso J. Tobia
  • Substituted thiacycloalkeno (3,2-b) pyridines and pharmaceutical compositions and method of use
    Patent number: 4705785
    Abstract: Novel substituted thiacycloalkeno [3,2-b] pyridines are described. These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstrictor activity.
    Type: Grant
    Filed: April 9, 1986
    Date of Patent: November 10, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Charles F. Schwender, John H. Dodd
  • Substituted 5,6-dialkoxyquinazoline derivatives
    Patent number: 4672116
    Abstract: Quinazoline derivatives having an oxy substituent in 5 and 6 positions are described. The novel quinazoline derivatives are useful as cardiotonic agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: June 9, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, John H. Dodd, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • 5,6-dialkoxy-4-imino-2(1H)quinazolinone derivatives
    Patent number: 4668787
    Abstract: Quinazolinone derivatives having an oxy substituent in the 5- and 6-positions are disclosed. The quinazolinone derivatives are useful as cardiovascular agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: May 26, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • 3-[2-(Azabicyclo) ethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones
    Patent number: 4404138
    Abstract: Anticholinergic 3-[2-(azabicyclo)ethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin -5-ones useful for treating bronchospastic diseases in mammals are disclosed. Also disclosed are methods for preparing said compounds, pharmaceutical compositions containing them and methods for using said pharmaceutical compositions.
    Type: Grant
    Filed: June 22, 1982
    Date of Patent: September 13, 1983
    Assignee: Warner-Lambert Company
    Inventors: David T. Connor, Charles F. Schwender, Roderick J. Sorenson, Paul C. Unangst
  • 3-[2-(Mono-and dialkylamino)propyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-C]pyridin- 5-ones useful for treating bronchospastic diseases
    Patent number: 4382939
    Abstract: Anticholinergic 3-[2-(mono- and dialkylamino)-propyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]-pyridin- 5-ones useful for treating bronchospastic diseases in mammals are disclosed. Also disclosed are methods for preparing said compounds, pharmaceutical compositions containing them and methods for using said pharmaceutical compositions.A method for preparing the intermediate which is required to prepare the unsubstituted benzopyrano-[3,4-c]pyridin-5-ones of the invention is also disclosed.
    Type: Grant
    Filed: February 23, 1982
    Date of Patent: May 10, 1983
    Assignee: Warner Lambert Company
    Inventors: David T. Connor, Charles F. Schwender, Roderick J. Sorenson, Paul C. Unangst
  • Substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic acids
    Patent number: 4250177
    Abstract: The invention relates to substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic acids having the formula: ##STR1## wherein R.sub.1 is hydrogen, halogen; R.sub.2 is hydrogen, lower alkyl containing one to three carbon atoms, or wherein R.sub.1 and R.sub.2 taken together with the carbon atoms to which they are attached in a benzo ring, and the pharmaceutically acceptable salts thereof. These compounds are useful as anti-allergic agents.
    Type: Grant
    Filed: January 21, 1980
    Date of Patent: February 10, 1981
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Brooks R. Sunday
  • (Substituted 2-carboxyanilino)nicotinic acids as inhibitors of allergic reactions
    Patent number: 4179509
    Abstract: The present invention relates to (substituted 2-carboxyanilino) nicotinic acids which have the capability of inhibiting allergic reactions.
    Type: Grant
    Filed: September 18, 1978
    Date of Patent: December 18, 1979
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Brooks R. Sunday
  • Benzo[g]pyrido[2,1-b]quinazolinones
    Patent number: 4142049
    Abstract: Disclosed are novel benzo[g]Pyrido[2,1-b]-quinazolinones which are active as anti-allergy agents and thus have utility in the treatment of allergic reactions such as bronchial asthma.
    Type: Grant
    Filed: December 5, 1977
    Date of Patent: February 27, 1979
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Brooks R. Sunday
  • 1,2-Benzoxathiin-2,2,-dioxides
    Patent number: 4116961
    Abstract: Disclosed are substituted 1,2-benzoxathin-2,2-dioxide, and methods for their manufacture. These compounds show antiinflammatory activity.
    Type: Grant
    Filed: February 24, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Brooks R. Sunday
  • Method of inhibiting gastric acid secretions with 2-(4-pyrimidinyl)thioacetamides
    Patent number: 4117131
    Abstract: 2-(4-Pyrimidinyl)thioacetamides are disclosed that have been found useful in the treatment of gastric hyperacidity.
    Type: Grant
    Filed: September 12, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Russell E. Pike