Patents by Inventor Charles G. Todderud

Charles G. Todderud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification and cloning of a novel human gene, RET16, involved in the intracellular signaling cascade
    Patent number: 7678887
    Abstract: The present invention describes a newly discovered polynucleotide encoding a protein involved in the cell signaling cascade, called RET16, cloned, isolated and identified from TNF-alpha stimulated human microvascular endothelial cells, as well as mouse and rat RET16 orthologs thereof. Also described are the RET16 polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Methods for screening for modulators, particularly inhibitors, of the human RET16 protein, and use of the RET16 polynucleotide and polypeptide for therapeutics and diagnostics are described.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: March 16, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Charles G. Todderud, Joshua N. Finger, Jill Rillema