Patents by Inventor Charles F. Simmons

Charles F. Simmons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic biomarker to predict women at risk for preterm delivery
    Patent number: 10545156
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers including but not limited to cytokines, cytokine receptors, cytokine receptor antagonists, chemokines, chemokine receptors, and/or chemokine receptor antagonists found in women that are at risk for preterm delivery. The diagnostic methods may be performed on whole blood.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: January 28, 2020
    Assignee: RPI Consulting, LLC
    Inventors: Ozlem Equils, Charles F. Simmons
  • DIAGNOSTIC BIOMARKER TO IDENTIFY WOMEN AT RISK FOR PRETERM DELIVERY
    Publication number: 20180038871
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.
    Type: Application
    Filed: August 22, 2017
    Publication date: February 8, 2018
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem EQUILS, Charles F. SIMMONS, JR.
  • Diagnostic Biomarker to Predict Women at Risk for Preterm Delivery
    Publication number: 20160077102
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers including but not limited to cytokines, cytokine receptors, cytokine receptor antagonists, chemokines, chemokine receptors, and/or chemokine receptor antagonists found in women that are at risk for preterm delivery. The diagnostic methods may be performed on whole blood.
    Type: Application
    Filed: November 19, 2015
    Publication date: March 17, 2016
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem Equils, Charles F. Simmons
  • DIAGNOSTIC BIOMARKER TO IDENTIFY WOMEN AT RISK FOR PRETERM DELIVERY
    Publication number: 20160069891
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.
    Type: Application
    Filed: August 26, 2015
    Publication date: March 10, 2016
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem EQUILS, Charles F. SIMMONS
  • Caspase inhibitors in the treatment of infection-associated preterm delivery
    Patent number: 8828950
    Abstract: Apoptotic processes induced by infection of, or injury to, fetal and placental tissues have been implicated in preterm delivery. Thus, modulation of apoptotis constitutes a strategy for improving pregnancy outcome in women with intrauterine infections. Caspase inhibitors, including the pancaspase inhibitor Z-VAD-FMK, can be used to prevent apoptosis and, thus, prevent preterm delivery. Accordingly, compositions and methods comprising caspase inhibitors for prevention of preterm delivery are provided.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: September 9, 2014
    Assignee: Cedars-Sinai Medical Center
    Inventors: Ozlem Equils, Calvin Hobel, Charles F. Simmons
  • DIAGNOSTIC BIOMARKER TO PREDICT WOMEN AT RISK FOR PRETERM DELIVERY
    Publication number: 20140051598
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers including but not limited to cytokines, cytokine receptors, cytokine receptor antagonists, chemokines, chemokine receptors, and/or chemokine receptor antagonists found in women that are at risk for preterm delivery. The diagnostic methods may be performed on whole blood.
    Type: Application
    Filed: March 13, 2012
    Publication date: February 20, 2014
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem Equils, Charles F. Simmons
  • DIAGNOSTIC BIOMARKER TO IDENTIFY WOMEN AT RISK FOR PRETERM DELIVERY
    Publication number: 20120238469
    Abstract: The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.
    Type: Application
    Filed: December 7, 2010
    Publication date: September 20, 2012
    Applicant: Cedars-Sinai Medical Center
    Inventors: Ozlem Equils, Charles F. Simmons
  • CASPASE INHIBITORS IN THE TREATMENT OF INFECTION-ASSOCIATED PRETERM DELIVERY
    Publication number: 20100292174
    Abstract: Apoptotic processes induced by infection of, or injury to, fetal and placental tissues have been implicated in preterm delivery. Thus, modulation of apoptotis constitutes a strategy for improving pregnancy outcome in women with intrauterine infections. Caspase inhibitors, including the pancaspase inhibitor Z-VAD-FMK, can be used to prevent apoptosis and, thus, prevent preterm delivery. Accordingly, compositions and methods comprising caspase inhibitors for prevention of preterm delivery are provided.
    Type: Application
    Filed: May 1, 2008
    Publication date: November 18, 2010
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem Equils, Calvin Hobel, Charles F. Simmons
  • METHODS OF PRODUCING PREADIPOCYTES AND INCREASING THE PROLIFERATION OF ADULT ADIPOSE STEM/PROGENITOR CELLS
    Publication number: 20090317367
    Abstract: The present invention describes preadipocytes and methods of differentiating macrophages into preadipocytes by co-culturing adipocytes and resident adipose tissue macrophages. Also described are methods of increasing the proliferative rate of adipose adult stem/progenitor cells.
    Type: Application
    Filed: February 21, 2008
    Publication date: December 24, 2009
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Gregorio Chazenbalk, Cristina Bertolotto, Ricardo Azziz, Charles F. Simmons, Jr., Saleh Heneidi