Abstract: The present invention relates to a device for determining information relating to a suspected occluding structure. It is described to provide (210) a spectral resolving unit with at least one broadband radiation. The at least one broadband radiation comprises a first broadband radiation acquired from a region of interest within a vascular structure. An occluding structure is suspected to be located within the region of interest and wherein the first broadband radiation is associated with the suspected occluding structure. At least one spectrally resolved data set is determined (220) on the basis of the at least one broadband radiation, wherein the at least one spectrally resolved data set comprises a first spectrally resolved data set determined on the basis of the first broadband radiation. A processing unit is provided (230) with the at least one spectrally resolved data set on the basis of the at least one broadband radiation.

Abstract: The present invention relates to a device for determining information relating to a suspected occluding structure. It is described to provide (210) a spectral resolving unit with at least one broadband radiation. The at least one broadband radiation comprises a first broadband radiation acquired from a region of interest within a vascular structure. An occluding structure is suspected to be located within the region of interest and wherein the first broadband radiation is associated with the suspected occluding structure. At least one spectrally resolved data set is determined (220) on the basis of the at least one broadband radiation, wherein the at least one spectrally resolved data set comprises a first spectrally resolved data set determined on the basis of the first broadband radiation. A processing unit is provided (230) with the at least one spectrally resolved data set on the basis of the at least one broadband radiation.

Abstract: Presented is a system and method for assessing the functional ability of a person to perform a task. The system comprises: a task identification unit adapted to identify the task to be performed by the person; and a task complexity unit adapted to obtain a task-specific complexity signal representative of a required level of functional ability to perform the identified task. A functional ability unit is adapted to obtain a functional ability signal representative of a determined functional ability of the person. An assessment unit is adapted to determine an ability of the person to perform the identified task based on the task-specific complexity signal and the functional ability signal.

Abstract: There is provided a method of assessing the reliability of a measurement of blood pressure of a subject, the method in a control unit of an apparatus comprising obtaining a first measurement of at least one physiological characteristic of the subject that is indicative of the level of pain and/or stress of the subject, wherein the first measurement is made prior to a measurement of blood pressure being made; obtaining the measurement of blood pressure of the subject; obtaining a second measurement of the at least one physiological characteristic of the subject, wherein the second measurement is made after the measurement of blood pressure is made and prior to a subsequent measurement of blood pressure being made; and determining if the measurement of blood pressure is reliable based on the first measurement and the second measurement, wherein the measurement of blood pressure is determined to be reliable if the first measurement and the second measurement indicate a low level of pain and/or stress.

Abstract: The invention relates to determining a representation of cardiac output in a patient. Provided are a method and a system for monitoring a cardiac output using a single device inserted into a Central Venous Catheter (CVC) or Peripheral Inserted Central Catheters (PICC) line. In an embodiment, the device contains an elongated body that fits the lumen of a Central Venous Cava or Peripheral Inserted Central Catheters line and has an ultrasound transducer at the tip. By operating the device such that the velocity in both the Superior Vena Cava and Inferior Vena Cava can be sampled continuously the CO is monitored.

Abstract: There is provided a method of assessing the reliability of a measurement of blood pressure of a subject, the method in a control unit of an apparatus comprising obtaining a first measurement of at least one physiological characteristic of the subject that is indicative of the level of pain and/or stress of the subject, wherein the first measurement is made prior to a measurement of blood pressure being made; obtaining the measurement of blood pressure of the subject; obtaining a second measurement of the at least one physiological characteristic of the subject, wherein the second measurement is made after the measurement of blood pressure is made and prior to a subsequent measurement of blood pressure being made; and determining if the measurement of blood pressure is reliable based on the first measurement and the second measurement, wherein the measurement of blood pressure is determined to be reliable if the first measurement and the second measurement indicate a low level of pain and/or stress.

Abstract: Presented is a system and method for assessing the functional ability of a person to perform a task. The system comprises: a task identification unit adapted to identify the task to be performed by the person; and a task complexity unit adapted to obtain a task-specific complexity signal representative of a required level of functional ability to perform the identified task. A functional ability unit is adapted to obtain a functional ability signal representative of a determined functional ability of the person. An assessment unit is adapted to determine an ability of the person to perform the identified task based on the task-specific complexity signal and the functional ability signal.

Abstract: The present invention relates to a device for monitoring an eye of a subject, comprising: a transparent carrier for being in contact with the eye of the subject; and a photosensor facing the eye of the subject for receiving light reflected from the eye of the subject and for determining a light intensity of the received light, wherein the photosensor is arranged on the transparent carrier; and wherein the photosensor includes one of: a plurality of photodetectors arranged in the form of a two-dimensional array and spaced apart from one another for allowing incident light to pass between the photodetectors to enter the eye of the subject wherein the plurality of photodetectors is arranged in a plurality of rows of photodetectors or in a plurality of concentric circles substantially covering the iris and the pupil of the eye of the subject; and a single large area photodetector covering an iris and a pupil of the eye of the subject.

Abstract: The present invention relates to a method for determining a state of tissue sealing during a tissue sealing process. According to the disclosed method, an optical probe beam is used to irradiate a tissue region. A signal indicative of optical scattering in the tissue region is generated from a portion of the optical probe beam that has passed through or been returned by the tissue region. The onset of tissue sealing is indicated by the successive occurrence in time of a turning point and a point of inflection in the optical scattering signal. An energy-based tissue sealing or tissue-cutting device for use in accordance with the method is also disclosed.

Abstract: The present invention relates to a device for determining information relating to a suspected occluding structure. It is described to provide (210) a spectral resolving unit with at least one broadband radiation. The at least one broadband radiation comprises a first broadband radiation acquired from a region of interest within a vascular structure. An occluding structure is suspected to be located within the region of interest and wherein the first broadband radiation is associated with the suspected occluding structure. At least one spectrally resolved data set is determined (220) on the basis of the at least one broadband radiation, wherein the at least one spectrally resolved data set comprises a first spectrally resolved data set determined on the basis of the first broadband radiation. A processing unit is provided (230) with the at least one spectrally resolved data set on the basis of the at least one broadband radiation.

Abstract: Devices, systems and methods for pulse wave velocity determination in a renal artery are disclosed. An intravascular system may be included with two or more sensors disposed a certain distance apart on a flexible, elongate member. The sensors may be configured to receive pressure measurements associated with pulse waves moving through the renal artery, at different times. This difference in time and the distance between the 5 sensors may be used to calculate pulse wave velocity.

Abstract: Devices, systems, and methods for pulse wave velocity determination are disclosed. The apparatus includes an intravascular device that can be positioned within a vessel. The intravascular device includes a flexible elongate member having a proximal portion and a distal portion. A pressure sensor can be coupled to the distal portion of the flexible elongate member. The pressure sensor can monitor pressure within the vessel. At least one imaging element can be coupled to the distal portion of the flexible elongate member. The imaging element can monitor the wall thickness of the vessel. A processing system in communication with the intravascular device can control the monitoring of the pressure and the monitoring of the wall thickness of the vessel. The processing system can receive pressure data and wall thickness data and determine a pulse wave velocity of fluid within the vessel.

Abstract: Devices, systems and methods for pulse wave velocity determination in a renal artery are disclosed. An intravascular system may be included with two or more sensors disposed a certain distance apart on a flexible, elongate member. The sensors may be configured to measure changes in measurement value of the renal artery, such as the diameter of the renal artery and/or a distance between the sensors and the vessel walls, with pulse waves moving through the renal arter. The difference in the time at which the sensors measure these changes and the distance between the sensors may be used to calculate pulse wave velocity.

Abstract: Devices, systems, and methods for pulse wave velocity determination are disclosed. The apparatus includes an intravascular device that can be positioned within a renal artery. The intravascular device includes a flexible elongate member having a proximal portion and a distal portion. A pressure sensor can be coupled to the distal portion of the flexible elongate member. The pressure sensor can monitor a pressure within the renal artery. At least one imaging element can be coupled to the distal portion of the flexible elongate member. The imaging element can monitor a cross-sectional area of the renal artery. A processing system in communication with the intravascular device can control the monitoring of the pressure within the renal artery and the cross-sectional area of the renal artery. The processor can receive pressure data and cross-sectional area data and determine a pulse wave velocity of fluid within the renal artery.

Abstract: Devices, systems and methods for pulse wave velocity determination using intravascular pressure measurement and external ultrasound imaging are disclosed.

Abstract: Information regarding a patient's physiological signs is provided in real-time, in particular in conjunction with drug administration to the patient. A patient data input obtains patient data of a monitored patient. A drug identification input obtains drug administration data identifying a drug administered to the patient and the time of administration of the drug to the patient. A drug information input obtains drug information about the identified drug, including drug side effects and/or drug-drug interactions and/or drug-disease contraindications. A processing unit determines time-resolved monitoring information based on the obtained patient data, drug administration data and drug information. The monitoring information is dynamically adapted and one or more physiological signs of the patient that are most critical to monitor over time are indicated. An output interface outputs the monitoring information.

Abstract: The invention relates to a treatment apparatus for treating a gait irregularity of a person (1). The treatment apparatus (10) comprises a gait irregularity monitoring unit (11) for detecting a gait irregularity of the person, (a) cueing unit(s) (15, 16, 17), and a cueing control unit (14) for controlling the cueing unit(s) to provide, in response to the detection of the gait irregularity, a first cue set for treating the gait irregularity to the person. The gait irregularity monitoring unit monitors the effect of the providing of the first cue set to the person and determines whether the detected gait irregularity is being overcome. The cueing control unit controls the cueing unit(s) to provide a different second cue set to the person, if it has been determined that the detected gait irregularity has not been overcome. This improves the likelihood of being able to effectively treat the detected gait irregularity.

Abstract: A device for providing assistance to a person comprises a data input for obtaining person related data representing data obtained by monitoring the person, a data processing unit for processing the obtained person related data to determine the person's mental state and/or cognitive level from the obtained person related data, to detect if the person has limited or no ability to perform a desired task and to generate assistance data in case of detection that the person has limited or no ability to perform the desired task and/or if the person's current mental state and/or cognitive level is below a threshold or out of a distribution or value range required to perform the desired task, said assistance data representing data directed to supporting the person in performing the desired task by adapting the number of functions of an appliance accessible and controllable by the person according to the person's current mental state and/or cognitive level, and a data output for providing said assistance data for suppo

Abstract: The present invention relates to a device for monitoring an eye of a subject, comprising: a transparent carrier for being in contact with the eye of the subject; and a photosensor facing the eye of the subject for receiving light reflected from the eye of the subject and for determining a light intensity of the received light, wherein the photosensor is arranged on the transparent carrier; and wherein the photosensor includes one of: a plurality of photodetectors arranged in the form of a two-dimensional array and spaced apart from one another for allowing incident light to pass between the photodetectors to enter the eye of the subject wherein the plurality of photodetectors is arranged in a plurality of rows of photodetectors or in a plurality of concentric circles substantially covering the iris and the pupil of the eye of the subject; and a single large area photodetector covering an iris and a pupil of the eye of the subject.

Abstract: There is provided a contact lens for detecting changes in a property of ocular fluid. The contact lens comprises a lens part comprising an indicator material, wherein the volume of the indicator material is variable in dependence on a property of ocular fluid. The contact lens further comprises output means disposed on the lens part, wherein the output means is configured to provide an output which is variable in dependence on the volume of the indicator material.