Patents by Inventor CHARLES FERTE

CHARLES FERTE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiomics-based imaging tool to monitor tumor-lymphocyte infiltration and outcome in cancer patients treated by anti-PD-1/PD-L1
    Patent number: 12590949
    Abstract: The present invention proposes a radiomics-based biomarker for detecting the presence and the density of tumor infiltrating CD8 T-cells in a solid tumor without having to use any biopsy of said tumor. The invention also proposes to use this information to assess the immune phenotype of said solid tumor. In a particular embodiment, the invention proposes to prognose the survival and/or the treatment efficiency of cancer patients treated with immunotherapy such as anti-PD-1/PD-L1 monotherapy.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: March 31, 2026
    Assignees: Institut National de la Sante et de la Recherche Medicale, Universite Paris-Saclay
    Inventors: Charles Ferte, Elaine Johanna Limkin, Roger Sun, Eric Deutsch
  • Methods for determining treatment for cancer patients
    Patent number: 12224043
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Grant
    Filed: September 13, 2023
    Date of Patent: February 11, 2025
    Assignee: MEDIMMUNE, LLC
    Inventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20230420081
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: September 13, 2023
    Publication date: December 28, 2023
    Inventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
  • Methods for determining treatment for cancer patients
    Patent number: 11798653
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDIMMUNE, LLC
    Inventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
  • TREATMENT METHODS USING CTLA-4 AND PD-1 BISPECIFIC ANTIBODIES
    Publication number: 20230322928
    Abstract: The present disclosure provides methods of administering bispecific antibodies and antigen-binding fragments thereof that specifically bind to human Programmed cell-death-1 (PD-1) and Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) to a subject in need thereof, for example, a subject with cancer.
    Type: Application
    Filed: March 6, 2023
    Publication date: October 12, 2023
    Inventors: Daniel J. FREEMAN, Xuyang SONG, Shelby GAINER, Deepa SUBRAMANIAM, Ikbel ACHOUR, Charles FERTE
  • BISPECIFIC ANTIBODY TARGETING PD-1 AND TIM-3
    Publication number: 20220332818
    Abstract: The present disclosure provides methods of altering engagement between T-cell immunoglobulin and mucin domain containing protein-3 (TIM-3) and phosphatidylserine (PS) in a subject. Also provided are methods of treatment using TIM-3 binding protein wherein the TIM-3 binding domain specifically binds to the C?C? and DE loops of the immunoglobulin variable (IgV) domain of TIM-3.
    Type: Application
    Filed: April 12, 2022
    Publication date: October 20, 2022
    Inventors: Kristen POLLIZZI, Scott A. HAMMOND, Yariv MAZOR, Trinity PERRY, Stacy PRYTS, Ashvin R. JAISWAL, Vaheh OGANSEYAN, Chunning YANG, Raffael KUREK, Natalia CEAICOVSCAIA, Charles FERTE, Eleanor CLANCY-THOMPSON
  • A Radiomics-Based Imaging Tool to Monitor Tumor-Lymphocyte Infiltration and Outcome in Cancer Patients Treated by Anti-PD-1/PD-L1
    Publication number: 20210003555
    Abstract: The present invention proposes a radiomics-based biomarker for detecting the presence and the density of tumor infiltrating CD8 T-cells in a solid tumor without having to use any biopsy of said tumor. The invention also proposes to use this information to assess the immune phenotype of said solid tumor. In a particular embodiment, the invention proposes to prognose the survival and/or the treatment efficiency of cancer patients treated with immunotherapy such as anti-PD-1/PD-L1 monotherapy.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 7, 2021
    Applicant: INSTITUT GUSTAVE-ROUSSY
    Inventors: Charles FERTE, Elaine Johanna LIMKIN, Roger SUN, Eric DEUTSCH
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20200191792
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: October 18, 2019
    Publication date: June 18, 2020
    Inventors: LI YU, HARRY YANG, MOHAMMED DAR, LORIN ROSKOS, JEAN-CHARLES SORIA, CHARLES FERTE, WEI ZHAO, ALINE GENDRIN BROKMANN, JOLYON FARIA, PRALAY MUKHOPADHYAY
  • METHODS FOR DETERMINING TREATMENT FOR CANCER PATIENTS
    Publication number: 20200126636
    Abstract: Methods for determining treatments for cancer patients are disclosed.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 23, 2020
    Inventors: LI YU, HARRY YANG, MOHAMMED DAR, LORIN ROSKOS, JEAN-CHARLES SORIA, CHARLES FERTE, WEI ZHAO, ALINE GENDRIN BROKMANN, JOLYON FARIA, PRALAY MUKHOPADHYAY