Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: An integrated, single collar measurement while-while-drilling tool is presented that comprises formation sensors, directional sensors, pressure sensors, a mud pulse telemetry device, and a turbine-generator power device configured in a single collar housing that is no longer than a standard drill collar. No electrical connections are made across drill collar tool joints. The tool provides high reliability and ease of transportation.

Abstract: An integrated, single collar measurement while-while-drilling tool is presented that comprises formation sensors, directional sensors, pressure sensors, a mud pulse telemetry device, and a turbine-generator power device configured in a single collar housing that is no longer than a standard drill collar. No electrical connections are made across drill collar tool joints. The tool provides high reliability and ease of transportation.

Abstract: A compound having a polysaccharide binding domain such as contained by a cellulose and essentially lacking in polysaccharidase activity is purified from other ingredients in a mixture using an affinity partition system. A mixture containing the compound is contacted with a system containing as a first phase an aqueous solution of oligosaccharide polymer such as cellulose and as a second phase a solution of a polymer such as a poly(ethylene glycol)-poly(propylene glycol) copolymer. The compound petitions into the first phase and binds to the oligosaccharide polymer, preferably with a Ka of 103 to 107, to form a complex. The complex is collected, and the compound is dissociated from the oligosaccharide polymer. The compound may be formed of a non-peptide chemical moiety or a peptide moiety linked to a polypeptide having the polysaccharide binding domain.

Abstract: In a two-stage, electrostatic precipitator for extracting airborne particles, charged plates are electrically connected to each other and physically separated from each other by ferrite spacers so that an impedance of the spacers limits an amount of arc discharge current that will flow when an arc discharge occurs from one of the charged plates. Ferrite spacers can also be provided to electrically connect and physically separate grounded plates in the precipitator. In addition, aluminum spacers can be provided to adjust the impedance of the series of spacers through which an arc discharge current flows, so that the current is a minimum necessary amount for an arc detection circuit to detect.

Abstract: A two-phase partition system is provided for affinity separation of a composition containing a polysaccharide binding peptide from a mixture such as a fermentation broth. The peptide may be from an enzyme and lacking in polysaccharidase activity such as the binding domain of cellulase that binds to cellulose. The system contains a phase-forming oligosaccharide polymer such as a cellulose derivative to which the peptide binds with a Ka of 10.sup.3 M to 10.sup.7 M, and a phase inducing agent such as a polyethylene glycol polymer, or a salt present at sufficiently high concentration to induce phase separation. If the oligosaccharide polymer is thermoseparating, phase separation can be induced by heating. Using the system involves contacting a composition containing the peptide such as a fusion protein with the system, partitioning the composition into a phase containing the oligosaccharide polymer by binding to the polymer and recovering the polymer containing the bound composition.

Abstract: This invention pertains to a novel process for directly producing N-acetyl-D-glucosamine from chitin. More particularly, this invention pertains to a novel process for producing N-acetyl-D-glucosamine utilizing an ensemble of the chitinase family of enzymes to hydrolyze chitin of crustacea shells. The invention includes a process for producing N-acetyl-D-glucosamine by enzymatically hydrolyzing chitin with an ensemble of chitinolytic enzymes, including chitinase and chitobiase. In particular, using a two-stage chitin-hydrolysis reactor.

Abstract: An electrostatic air cleaner collector and/or ionizer section has their oppositely charged elements being formed of single, continuous, electrically conductive elements, spirally wound around insulator rods to jointly define a spiral passage through which air is caused to flow. The collector and ionizer may be assembled separately by such a winding process, or they may contain common insulator rods around which the conductive element of both sections may be simultaneously wound. A conductive rod may be inserted to electrically interconnect the high voltage elements of the respective ionizer and collector sections.

Abstract: An electrical resistance heating assembly having specially designed electrical insulators is disclosed. The electrical insulators have arms shaped to retain an electrical resistance heating coil which can be quickly, easily, and reliably mounted on the arms of the insulator. Top parts of the arms are generally rectangular or triangular in cross section and the arms are spaced and configured relative to each other to form a generally T-shaped opening between the arms, with the ends of the cross bar of the T-shaped opening forming electrically resistance heating coil retention surfaces. Also, cuts in side surfaces of the insulators may provide additional coil retention surfaces.

Abstract: A solar heating system adapted to provide heated air and water to a building structure with simple yet efficient components. The solar heating system comprises an air heating chamber which is exposed directly or indirectly to radiant solar energy, and air heated therein is directed to a heat exchange tank. The heated air from the air heating chamber is directed through bubble producing means, the bubbles rising through water contained in the heat exchange tank. Upon escaping from the heat exchange tank, the air may be directed to any one of three locations; firstly, the air may be directed back through the bubble producing means and into the water in the heat exchange tank, secondly, it may be directed to a building structure to provide heated, humidified air, and thirdly the escaping air may be directed to ambient atmosphere.

Abstract: A combination structure adapted for use in a catalytic process for stimulating the recovery of hydrocarbons from porous and permeable hydrocarbon bearing strata in earth formations utilizing at least one injection well and at least one production well both completed in said hydrocarbon bearing strata and a finely divided hydrocarbon cracking catalyst which is delivered by and through said structural combination of parts and elements to said strata by injection gas controlled at suitable pressure, temperature and O.sub.2 content to promote and advance in place catalytic cracking of hydrocarbons and catalyst regeneration within said strata to be produced by utilizing said combination structure or its equivalent.

Abstract: A catalytic process for stimulating the recovery of hydrocarbons from porous and permeable hydrocarbon bearing strata in earth formations utlizing at least one injection well and at least one production well both completed in said hydrocarbon bearing strata and a finely divided hydrocarbon cracking catalyst delivered to said strata by an injection gas controlled at suitable pressure, temperature and O.sub.2 content to promote and advance in place catalytic cracking of hydrocarbons and catalyst regeneration within said strata to be produced.