Abstract: Systems and methods are disclosed for processing medical images. One method includes: receiving a patient-specific vessel model of one or more vessels of a patient and a patient-specific tissue model of a tissue supplied by the one or more vessels, wherein the patient-specific vessel model and the patient-specific tissue model are derived from the medical images of the patient; determining one or more patient-specific values of one or more anatomical or physiological parameters based on the patient-specific vessel model or the patient-specific tissue model; determining an estimated supplied blood to the tissue; computing an estimate of a perfusion of blood in the tissue based on the determined patient-specific values of the one or more anatomical or physiological parameters and the determined estimated supplied blood to the tissue; generating a visualization of the computed estimate of the perfusion of blood; and displaying the estimate of the perfusion on an electronic display.

Abstract: The present disclosure provides for a flow therapy apparatus that can implement one or more closed loop control systems to control the flow of gases of a flow therapy apparatus. The flow therapy apparatus can monitor blood oxygen saturation (SpO2) of a patient and control the fraction of oxygen delivered to the patient (FdO2). The flow therapy apparatus can automatically adjust the FdO2 in order to achieve a targeted SpO2 value for the patient.

Abstract: The present disclosure provides for a flow therapy apparatus that can implement one or more closed loop control systems to control the flow of gases of a flow therapy apparatus. The flow therapy apparatus can monitor blood oxygen saturation (SpO2) of a patient and control the fraction of oxygen delivered to the patient (FdO2). The flow therapy apparatus can automatically adjust the FdO2 in order to achieve a targeted SpO2 value for the patient.

Abstract: Systems and methods can determine respiratory rates of a patient using a respiratory device by performing one or more frequency analyses of a signal from the gases flow. The signal from the gases flow can be one that varies with the patient's breathing. The system can include a non-sealed patient interface, such as a nasal cannula in a nasal high flow therapy, or any other patient interfaces. The respiratory system can also detect whether the patient has taken off the patient interface and/or whether the patient connected to the patient interface is talking or eating. Data of the patient's use of the respiratory system and the patient's respiratory rates can provide therapy compliance and long-term trend of use information and/or progress in the patient's respiratory functions and/or other physiological functions.

Abstract: Systems and methods can determine respiratory rates of a patient using a respiratory device by performing one or more frequency analyses of a signal from the gases flow. The signal from the gases flow can be one that varies with the patients breathing. The system can include a non-sealed patient interface, such as a nasal cannula in a nasal high flow therapy, or any other patient interfaces. The respiratory system can also detect whether the patient has taken off the patient interface and/or whether the patient connected to the patient interface is talking or eating. Data of the patients use of the respiratory system and the patients respiratory rates can provide therapy compliance and long-term trend of use information and/or progress in the patients respiratory functions and/or other physiological functions.

Abstract: This disclosure enables displaying of an intuitive and engaging enquiry on a touchscreen of a medical device (e.g., breathing apparatus, breathing assistance apparatus) that a patient is already using (e.g., in-home medical device). Since the patient is already accustomed to using the medical device for medical treatment control, the patient, who may be unwell, is more likely to access the enquiry and complete the enquiry. Further, making the enquiry intuitive and engaging encourages the patient to regularly interact with the enquiry, while ensuring that the enquiry is not overly tedious to complete. Responding to the enquiry can be made mandatory by refraining from activating or preventing activation of a component of the apparatus until a predetermined set of responses has been received.

Abstract: The present disclosure provides for a flow therapy apparatus that can implement one or more closed loop control systems to control the flow of gases of a flow therapy apparatus. The flow therapy apparatus can monitor blood oxygen saturation (SpO2) of a patient and control the fraction of oxygen delivered to the patient (FdO2). The flow therapy apparatus can automatically adjust the FdO2 in order to achieve a targeted SpO2 value for the patient.

Abstract: A computer-implemented method for selecting participants from an applicant pool to participate in a program to exit poverty is described. The method implemented using a computing device in communication with a memory. The method includes storing a plurality of questions to ask each applicant from a pool of applicants, storing a plurality of ratings based on historical data wherein each rating is associated with each of one or more potential answers for each question of the plurality of questions, compiling by the computing device one or more scores for the applicant based on the applicant's answers to the plurality of questions and the plurality of ratings, calculating by the computing device the applicant's overall score based on the one or more scores, determining the applicant's ranking in comparison to the pool of applicants, and outputting the rankings of the applicants.

Abstract: Systems and methods can determine respiratory rates of a patient using a respiratory device by performing one or more frequency analyses of a signal from the gases flow. The signal from the gases flow can be one that varies with the patients breathing. The system can include a non-sealed patient interface, such as a nasal cannula in a nasal high flow therapy, or any other patient interfaces. The respiratory system can also detect whether the patient has taken off the patient interface and/or whether the patient connected to the patient interface is talking or eating. Data of the patients use of the respiratory system and the patients respiratory rates can provide therapy compliance and long-term trend of use information and/or progress in the patients respiratory functions and/or other physiological functions.

Abstract: The present invention relates to the fermentative production of alcohols including ethanol and butanol, and processes for improving alcohol fermentation employing in situ product removal methods.

Abstract: The present invention relates to the fermentative production of alcohols including ethanol and butanol, and processes for improving alcohol fermentation employing in situ product removal methods.

Abstract: In an alcohol fermentation process, oil derived from biomass is hydrolyzed into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be catalytically (e.g., enzymatically) hydrolyzed into free fatty acids, which form a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be hydrolyzed by contacting the feedstock including the oil with one or more enzymes whereby at least a portion of the oil is hydrolyzed into free fatty acids forming a fermentation product extractant, or the oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be contacted with the enzymes to form the fermentation product extractant.

Abstract: Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway.

Abstract: In an alcohol fermentation process, oil derived from biomass is chemically converted into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be chemically converted into a reaction product, such as fatty acids, fatty alcohols, fatty amides, fatty acid methyl esters, fatty acid glycol esters, and hydroxylated triglycerides, and mixtures thereof, which forms a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be chemically converting into the fermentation product extractant.

Abstract: An alcohol fermentation process and composition that includes production of alcohol esters by esterification of product alcohol in a fermentation medium with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product alcohol, such as butanol, with the carboxylic acid to form the alcohol esters. The alcohol esters can be extracted from the fermentation medium, and the product alcohol recovered from the alcohol esters. The carboxylic acid can also serve as an extractant for removal of the alcohol esters from the fermentation medium.

Abstract: The present invention relates to the production of fermentation products such as alcohols including ethanol and butanol, and processes employing in situ product removal methods.

Abstract: A computer-implemented method for selecting participants from an applicant pool to participate in a program to exit poverty is described. The method implemented using a computing device in communication with a memory. The method includes storing a plurality of questions to ask each applicant from a pool of applicants, storing a plurality of ratings based on historical data wherein each rating is associated with each of one or more potential answers for each question of the plurality of questions, compiling by the computing device one or more scores for the applicant based on the applicant's answers to the plurality of questions and the plurality of ratings, calculating by the computing device the applicant's overall score based on the one or more scores, determining the applicant's ranking in comparison to the pool of applicants, and outputting the rankings of the applicants.

Abstract: An alcohol fermentation process and composition that includes production of alcohol esters by esterification of product alcohol in a fermentation medium with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product alcohol, such as butanol, with the carboxylic acid to form the alcohol esters. The alcohol esters can be extracted from the fermentation medium, and the product alcohol recovered from the alcohol esters. The carboxylic acid can also serve as an extractant for removal of the alcohol esters from the fermentation medium.

Abstract: A process for recovering alcohol from a fatty acid and/or diacid alcohol ester using water in an equal or lesser amount than oil on a mass basis. The process uses multiple reactors with separation of the alcohol product of hydrolysis between successive reactors. The use of low amounts of water allows recovery of the alcohol with a lower evaporation requirement, thus making a more energy efficient process.

Abstract: A method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible organic extractant in the presence of at least one electrolyte at a concentration at least sufficient to increase the butanol partition coefficient relative to that in the presence of the salt concentration of the basal fermentation medium, is provided. The electrolyte may comprise a salt which dissociates in the fermentation medium, or in the aqueous phase of a biphasic fermentation medium, to form free ions. Also provided is a method and composition for recovering butanol from a fermentation medium.