Abstract: An air cleaner box for a computer or other electronic equipment is disclosed in which the computer or other electronic equipment is inserted into an enclosure which is sealed from the outside environment in such a manner that all of the air entering the enclosure must do so through an electronic or other type of air cleaner which serves to remove the dirt, dust, smoke and other air borne contaminants from the environment before they reach the electronic equipment contained in the enclosure. The enclosure contains within it all of the equipment for operating the air cleaner filter as well as a cable access box which allows computer cables to be routed from the outside environment into the contaminant-free enclosure while providing a tight seal against air infiltration from the outside environment.