Abstract: Disclosed is a T-fastener delivery device. The device includes a belt and a pusher rod. The belt includes a plurality of slots for holding a plurality of T-bars substantially parallel to one another in a side-by-side arrangement; and the belt is moveable such that the slots can be sequentially aligned with the pusher rod. Also disclosed are methods for creating a gastric pouch in the stomach of an obese patient and methods for reducing lower esophageal sphincter distraction with gastric filling in a subject. Suturing systems are also disclosed One suturing system includes a plurality of T-fasteners and a continuous suture connecting the plurality of T-fasteners. The T-fastener comprises a cylindrical bar having a filament loop attached thereto substantially at the cylindrical bar's axial midpoint, and the continuous suture slidably passes through the T-fasteners' filament loops. Another suturing system includes a plurality of T-fasteners; and a continuous suture connecting the plurality of T-fasteners.

Abstract: A surgical system for performing gastroplasty is disclosed. The system includes an elongated body adapted to be inserted into the esophagus with a proximal end extending from a body orifice. A working member includes a pair of elongated suction cavities that capture and excise portions of the anterior and posterior stomach walls and apply sutures to the captured tissue, which, when drawn tight, serve to create a modified lumen in the stomach.

Abstract: The present invention relates to a prosthetic anti-reflux valve for treating gastroesophageal reflux disease (GERD) and methods for its use. The preferred methods described provide for transoral insertion of a prosthetic anti-reflux valve and its fixation within the stomach interior. One advantage of such preferred embodiment of the present invention over prior devices is the elimination of the need for fixation of a prosthetic device within the esophagus, thus permitting a more natural and less obstructed, and even unobstructed, function of the esophagus.