Patents by Inventor Charles J. Cox
Charles J. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11213660Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: GrantFiled: February 12, 2019Date of Patent: January 4, 2022Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Patent number: 11191932Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer run substantially parallel to one another and substantially parallel to the longitudinal axis. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length.Type: GrantFiled: March 24, 2020Date of Patent: December 7, 2021Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Publication number: 20200222673Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone wails and neck walls. The fibers of the first fiber layer run substantially parallel to one another and substantially parallel to the longitudinal axis. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length.Type: ApplicationFiled: March 24, 2020Publication date: July 16, 2020Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, JR.
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Patent number: 10646699Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer run substantially parallel to one another and substantially parallel to the longitudinal axis. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length.Type: GrantFiled: May 5, 2014Date of Patent: May 12, 2020Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Patent number: 10376679Abstract: A medical balloon comprises a first end, a second end spaced apart from the first, and a generally cylindrical balloon wall extending therebetween to define an inflation chamber. The balloon wall is adapted for inflation from a first folded configuration having a first plurality of pleats to an expanded, unpleated configuration, and deflation therefrom to a second folded configuration having a second plurality of pleats. The balloon wall includes a first layer formed of a polymer and having a substantially constant radial thickness. A second layer is firmly attached to the first layer and has a plurality of first regions of greater radial thickness interleaved with a plurality of second regions of reduced radial thickness. During deflation from the expanded, unpleated configuration to the second folded configuration, the balloon wall folds along the regions of reduced radial thickness of the second layer to form the second plurality of pleats.Type: GrantFiled: March 6, 2013Date of Patent: August 13, 2019Assignee: Biomerics FMI, LLCInventors: Charles J. Cox, William F. Davies, Jr., Lanny Pepper
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Publication number: 20190167956Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: ApplicationFiled: February 12, 2019Publication date: June 6, 2019Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, Jr.
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Patent number: 10226601Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: GrantFiled: May 16, 2016Date of Patent: March 12, 2019Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Patent number: 10099042Abstract: A catheter includes a balloon and a shaft having a coaxial portion including an outer tubular member having a bore, a transition neck, an access fitting adjacent the proximate end of the catheter shaft for directing a guidewire into the catheter shaft, an inflation port, a guidewire tubular member disposed coaxially in the outer tubular member, the outer tubular member and guidewire tubular member defining a first, annular inflation/deflation lumen fluid communication with the inflation port, at least one second inflation/deflation lumen separate from and non-coaxial with the guidewire tubular member and having a cross-sectional area less than the cross-sectional area of the first inflation/deflation lumen and opening at a proximate end into the first inflation/deflation lumen and at the distal end of the transition neck.Type: GrantFiled: September 19, 2016Date of Patent: October 16, 2018Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Patent number: 10004742Abstract: Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein said patient does not have one or more allelic polymorphisms selected from the group of: HLA-DQA1*0201, HLA-DQB1*0202, and HLA-DRB1*0701. Patients may also be free of genotypes in TNXB; rs12153855 and/or rs17207923.Type: GrantFiled: November 21, 2016Date of Patent: June 26, 2018Assignee: Novartis AGInventors: Nan Bing, Linda Perry Briley, Laura R. Parham, Charles J. Cox, Colin F. Spraggs
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Publication number: 20170065590Abstract: Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein said patient does not have one or more allelic polymorphisms selected from the group of: HLA-DQA1*0201, HLA-DQB1*0202, and HLA-DRB1*0701. Patients may also be free of genotypes in TNXB; rs12153855 and/or rs17207923.Type: ApplicationFiled: November 21, 2016Publication date: March 9, 2017Inventors: Nan Bing, Linda Perry Briley, Laura R. Parham, Charles J. Cox, Colin F. Spraggs
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Patent number: 9539257Abstract: Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein said patient does not have one or more allelic polymorphisms selected from the group of: HLA-DQA1*0201, HLA-DQB1*0202, and HLADRB1*0701. Patients may also be free of genotypes in TNXB; rs12153855 and/or rs17207923.Type: GrantFiled: February 27, 2015Date of Patent: January 10, 2017Assignee: Novartis AGInventors: Nan Bing, Linda Perry Briley, Laura R. Budde, Charles J. Cox, Colin F. Spraggs
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Publication number: 20170000987Abstract: A catheter includes a balloon and a shaft having a coaxial portion including an outer tubular member having a bore, a transition neck, an access fitting adjacent the proximate end of the catheter shaft for directing a guidewire into the catheter shaft, an inflation port, a guidewire tubular member disposed coaxially in the outer tubular member, the outer tubular member and guidewire tubular member defining a first, annular inflation/deflation lumen fluid communication with the inflation port, at least one second inflation/deflation lumen separate from and non-coaxial with the guidewire tubular member and having a cross-sectional area less than the cross-sectional area of the first inflation/deflation lumen and opening at a proximate end into the first inflation/deflation lumen and at the distal end of the transition neck.Type: ApplicationFiled: September 19, 2016Publication date: January 5, 2017Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, JR.
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Patent number: 9446223Abstract: A catheter includes a balloon and a shaft having a coaxial portion including an outer tubular member having a bore, a transition neck, an access fitting adjacent the proximate end of the catheter shaft for directing a guidewire into the catheter shaft, an inflation port, a guidewire tubular member disposed coaxially in the outer tubular member, the outer tubular member and guidewire tubular member defining a first, annular inflation/deflation lumen fluid communication with the inflation port, at least one second inflation/deflation lumen separate from and non-coaxial with the guidewire tubular member and having a cross-sectional area less than the cross-sectional area of the first inflation/deflation lumen and opening at a proximate end into the first inflation/deflation lumen and at the distal end of the transition neck.Type: GrantFiled: July 11, 2013Date of Patent: September 20, 2016Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Publication number: 20160256669Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: ApplicationFiled: May 16, 2016Publication date: September 8, 2016Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, JR.
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Patent number: 9339635Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: GrantFiled: February 24, 2014Date of Patent: May 17, 2016Assignee: BARD PERIPHERAL VASCULAR, INC.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.
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Publication number: 20150231137Abstract: Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein said patient does not have one or more allelic polymorphisms selected from the group of: HLA-DQA1*0201, HLA-DQB1*0202, and HLADRB1*0701. Patients may also be free of genotypes in TNXB; rs12153855 and/or rs17207923.Type: ApplicationFiled: February 27, 2015Publication date: August 20, 2015Inventors: Nan BING, Linda Perry Briley, Laura R. Budde, Charles J. Cox, Colin F. Spraggs
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Publication number: 20150012032Abstract: A medical balloon comprises a first end, a second end spaced apart from the first, and a generally cylindrical balloon wall extending therebetween to define an inflation chamber. The balloon wall is adapted for inflation from a first folded configuration having a first plurality of pleats to an expanded, unpleated configuration, and deflation therefrom to a second folded configuration having a second plurality of pleats. The balloon wall includes a first layer formed of a polymer and having a substantially constant radial thickness. A second layer is firmly attached to the first layer and has a plurality of first regions of greater radial thickness interleaved with a plurality of second regions of reduced radial thickness. During deflation from the expanded, unpleated configuration to the second folded configuration, the balloon wall folds along the regions of reduced radial thickness of the second layer to form the second plurality of pleats.Type: ApplicationFiled: March 6, 2013Publication date: January 8, 2015Inventors: Charles J. Cox, William F. Davies, JR., Lanny Pepper
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Publication number: 20140243874Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer run substantially parallel to one another and substantially parallel to the longitudinal axis. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length.Type: ApplicationFiled: May 5, 2014Publication date: August 28, 2014Applicant: BARD PERIPHERAL VASCULAR, INC.Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, JR.
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Publication number: 20140166193Abstract: A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.Type: ApplicationFiled: February 24, 2014Publication date: June 19, 2014Applicant: BARD PERIPHERAL VASCULAR, INC.Inventors: LANNY R. PEPPER, CHARLES J. COX, WILLIAM F. DAVIES, JR.
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Patent number: 8728110Abstract: A balloon dilation catheter includes a dilation balloon and a shaft having a coaxial portion including an outer tubular member having a bore, a proximate end and a distal end and a transition neck formed at the distal end of the coaxial portion, the transition neck having a proximate end at the distal end of the outer tubular member and a distal end, an access fitting adjacent the proximate end of the catheter shaft for directing a guidewire into the catheter shaft, an inflation port for directing an incompressible inflation medium into the catheter shaft, a guidewire tubular member disposed coaxially in the outer tubular member and extending continuously through the outer tubular member to the distal end of the outer tubular member and through the transition neck, the outer tubular member and guidewire tubular member defining a first, annular inflation/deflation lumen therebetween in fluid communication with the inflation port, at least one second inflation/deflation lumen formed through the transition neck,Type: GrantFiled: January 16, 2009Date of Patent: May 20, 2014Assignee: Bard Peripheral Vascular, Inc.Inventors: Lanny R. Pepper, Charles J. Cox, William F. Davies, Jr.