Patents by Inventor Charles Frost
Charles Frost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200375968Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: ApplicationFiled: May 14, 2020Publication date: December 3, 2020Inventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Patent number: 10811716Abstract: An ion-conducting membrane includes: (i) a first ion-conducting layer including one or more first ion-conducting polymers; and (ii) a barrier layer including graphene-based platelets.Type: GrantFiled: July 10, 2013Date of Patent: October 20, 2020Assignee: Johnson Matthey Fuel Cells LimitedInventors: Jonathan Charles Frost, Jonathan David Brereton Sharman, Nadia Michele Permogorov
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Publication number: 20170202825Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: ApplicationFiled: March 30, 2017Publication date: July 20, 2017Inventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Publication number: 20170202824Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: ApplicationFiled: March 30, 2017Publication date: July 20, 2017Inventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Publication number: 20160243101Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: ApplicationFiled: March 31, 2016Publication date: August 25, 2016Inventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Patent number: 9326945Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: GrantFiled: February 24, 2011Date of Patent: May 3, 2016Assignees: Bristol-Myers Squibb Company, Pfizer Inc.Inventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Patent number: 9207192Abstract: An inspection system employs a cased pipeline structure, a pulse generator system, a data acquisition system, and a processing system. The cased pipeline structure comprises a casing pipe structure, a carrier pipe structure arranged within the casing pipe structure to define an annular space, and fill material arranged within the annular space. The pulse generator system is configured to apply an electromagnetic signal to the cased pipeline structure. The data acquisition system is configured to detect electromagnetic signals propagating along the cased pipeline structure. The processing system analyzes electromagnetic signals detected by the data acquisition system for signal characteristics indicative of an anomaly in the cased pipeline structure.Type: GrantFiled: May 29, 2013Date of Patent: December 8, 2015Assignee: WaveTrue, Inc.Inventors: Ronald J. Focia, Charles A. Frost
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Publication number: 20150180073Abstract: An ion-conducting membrane includes: (i) a first ion-conducting layer including one or more first ion-conducting polymers; and (ii) a barrier layer including graphene-based platelets.Type: ApplicationFiled: July 10, 2013Publication date: June 25, 2015Inventors: Jonathan Charles Frost, Jonathan David Brereton Sharman, Nadia Michele Permogorov
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Patent number: 8564303Abstract: An anomaly on an elongate conductive member is detected by causing a source electromagnetic wave to propagate in a first direction along the elongate conductive member such that the source electromagnetic wave passes through the at least one anomaly. The anomaly causes a reflected electromagnetic wave to propagate in a second direction along the elongate conductive member. The second direction is opposite the first direction. The electric field of the reflected electromagnetic wave is sensed. The magnetic field of the reflected electromagnetic wave is sensed. A direction of propagation of the reflected electromagnetic wave is determined based on the electric field of the reflected electromagnetic wave and the magnetic field of the reflected electromagnetic wave.Type: GrantFiled: January 6, 2010Date of Patent: October 22, 2013Assignee: WaveTrue, Inc.Inventors: Charles A. Frost, Ronald J Focia
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Publication number: 20130045245Abstract: Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 ?m, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.Type: ApplicationFiled: February 24, 2011Publication date: February 21, 2013Applicants: PFIZER, INC., BRISTOL-MYERS SQUIBB COMPANYInventors: Jatin Patel, Charles Frost, Jingpin Jia, Chandra Vemavarapu
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Publication number: 20110298477Abstract: Systems and methods for detecting an anomaly on an internal surface of a hollow, elongate, metallic pipe structure. An anomaly detection system employs an access port, an antenna, a signal source, and a signal analyzer. The access port allows physical access to an interior of the pipe structure. The antenna extends into the interior of the pipe structure through the access port. The signal source is operatively connected to the antenna and is capable of causing the antenna to cause a test signal to be conducted along the pipe structure such that the anomaly reflects at least a portion of the test signal back towards the antenna as a reflected signal. The signal analyzer is operatively connected to the antenna to analyze, in a frequency domain, the reflected signal.Type: ApplicationFiled: May 10, 2011Publication date: December 8, 2011Applicant: PROFILE TECHNOLOGIES, INC.Inventors: Ronald J. Focia, Charles A. Frost
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Patent number: 7940061Abstract: Systems and methods for detecting anomalies, such as corrosion, on internal surfaces of hollow elongate bodies, such as pipelines. The pipeline is treated as a circular waveguide, and a fast rise time pulse or a spectrum of electromagnetic waves is launched down the waveguide to perform time domain, or equivalent of time domain (e.g., frequency domain), reflectometry. Anomalies in the internal structure of the pipeline cause reflections which can be measured and related to the physical parameters of the pipeline structure and identified to a particular location.Type: GrantFiled: November 30, 2007Date of Patent: May 10, 2011Assignee: Profile Technologies, Inc.Inventors: Ronald J. Focia, Charles A. Frost
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Patent number: 7867299Abstract: Methods and apparatus for producing hydrogen with reforming catalysts. The reforming catalysts may be platinum group metals on a support material, and they may be located in a reforming reaction zone of a primary reactor. The support material may be an oxidic support having a ceria and zirconia promoter, or may include a neodymium stabilizer. The support material may also include at least one Group IA, Group IIA, manganese, or iron metal promoter. The primary reactor may have a first and second reforming reaction zones, where upstream catalysts located in the first reforming reaction zone and downstream catalysts located in the second reforming reaction zone may be selected to perform optimally under the conditions in their respective reforming reaction zone.Type: GrantFiled: March 3, 2005Date of Patent: January 11, 2011Assignee: GM Global Technology Operations LLCInventors: Michael Ian Petch, Jonathan Charles Frost, Suzanne Rose Ellis, Jessica Grace Reinkingh, Mark Robert Feaviour, Jillian Elaine Bailie, David Wails, Paul James Millington
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Publication number: 20100322711Abstract: A synthetic resin article is provided for use in a fluid diversion system with one or more distribution lines. The article's frame has a top, at least one side, a bottom and an interior. At least one aperture is formed at the top. An intake port is disposed on at least one side of the frame, for engagement with the system distribution line. A drainage structure is disposed on the bottom of the frame for downward drainage of standing water into the surrounding soil or other environment. When the system delivers fluid through the distribution line, it is received in the interior of the frame and drains slowly out through the drainage structure but normally when the system delivers fluid to the interior at a sufficient rate, the fluid rises to the top of the frame and percolates out of the outlet aperture. In preferred embodiments, the top includes a plurality of small outlet gratings for additional percolation.Type: ApplicationFiled: May 3, 2010Publication date: December 23, 2010Inventor: Gregory Charles Frost
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Publication number: 20100171483Abstract: An anomaly on an elongate conductive member is detected by causing a source electromagnetic wave to propagate in a first direction along the elongate conductive member such that the source electromagnetic wave passes through the at least one anomaly. The anomaly causes a reflected electromagnetic wave to propagate in a second direction along the elongate conductive member. The second direction is opposite the first direction. The electric field of the reflected electromagnetic wave is sensed. The magnetic field of the reflected electromagnetic wave is sensed. A direction of propagation of the reflected electromagnetic wave is determined based on the electric field of the reflected electromagnetic wave and the magnetic field of the reflected electromagnetic wave.Type: ApplicationFiled: January 6, 2010Publication date: July 8, 2010Applicant: PROFILE TECHNOLOGIES, INC.Inventors: Charles A. Frost, Ronald J. Focia
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Patent number: 7642790Abstract: A system or method of analyzing a conductive member for the presence an anomaly. A conductive pipe member is analyzed for the presence an anomaly the electromagnetic properties of which are non-linear. The electromagnetic properties of the pipe member at the anomaly are altered by applying a direct current perturbation signal to the pipe member. At least one test source signal is applied to a first test location on the pipe member remote from the anomaly to cause the at least one test source signal to travel along the pipe through the anomaly. At least one test return signal associated with the at least one test source signal traveling through the anomaly is detected. The at least one test return signal is analyzed for characteristics associated with the anomaly.Type: GrantFiled: March 27, 2007Date of Patent: January 5, 2010Assignee: Profile Technologies, Inc.Inventors: Gale D. Burnett, Charles A. Frost
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Publication number: 20080191706Abstract: A system or method of analyzing a conductive member for the presence an anomaly. A conductive pipe member is analyzed for the presence an anomaly the electromagnetic properties of which are non-linear. The electromagnetic properties of the pipe member at the anomaly are altered by applying a direct current perturbation signal to the pipe member. At least one test source signal is applied to a first test location on the pipe member remote from the anomaly to cause the at least one test source signal to travel along the pipe through the anomaly. At least one test return signal associated with the at least one test source signal traveling through the anomaly is detected. The at least one test return signal is analyzed for characteristics associated with the anomaly.Type: ApplicationFiled: March 27, 2007Publication date: August 14, 2008Inventors: Gale D. Burnett, Charles A. Frost
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Publication number: 20080143344Abstract: Systems and methods for detecting anomalies, such as corrosion, on internal surfaces of hollow elongate bodies, such as pipelines. The pipeline is treated as a circular waveguide, and a fast rise time pulse or a spectrum of electromagnetic waves is launched down the waveguide to perform time domain, or equivalent of time domain (e.g., frequency domain), reflectometry. Anomalies in the internal structure of the pipeline cause reflections which can be measured and related to the physical parameters of the pipeline structure and identified to a particular location.Type: ApplicationFiled: November 30, 2007Publication date: June 19, 2008Inventors: Ronald J. Focia, Charles A. Frost
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Publication number: 20080011588Abstract: A section of chain for conveying product along a material handling system includes a pin connecting a center link between two side links. The pin may be dialable or selectably positioned at the side links to control and adjust the wear surface of the pin relative to the chain links. The pin may have a rotationally non-symmetrical shaft portion to provide different wear surfaces that engage a center link of the section of chain. The different wear surfaces may be sized and shaped to accommodate wear at the wear surface of the center link. The shaft portion may include a rotationally non-symmetrical ball member or portion on the shaft portion to enhance flexibility of the section of chain. The pin may be dialed to the next position or wear surface in response to an output of a wear measurement device or system.Type: ApplicationFiled: July 23, 2007Publication date: January 17, 2008Applicant: FROST LINKS, INC.Inventors: Charles Frost, Jonathan Rathbun, Ryan Kastamo
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Publication number: 20070193860Abstract: A chain pin or pin element for connecting chain links together to form a section of a chain for conveying products along a conveyor line or path of a material handling system includes a shaft portion and a head portion at at least one end of the shaft portion. The shaft portion is received through respective chain links to define a joint of the section of chain, while the head portion or head portions retain the pin at the links. At least one head portion of at least some of the pins includes a reservoir and a channel formed therein. The reservoir is configured to receive a lubricating fluid, such as from a lubricating device of the material handling system, while the channel functions to distribute the lubricant from the reservoir and toward and onto the shaft portion of the pin to lubricate the joint of the chain.Type: ApplicationFiled: February 16, 2007Publication date: August 23, 2007Applicant: Frost Links, Inc.Inventors: Charles Frost, Jonathan Rathbun